Vanderbilt Commodores vs Alabama Crimson Tide Prediction, 10/4/2025 College Football Picks, Best Bets & Odds

Game: Vanderbilt Commodores vs Alabama Crimson Tide

Date: Saturday, October 4, 2025

Location: Bryant-Denny Stadium in Tuscaloosa, AL

TV: ABC

Odds/Point Spread: Crimson Tide (-9.5)

Total/Over-Under: 56.5

Bryant-Denny Stadium is the location where the Alabama Crimson Tide (3-1) will meet the Vanderbilt Commodores (5-0) on Saturday, October 4, 2025. Vanderbilt opens as 9.5-point underdogs. The over/under comes in at 56.5.

The Vanderbilt Commodores come into this matchup with a record of 5-0 for this year. The last time they stepped onto the field, the Commodores stepped onto the field against the Utah State Aggies and walked away with a win by a score of 55-35. In the game, they ran 65 plays which converted into 543 yards. The Vanderbilt Commodores ended up running the ball 30 different times and accounted for 222 yards, which earned them an average of 7.4 yards per carry. When it came to stopping the run, the Commodores conceded 119 yds on 25 tries, which averages out to 4.8 yards per run allowed. Vanderbilt relinquished 28 completions on 38 attempts for 274 yds, and a completion rate of 73.7%.

The Commodores have earned 2,472 total yards over the course of this year. When it comes to getting in the endzone, Vanderbilt has earned 14 passing touchdowns and 18 rushing touchdowns. They have turned the ball over 4 different times. Vanderbilt has accrued 131 first downs as a unit, and they have committed 39 penalties for 356 yds. As a unit they have an average of 223.4 yards rushing ranking them 18th in college football. In terms of putting the ball in the endzone, the Vanderbilt Commodores are averaging 49.0 PPG.

Concerning passing yardage, the Commodores are giving up 995 yards which ranks them 74th in Division 1. They are allowing 199.0 yards per contest via the pass and giving up a completion percentage of 65.5%. In total, they have given up 278.8 yards/game putting them 21st in the country. They have given up 9 touchdowns through the air in addition to 2 touchdowns on the ground. They are allowing an average of 3.0 yards per run and 79.8 rushing yards per game on the campaign. For the season, they have conceded 399 running yards through 5 outings. The Commodores sit in 31st in the nation regarding team defense, conceding 17.2 points per game.

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The Crimson Tide head into this game 3-1 for this year. When they last stepped on the field, the Crimson Tide got the victory with a final of 24-21 when they played the Georgia Bulldogs. Alabama relinquished 33 attempts on the ground for 227 yds (6.9 yards per rush). The Crimson Tide passing defense gave up a completion percentage of 65.0%, relinquishing 130 yards on 13 out of 20 passing. The Crimson Tide finished the contest with a total of 397 yards and they ran 77 plays (5.2 yards per play). Alabama rushed for 3.1 yards per carry, finishing with a total of 117 yards on 38 carries.

The Alabama Crimson Tide are averaging 443.8 yards per outing, which has them sitting 36th in D-1. The Alabama offense has 198 yds of penalties on 24 infractions, which is 93rd in the country in terms of making mistakes. They are averaging 122.0 run yards per game and have run for 488 yards for the season. They have thrown no interceptions while conceding no fumbles and they have been able to record 94 1st downs. When looking at putting points on the board, the Crimson Tide rank 26th in Division 1 maintaining an average of 38.0 points per game. During this campaign to this point, the Crimson Tide currently sit at 1,287 yards via the pass together with an average of 321.8 throwing yards per contest, which is ranked 10th in the country.

The Crimson Tide are allowing 16.5 PPG, which has them ranked 29th in college football. Alabama has surrendered a total of 642 rushing yards (160.5 yards/game) as well as 6 touchdowns via the rush for the season. They have surrendered 2 touchdowns through the air and 113.5 yards/outing, ranking them 2nd in the country. The Crimson Tide defense has been on the field for 217 plays, which ranks them 2nd in the nation. Their defense has totaled 4 fumbles recovered and 3 interceptions for the year. This season, they have conceded 66 points.

Who will win tonight's Commodores/Crimson Tide college football game against the spread?

Tony's Pick: Take the Crimson Tide -9.5

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