UTSA Roadrunners vs USF Bulls Prediction, 11/6/2025 College Football Picks, Best Bets & Odds

Game: UTSA Roadrunners vs USF Bulls

Date: Thursday, November 6, 2025

Location: Raymond James Stadium in Tampa, FL

TV: ESPN

Odds/Point Spread: Bulls (-13.5)

Total/Over-Under: 68.5

The USF Bulls (6-2) will try to beat the UTSA Roadrunners (4-4) at Raymond James Stadium on Thursday, November 6, 2025. USF opens as 13.5-point favorites. The betting total comes in at 68.5.

The UTSA Roadrunners step onto the field holding a record of 4-4 this year. The last time they took the field, the Roadrunners faced the Tulane Green Wave and earned the victory with a final of 48-26. In the running game, the Roadrunners gave up 135 yards on 25 tries, which is an average of 5.4 yards per rush surrendered. UTSA surrendered 21 completions on 36 tries for a total of 299 yards, and a completion percentage of 58.3%. At the end of the game, they had 69 plays for 523 yards. The UTSA Roadrunners ran the football 35 different times and tallied 132 yards, earning them an average of 3.8 yds per attempt.

In terms of scoring, the UTSA Roadrunners are sitting at 34.0 points per contest. As a team they're holding an average of 178.3 yards in the run game which has them sitting 47th in the country. The Roadrunners have earned 3,217 total yards over the course of this season. When it comes to scoring, UTSA has earned 19 touchdowns through the air and 14 touchdowns via the ground. UTSA has accrued 159 first downs offensively, and they have committed 60 infractions for 572 yards. They have turned the ball over 7 times.

When talking about yards via the pass, the Roadrunners have given up 2,027 yards which ranks them 94th in D-1. They have conceded 253.4 yards per game through the air in addition to allowing a completion percentage of 62.4%. During this campaign, they are conceding 401.6 yards/game putting them at 102nd in D-1. They have surrendered 19 touchdowns via the pass and 11 touchdowns pounding the rock. They are allowing an average of 4.2 yards per rush and 148.3 yards on the ground per contest for the season. For the year, they have allowed 1,186 running yards through 8 games. The Roadrunners are ranked 109th in D-1 regarding their opponents scoring, conceding 30.3 points per game.

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The Bulls step onto the field holding a record of 6-2 for this season. When they last stepped on the field, the Bulls took a defeat with a final score of 34-31 against the Memphis Tigers. USF ran the ball for 7.8 yards per tote, finishing with 295 yds on 38 attempts. The Bulls finished with a total of 564 yds on 82 plays (6.9 yards per play). The Bulls secondary gave up a completion percentage of 62.2%, surrendering 321 yds on 28 out of 45 through the air. USF relinquished 34 run attempts for 129 yards (3.8 yds per carry).

Regarding how much they score, the Bulls are ranking 6th in D-1 by scoring 40.4 points per contest. The USF Bulls are averaging 487.0 yards/contest, which has them sitting 7th in the nation. The USF offense has accrued 510 yards of penalties on 53 violations, which has them sitting 69th in Division 1 in terms of hurting your team. They have tossed 6 interceptions while letting opponents recover 5 fumbles and they have tallied 193 1st downs. For the season thus far, the Bulls currently sit at 2,092 passing yards as well as an average of 261.5 passing yards per game, which has them ranked 31st in the nation. They are averaging 225.5 yards per game via the rush and have run for 1,804 yards for the year.

USF has yielded a total of 919 yards on the ground (114.9 yards per outing) in addition to 12 touchdowns on the ground this season. They have allowed the opposition 12 touchdowns through the air as well as 272.4 yards/game, which puts them in 129th in Division 1. In total, they have relinquished 195 points in total. They have earned 7 fumbles and 10 interceptions so far this year. The Bulls defense has taken the field for 603 plays, which has them sitting 110th in the nation. The Bulls are conceding 24.4 PPG, which has them ranked 70th in D-1.

Who will win tonight's Roadrunners/Bulls college football game against the spread?

Josh's Pick: Take the Bulls -13.5

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