Colorado Buffaloes vs Baylor Bears Prediction, 9/26/2026 College Football Picks, Best Bets & Odds

Game: Colorado Buffaloes vs Baylor Bears

Date: Saturday, September 26, 2026

Location: McLane Stadium in Waco, TX

TV: ESPN2

Odds/Point Spread: Bears (-10.5)

Total/Over-Under: 54.5

The Baylor Bears (2-1) will go up against the Colorado Buffaloes (2-1) at McLane Stadium on Saturday, September 26, 2026. Colorado opens this contest as 10.5-point underdogs. The total comes in at 54.5.

The Colorado Buffaloes come into this game with a record of 2-1 this season. The last time they stepped onto the field, the Buffaloes faced the Northwestern Wildcats and took a loss by a score of 41-7. Against the run, the Buffaloes gave up 182 yds on 51 attempts, which is an average of 3.6 yards per run surrendered. Colorado allowed 17 pass completions on 22 attempts for a total of 241 yds, and a completion percentage of 77.3%. When all was said and done, they ran 62 plays which gave them a total of 348 yds. The Colorado Buffaloes ran the football 33 times and accrued 180 yards, which is an average of 5.5 yards per attempt.

When talking about getting in the endzone, the Colorado Buffaloes are averaging 24.3 points per contest. Offensively they're averaging 181.0 yards rushing which has them sitting 49th in D-1. The Buffaloes have tallied 1,233 total yards this season. When it comes to getting the ball in the endzone, Colorado has amassed 6 passing touchdowns and 4 touchdowns via the ground. Colorado has tallied 63 1st downs as a team, and they have been flagged for 28 penalties for 247 yds. They have turned the football over 6 times.

Regarding yards through the air, the Buffaloes have conceded 728 yards which ranks them 109th in D-1. They have allowed 242.7 yards per contest through the air as well as conceding a completion percentage of 57.2%. For the year, they are conceding 361.0 yards/outing ranking them 89th in college football. They have yielded 6 touchdowns by air and 2 touchdowns via the ground game. The opposition is running for an average of 3.2 yards per rushing attempt and 118.3 rushing yards per contest on the season. In total, they have conceded 355 yards via the running game in 3 contests. The Buffaloes are sitting in 91st in Division 1 regarding the opposition scoring, conceding 25.0 points per game.

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The Bears come into this matchup with a record of 2-1 for this season. When they last played, the Bears got the win with a final of 36-19 against the Louisiana Tech Bulldogs. The Bears ended up finishing with 418 yds while they ran 68 plays (6.1 yards per play). Baylor ended up running for 3.8 yds per attempt, finishing with a total of 165 yds on 44 attempts. Baylor allowed 34 rush attempts for 139 yds (4.1 yds per rush). The Bears pass defense conceded a completion percentage of 56.8%, surrendering 223 yards on 25 for 44 passing.

Concerning their scoring prowess, the Bears currently sit 66th in the country averaging 32.0 PPG. The Baylor Bears have an average of 468.7 yards per contest, which has them sitting 33rd in college football. The Baylor offense has accrued 215 yds of penalties on 24 infractions, which is good for 32nd in D-1 in terms of helping out the other team. They have tossed 4 interceptions while conceding 3 fumbles and they have tallied 81 first downs. For the year so far, the Bears currently have a total of 919 passing yards together with an average of 306.3 passing yards per contest, ranking them 19th in the nation. They maintain an average of 162.3 yards via the ground game and have run for 487 yards overall.

Baylor has given up a total of 305 yards via the ground game (101.7 yards per game) in addition to 4 touchdowns on the ground on the year. They have allowed 1 touchdowns through the air as well as 185.3 yards per game, ranking them 53rd in the nation. This year, they have surrendered 39 points in total. Their defense has earned 2 fumbles recovered and 4 interceptions on the campaign. The Bears defense has participated in 206 plays, which ranks 101st in college football. The Bears are relinquishing 13.0 points per contest, which has them sitting 22nd in the nation.

Who will win tonight's Buffaloes/Bears college football game against the spread?

Guy's Pick: Take the Bears -10.5

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