Michigan State Spartans vs Notre Dame Fighting Irish Prediction, 9/19/2026 College Football Picks, Best Bets & Odds

Game: Michigan State Spartans vs Notre Dame Fighting Irish

Date: Saturday, September 19, 2026

Location: Notre Dame Stadium in Notre Dame, IN

TV: NBC

Odds/Point Spread: Fighting Irish (-30.5)

Total/Over-Under: 52

The Notre Dame Fighting Irish (2-0) will try to beat the Michigan State Spartans (2-0) at Notre Dame Stadium on Saturday, September 19, 2026. Michigan State opens this matchup as 30.5-point dogs from oddsmakers. The total is 52.

The Michigan State Spartans step onto the field holding a record of 2-0 for this season. In their last game, the Spartans took on the Eastern Michigan Eagles and took home the win by a score of 35-7. The Michigan State Spartans ended up running the ball 45 different times and accrued 258 yards, which came out to an average of 5.7 yards per tote. On the day, they had 71 plays which gave them a total of 472 yards. Michigan State conceded 16 completions on 26 tries for a total of 118 yds, and a completion rate of 61.5%. Against the run, the Spartans conceded 101 yards on 26 tries, which is 3.9 yds per run allowed.

When it comes to getting in the endzone, the Michigan State Spartans are averaging 32.5 points per outing. As a team they're averaging 204.0 yards on the ground ranking them 40th in the nation. The Spartans have tallied 869 total yards over the course of this season. With reference to notching touchdowns, Michigan State has totaled 3 touchdowns via the pass and 4 rushing touchdowns. Michigan State has amassed 50 first downs, and they have been hurt by 8 infractions for 75 yds. They have surrendered the ball 1 time.

The Spartans rank 38th in D-1 when it comes to the opposition scoring, giving up 13.5 points per game. They are allowing teams to run for an average of 3.9 yards per rush and 89.0 rushing yards per game on the year. Overall, they have given up 178 running yards through 2 contests. When talking about passing yards, the Spartans have given up 314 yards which puts them in 37th in D-1. They have allowed 157.0 yards per game via the pass as well as allowing a completion percentage of 59.6%. Overall, they are allowing 246.0 yards per game ranking them 24th in the nation. They have conceded 2 touchdowns through the air and 2 touchdowns running the ball.

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The Fighting Irish head into this game 2-0 for this season. When they last stepped on the gridiron, the Fighting Irish got the victory with a final of 52-0 when they played the Rice Owls. The Fighting Irish finished with a total of 478 yds on 65 plays (7.4 yards per play). Notre Dame ended up running for 3.7 yds per carry, finishing with a total of 118 yards on 32 attempts. Notre Dame relinquished 34 attempts on the ground for 64 yds (1.9 yards per rush). The Fighting Irish pass defense allowed a completion rate of 66.7%, surrendering 64 yards on 8 for 12 through the air.

The Notre Dame Fighting Irish hold an average of 414.0 yards per contest, which has them ranked 67th in college football. The Notre Dame offense has racked up 61 yds of penalties on 6 infractions, which ranks 132nd in Division 1 in terms of hurting your team. They maintain an average of 114.5 yards per game via the ground game and have run for 229 yards for the year. They have given away no picks while surrendering no fumbles and they have been able to earn 44 first downs. When looking at how much they score, the Fighting Irish currently sit 23rd in the country maintaining an average of 46.5 points per contest. During the season thus far, the Fighting Irish have thrown for a total of 599 passing yards as well as an average of 299.5 passing yards per game, ranking them 26th in Division 1.

Notre Dame has given up a total of 131 rushing yards (65.5 yards per outing) in addition to 0 touchdown via the rush this season. They have allowed 1 touchdown through the air in addition to 140.5 yards/game, which has them ranked 23rd in D-1. They have totaled 5 fumbles and 1 pick this season. The Fighting Irish defense has taken the field for 107 plays, which has them sitting 12th in the country. The Fighting Irish are surrendering 6.5 points per game, which has them 8th in college football.

Who will win tonight's Spartans/Fighting Irish college football game against the spread?

Josh's Pick: Take the Fighting Irish -30.5

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