Rutgers Scarlet Knights vs Purdue Boilermakers Prediction, 10/25/2025 College Football Picks, Best Bets & Odds
Game: Rutgers Scarlet Knights vs Purdue Boilermakers
Date: Saturday, October 25, 2025
Location: Ross-Ade Stadium in West Lafayette, IN
TV: BTN
Odds/Point Spread: Boilermakers (+2.5)
Total/Over-Under: 59
The Rutgers Scarlet Knights (3-4) are hitting the road to Ross-Ade Stadium on Saturday, October 25, 2025 where they will try to beat the Purdue Boilermakers (2-5). Rutgers opens this game as 2.5-point favorites. The total is 59.
The Rutgers Scarlet Knights step onto the field holding a record of 3-4 for this season. In their last matchup, the Scarlet Knights faced the Oregon Ducks and took a loss by a score of 56-10. On the day, they had 69 plays for 202 yards. The Rutgers Scarlet Knights ran the ball 42 times and recorded 123 yards, which earned them an average of 2.9 yds per carry. Against the run, the Scarlet Knights gave up 415 yds on 37 tries, which is an average of 11.2 yds per rush surrendered. Rutgers gave up 18 pass completions on 24 attempts for a total of 335 yds, and a completion percentage of 75.0%.

The Scarlet Knights have earned 2,865 yards in total for the season. When it comes to scoring, Rutgers has amassed 13 passing touchdowns and 13 rushing touchdowns. They have surrendered the football 6 times. Rutgers has accounted for 174 1st downs, and they have been hurt by 31 penalties for 241 yards. As a unit they average 133.1 yards on the ground which has them sitting 95th in college football. When it comes to scoring points, the Rutgers Scarlet Knights are averaging 32.0 points per outing.
The Scarlet Knights rank 119th in D-1 when it comes to their opponents scoring, allowing 31.6 points per game. They are giving up an average of 6.0 yards per rush and 176.1 rushing yards per game this year. During the season, they have conceded 1,233 yards via the running game in 7 games. Concerning yards via the pass, the Scarlet Knights have allowed 1,829 yards which ranks them 123rd in the nation. They are allowing 261.3 yards per outing through the air in addition to giving up a completion percentage of 67.4%. During the season, they have yielded 437.4 yards/game which has them ranked 123rd in the nation. They have allowed 12 touchdowns by air as well as 16 touchdowns via the ground game.
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The Boilermakers come into this matchup with a record of 2-5 this year. The last time they took the field, the Boilermakers took a defeat with a final score of 19-0 when they played the Northwestern Wildcats. The Boilermakers finished the game with a total of 305 yds and they ran 56 plays (5.4 yards per play). Purdue rushed the football for 3.3 yds per carry, totaling 87 yds on 26 attempts. Purdue gave up 50 run attempts for 232 yards (4.6 yards per carry). The Boilermakers pass defense allowed a completion percentage of 42.3%, surrendering 132 yards on 11 for 26 passing.
The Purdue Boilermakers average 393.9 yards/game, which is good for 66th in D-1. The Purdue offense has totaled 420 penalty yds on 42 infractions, which ranks them 77th in D-1 in terms of helping out the other team. They average 130.9 yards per game via the rush and have rushed for 916 yards overall. They have thrown 10 interceptions while letting opponents recover 5 fumbles and they have been able to obtain 156 1st downs. Regarding their scoring prowess, the Boilermakers are sitting 100th in college football averaging 22.7 points per game. During the season thus far, the Boilermakers have compiled 1,841 yards via the pass along with holding an average of 263.0 passing yards per game, which ranks 43rd in the country.
The Boilermakers are conceding 27.9 points per contest, which has them sitting 96th in D-1. Purdue has surrendered a total of 1,008 yards on the ground (144.0 yards per game) in addition to 11 touchdowns on the ground so far this season. They have allowed 8 touchdowns via the pass and 229.4 yards per game, which has them sitting 84th in college football. The Boilermakers defense has taken part in 445 plays, which is good for 48th in D-1. Their defense has totaled 2 fumbles recovered and 2 picks over the course of the season. This year, they have surrendered 195 total points.
Who will win tonight's Scarlet Knights/Boilermakers college football game against the spread?
Guy's Pick: Take the Boilermakers +2.5
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Additional Resources:
Purdue Boilermakers - Twitter
Rutgers Scarlet Knights - Twitter