Utah Utes vs Wyoming Cowboys Prediction, 9/13/2025 College Football Picks, Best Bets & Odds

Game: Utah Utes vs Wyoming Cowboys

Date: Saturday, September 13, 2025

Location: War Memorial Stadium in Laramie, WY

TV: CBSSN

Odds/Point Spread: Cowboys (+23.5)

Total/Over-Under: 48

War Memorial Stadium is the site where the Wyoming Cowboys (2-0) will attempt to defeat the Utah Utes (2-0) on Saturday, September 13, 2025. Utah opens this matchup as 23.5-point favorites. The total has been set at 48.

The Utah Utes come into this game with a record of 2-0 for this year. The last time they stepped onto the field, the Utes took the field against the Cal Poly Mustangs and went home with a win by a final score of 63-9. In all, they ran 73 plays which gave them 518 yds. The Utah Utes ran the rock 46 times and compiled 273 yards, earning them an average of 5.9 yards per tote. On the ground, the Utes gave up 65 yards on 28 tries, which is 2.3 yards per rush surrendered. Utah relinquished 15 pass completions on 30 tries for a total of 158 yds, and a completion percentage of 50.0%.

The Utes have racked up 1,010 total yards for the year. With reference to getting in the endzone, Utah has amassed 5 touchdowns via the pass and 9 rushing touchdowns. They have yet to turn the ball over. Utah has earned 54 1st downs offensively, and they have been called for 10 infractions for 80 yards. As a team they're averaging 279.5 yards on the ground which is 8th in the nation. When talking about putting the ball in the endzone, the Utah Utes have an average of 53.0 points per contest.

The Utes sit in 21st in the country concerning team defense, giving up 9.5 points per game. Opposing teams are running for an average of 2.7 yards per run and 74.5 rushing yards per contest on the campaign. For the year, they have given up 149 yards via the running game in 2 games. Regarding yards via the pass, the Utes are allowing 294 yards which has them ranked 35th in the country. They have conceded 147.0 yards per game via the pass as well as giving up a completion percentage of 50.0%. Overall, they are giving up 221.5 yards per contest putting them 19th in D-1. They have allowed 1 touchdown through the air.

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The Cowboys head into this game 2-0 this year. The last time they took the gridiron, the Cowboys got the victory with a final of 31-7 when they faced the Northern Iowa Panthers. Wyoming rushed the ball for 5.1 yds per carry, finishing the contest with 189 yds on 37 attempts. The Cowboys finished with 379 yds while they ran 63 plays (6.0 yards per play). The Cowboys passing defense conceded a completion percentage of 55.2%, relinquishing 111 yds on 16 for 29 through the air. Wyoming conceded 29 run attempts for 59 yds (2.0 yds per rush).

The Wyoming Cowboys average 402.5 yards/game, which ranks them 70th in Division 1. The Wyoming offense has racked up 155 yards of penalties on 20 violations, which is good for 8th in the country in terms of hurting your team. They are averaging 177.5 yards per game via the rush and have rushed for 355 yards for this year. They have earned 44 1st downs. In relation to their ability to score points, the Cowboys are sitting 106th in the country maintaining an average of 20.5 PPG. For the year to this point, the Cowboys have earned 450 yards through the air in addition to holding an average of 225.0 throwing yards per outing, putting them at 73rd in college football.

The Cowboys are allowing 3.5 points per game, which has them sitting 3rd in the nation. Wyoming has surrendered a total of 148 yards via the ground game (74.0 yards per game) and 1 touchdown via the rush this year. They have allowed 0 touchdowns through the air as well as 125.0 yards per contest, ranking them 17th in the country. The Cowboys defense has participated in 124 plays, which ranks them 47th in Division 1. Their defense has totaled 0 fumbles and 3 interceptions for the season.

Who will win tonight's Utes/Cowboys college football game against the spread?

Guy's Pick: Take the Cowboys +23.5

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