South Carolina Gamecocks vs LSU Tigers Prediction, 10/11/2025 College Football Picks, Best Bets & Odds

Game: South Carolina Gamecocks vs LSU Tigers

Date: Saturday, October 11, 2025

Location: Tiger Stadium in Baton Rouge, LA

TV: SEC Network

Odds/Point Spread: Tigers (-9.5)

Total/Over-Under: 44.5

The LSU Tigers (4-1) will try to beat the South Carolina Gamecocks (3-2) at Tiger Stadium on Saturday, October 11, 2025. South Carolina opens as 9.5-point dogs from oddsmakers. The total is 44.5.

The South Carolina Gamecocks head into this game 3-2 for this season. In their last matchup, the Gamecocks played against the Kentucky Wildcats and notched a win by a score of 35-13. The South Carolina Gamecocks ran the football 48 different times and accrued 178 yards, which is an average of 3.7 yards per carry. Overall, they had 63 plays which gave them 341 yards. South Carolina conceded 10 completions on 19 attempts for a total of 124 yds, and a completion rate of 52.6%. Against the run, the Gamecocks gave up 108 yards on 41 tries, which is an average of 2.6 yards per run allowed.

Regarding putting the ball in the endzone, the South Carolina Gamecocks have an average of 24.8 points per outing. Offensively they're holding an average of 99.8 yards on the ground ranking them 122nd in the country. The Gamecocks have earned 1,543 yards in total this season. When it comes to scoring, South Carolina has compiled 4 touchdowns via the pass and 6 rushing touchdowns. South Carolina has accumulated 86 first downs as a unit, and they have been called for 42 infractions for 347 yds. They have turned the ball over 4 times.

Concerning yards through the air, the Gamecocks have given up 901 yards which ranks them 29th in the country. They have surrendered 180.2 yards per game through the air as well as giving up a completion percentage of 57.0%. Overall, they are conceding 323.4 yards per outing which has them sitting 44th in the country. They have yielded 4 touchdowns via the pass in addition to 5 touchdowns via the ground game. They are allowing teams to run for an average of 3.6 yards per run and 143.2 rushing yards per game this year. During the season, they have given up 716 rushing yards through 5 outings. The Gamecocks are ranked 33rd in the nation regarding their opponents scoring, giving up 18.8 points per game.

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The Tigers come into this game with a record of 4-1 this season. When they last played, the Tigers went home defeated by a final of 24-19 against the Ole Miss Rebels. LSU relinquished 45 run attempts for 166 yds (3.7 yards per rush). The Tigers passing defense conceded a completion percentage of 59.0%, surrendering 314 yards on 23 out of 39 passing. The Tigers finished the game with a total of 254 yards on 56 plays (4.5 yds per play). LSU ran the ball for 2.6 yards per attempt, finishing the game with 57 yards on 22 carries.

The LSU Tigers maintain an average of 364.2 yards per outing, which ranks them 83rd in the nation. The LSU offense has compiled 318 yards of penalties on 36 violations, which is good for 44th in the country in terms of helping out the other team. They have an average of 104.8 yards per game on the ground and have run for 524 yards in total. They have tossed 3 picks while conceding 2 fumbles and they have tallied 110 first downs. In relation to this team's ability to score points, the Tigers currently rank 81st in the nation maintaining an average of 27.0 points per game. Over the course of the season so far, the Tigers have a total of 1,297 yards through the air along with an average of 259.4 throwing yards per contest, which has them sitting 45th in college football.

LSU has given up a total of 422 yards rushing (84.4 yards/game) as well as 3 touchdowns via the rush for the campaign. They have conceded 4 touchdowns from the passing game as well as 208.6 yards per contest, which has them sitting 62nd in college football. Over the course of the season, they have surrendered 61 total points. Their defense has 1 fumble and 7 interceptions on the season. The Tigers defense has participated in 318 plays, which ranks 39th in college football. The Tigers are surrendering 12.2 PPG, ranking them 8th in the nation.

Who will win tonight's Gamecocks/Tigers college football game against the spread?

Josh's Pick: Take the Gamecocks +9.5

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