South Carolina Gamecocks vs Ole Miss Rebels Prediction, 11/1/2025 College Football Picks, Best Bets & Odds

Game: South Carolina Gamecocks vs Ole Miss Rebels

Date: Saturday, November 1, 2025

Location: Vaught-Hemingway Stadium in Oxford, MS

TV: ESPN

Odds/Point Spread: Rebels (-12.5)

Total/Over-Under: 54.5

The South Carolina Gamecocks (3-5) are traveling to Vaught-Hemingway Stadium on Saturday, November 1, 2025 where they will play the Ole Miss Rebels (7-1). Ole Miss opens this contest as 12.5-point favorites. The over/under has been set at 54.5.

The South Carolina Gamecocks come into this matchup with a record of 3-5 this season. In their last contest, the Gamecocks faced the Alabama Crimson Tide and went home with a loss by a final score of 29-22. When all was said and done, they ran 70 plays which totaled 333 yds. The South Carolina Gamecocks ended up running the ball 37 times and accounted for 111 yds, earning them an average of 3.0 yards per carry. In the running game, the Gamecocks conceded 72 yards on 23 attempts, which is 3.1 yards per run allowed. South Carolina conceded 24 pass completions on 43 attempts for 253 yds, and a completion percentage of 55.8%.

Concerning putting points on the board, the South Carolina Gamecocks have an average of 20.4 points per game. As a team they're averaging 107.1 yards rushing which ranks them 121st in the nation. The Gamecocks have racked up 2,417 total yards over the course of this season. With reference to getting in the endzone, South Carolina has earned 6 touchdowns via the pass and 8 rushing touchdowns. South Carolina has compiled 139 1st downs as an offense, and they have been called for 64 infractions for 487 yards. They have turned the ball over 10 different times.

Regarding yards through the air, the Gamecocks are allowing 1,556 yards which ranks them 40th in the country. They have yielded 194.5 yards per game via the pass and allowed a completion percentage of 58.7%. Overall, they are giving up 335.1 yards per outing putting them 39th in Division 1. They have surrendered 9 touchdowns via the pass as well as 8 touchdowns on the ground. The opposition is running for 3.9 yards per tote and 140.6 yards on the ground per game for the season. Overall, they have allowed 1,125 rushing yards through 8 games. The Gamecocks rank 39th in the country in terms of team defense, allowing 21.1 points per game.

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The Rebels head into this game 7-1 this season. For their last game, the Rebels got the victory with a final of 34-26 when they faced the Oklahoma Sooners. Ole Miss rushed for 2.8 yards per tote, finishing the game with 116 yds on 41 carries. The Rebels finished the game with a total of 431 yards and they ran 87 plays (5.0 yds per play). The Rebels pass defense gave up a completion percentage of 53.1%, relinquishing 223 yards on 17 for 32 passing. Ole Miss surrendered 28 run attempts for 136 yds (4.9 yds per rush).

The Ole Miss Rebels average 484.3 yards/contest, which ranks them 10th in Division 1. The Ole Miss offense has accrued 533 yds of penalties on 57 violations, which is good for 25th in Division 1 in terms of giving up free yards. They maintain an average of 178.8 yards per game on the ground and have rushed for 1,430 yards for the season. They have given away 5 interceptions while conceding 3 fumbles and they have been able to obtain 197 1st downs. Concerning how much they score, the Rebels are sitting 19th in D-1 by scoring 37.0 points per outing. During this campaign to this point, the Rebels have racked up 2,444 yards through the air in addition to an average of 305.5 passing yards per game, which has them sitting 8th in college football.

The Rebels are conceding 23.0 PPG, which has them ranked 54th in Division 1. Ole Miss has allowed a total of 1,303 rushing yards (162.9 yards per outing) in addition to 11 touchdowns via the rush on the year. They have surrendered 11 touchdowns through the air and 199.0 yards per outing, which has them in 41st in college football. The Rebels defense has been on the field for 525 plays, which is 83rd in D-1. They have totaled 2 fumbles recovered and 3 interceptions so far this year. This season, they have given up 184 total points.

Who will win tonight's Gamecocks/Rebels college football game against the spread?

Josh's Pick: Take the Gamecocks +12.5

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