Southern Miss Golden Eagles vs Louisiana Ragin' Cajuns Prediction, 10/18/2025 College Football Picks, Best Bets & Odds

Game: Southern Miss Golden Eagles vs Louisiana Ragin' Cajuns

Date: Saturday, October 18, 2025

Location: Cajun Field in Lafayette, LA

TV: ESPN+

Odds/Point Spread: Ragin' Cajuns (+4.0)

Total/Over-Under: 54.5

Cajun Field is the location where the Louisiana Ragin' Cajuns (2-4) will compete against the Southern Miss Golden Eagles (4-2) on Saturday, October 18, 2025. Louisiana opens this game as 4.0-point underdogs from oddsmakers. The betting total comes in at 54.5.

The Southern Miss Golden Eagles head into this game 4-2 for this season. In their last game, the Golden Eagles played the Georgia Southern Eagles and earned the victory with a final of 38-35. In the running game, the Golden Eagles gave up 82 yds on 34 tries, which is an average of 2.4 yards per run allowed. Southern Miss surrendered 24 completions on 43 attempts for a total of 313 yards, and a completion percentage of 55.8%. In the game, they ran 76 plays which converted into 421 yards. The Southern Miss Golden Eagles ran the rock 48 times and accrued 184 yards, which had them averaging 3.8 yds per attempt.

Concerning putting points on the board, the Southern Miss Golden Eagles have an average of 32.2 points per contest. As a team they average 147.0 yards in the run game giving them a rank of 80th in the nation. The Golden Eagles have tallied 2,365 yards in total over the course of this season. When it comes to notching touchdowns, Southern Miss has earned 13 passing touchdowns and 9 rushing touchdowns. Southern Miss has a total of 140 first downs offensively, and they have been called for 44 penalties for 350 yards. They have surrendered the ball 5 times.

When it comes to yards through the air, the Golden Eagles are allowing 1,464 yards which has them sitting in 103rd in D-1. They have conceded 244.0 yards per outing via the pass and conceding a completion percentage of 60.5%. Overall, they are conceding 396.8 yards per contest which puts them 106th in Division 1. They have conceded 5 touchdowns via the pass as well as 15 touchdowns pounding the rock. Opposing teams are running for an average of 3.7 yards per rush and 152.8 rushing yards per contest this season. During this campaign, they have allowed 917 yards via the ground game in 6 games. The Golden Eagles are ranked 95th in college football when it comes to the opposition scoring, conceding 27.7 points per game.

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The Ragin' Cajuns head into this matchup 2-4 for this year. When they last stepped on the field, the Ragin' Cajuns took a defeat with a final score of 24-14 when they faced the James Madison Dukes. Louisiana ran the football for 1.6 yds per carry, totaling 45 yards on 28 attempts. The Ragin' Cajuns finished the game with 288 yds while they ran 57 plays (5.1 yds per play). The Ragin' Cajuns pass defense conceded a completion rate of 65.0%, surrendering 290 yards on 26 out of 40 through the air. Louisiana allowed 41 run attempts for 187 yards (4.6 yds per rush).

In relation to their ability to score points, the Ragin' Cajuns currently sit 86th in Division 1 with 25.8 PPG. The Louisiana Ragin' Cajuns hold an average of 326.8 yards per outing, which ranks them 113th in Division 1. The Louisiana offense has totaled 274 penalty yards on 35 infractions, which ranks them 84th in the nation in terms of giving up free yards. They have thrown 6 interceptions while letting opponents recover 1 fumbles and they have obtained 107 first downs. During this campaign to this point, the Ragin' Cajuns have a total of 855 passing yards as well as holding an average of 142.5 passing yards per game, ranking them 129th in D-1. They average 184.3 yards per game on the ground and have run for 1,106 yards in total.

The Ragin' Cajuns are relinquishing 30.8 points per contest, which has them 117th in the nation. Louisiana has allowed a total of 1,295 yards rushing (215.8 yards per outing) in addition to 13 touchdowns on the ground this year. They have conceded 9 touchdowns through the air and 198.2 yards per game, ranking them 44th in Division 1. The Ragin' Cajuns defense has been on the field for 433 plays, ranking them 114th in the country. They have tallied 4 fumbles recovered and 4 interceptions on the season. This year, they have relinquished 185 points.

Who will win tonight's Golden Eagles/Ragin' Cajuns college football game against the spread?

Josh's Pick: Take the Ragin' Cajuns +4.0

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