Oklahoma State Cowboys vs Iowa State Cyclones Prediction, 10/31/2026 College Football Picks, Best Bets & Odds

Game: Oklahoma State Cowboys vs Iowa State Cyclones

Date: Saturday, October 31, 2026

Location: Jack Trice Stadium in Ames, IA

TV: SEC Network

Odds/Point Spread: Cyclones (+7.5)

Total/Over-Under: 57

The Iowa State Cyclones (3-4) will take on the Oklahoma State Cowboys (5-2) at Jack Trice Stadium on Saturday, October 31, 2026. Oklahoma State opens this game as 7.5-point favorites from Vegas oddsmakers. The over/under is 57.

The Oklahoma State Cowboys head into this matchup 5-2 for this season. The last time they stepped onto the field, the Cowboys played the Colorado Buffaloes and notched a win by a score of 57-24. The Oklahoma State Cowboys rushed the ball a total of 38 different times and recorded 188 yds, which had them averaging 4.9 yards per attempt. When all was said and done, they tallied 76 plays which converted into 598 yards. Oklahoma State conceded 22 pass completions on 32 tries for 343 yards, and a completion rate of 68.8%. When it came to the battle of the line of scrimmage, the Cowboys gave up 56 yds on 30 tries, which is an average of 1.9 yards per rush surrendered.

The Cowboys have earned 3,704 total yards for the year. In terms of scoring touchdowns, Oklahoma State has earned 21 touchdowns through the air and 10 touchdowns via the ground. They have turned the ball over 11 times. Oklahoma State has accrued 185 first downs offensively, and they have been flagged for 39 penalties for 363 yards. Offensively they average 188.1 yards via the ground game ranking them 38th in college football. When it comes to scoring, the Oklahoma State Cowboys have an average of 40.0 PPG.

The Cowboys rank 64th in college football regarding team defense, giving up 23.7 PPG. They are allowing 3.7 yards per rush and 137.6 rushing yards per contest for the year. For the year, they have conceded 963 yards on the ground through 7 outings. In terms of yards through the air, the Cowboys have conceded 1,585 yds which has them sitting in 78th in Division 1. They are allowing 226.4 yards per contest via the pass as well as giving up a completion percentage of 63.8%. During this campaign, they have relinquished 364.0 yards per game which has them ranked 73rd in college football. They have relinquished 14 touchdowns by air as well as 7 touchdowns via the ground game.

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The Cyclones head into this game 3-4 for this season. The last time they took the gridiron, the Cyclones took a defeat with a final score of 39-3 when they played the Arizona Wildcats. Iowa State allowed 36 rushing attempts for 141 yards (3.9 yds per rush). The Cyclones pass defense allowed a completion percentage of 81.1%, surrendering 336 yards on 30 out of 37 through the air. The Cyclones finished the contest with a total of 221 yds and they ran 58 plays (3.8 yards per play). Iowa State ran the ball for 1.7 yds per carry, finishing with 52 yards on 31 attempts.

In relation to the points being put on the board, the Cyclones are sitting 90th in college football scoring 25.9 points per contest. The Iowa State Cyclones have an average of 339.9 yards per outing, which ranks them 108th in the nation. The Iowa State offense has totaled 325 yds of penalties on 38 infractions, which is 118th in Division 1 in terms of giving up free yards. They have thrown 4 picks while losing 2 fumbles and they have recorded 129 first downs. During the season to this point, the Cyclones have compiled 1,238 passing yards along with an average of 176.9 passing yards per outing, which ranks 123rd in Division 1. They are averaging 163.0 run yards per game and have rushed for 1,141 yards for the season.

The Cyclones are conceding 24.1 PPG, which has them 70th in the country. Iowa State has surrendered a total of 1,064 yards via the ground game (152.0 yards per game) and 12 touchdowns on the ground on the season. They have allowed the opposition 9 touchdowns through the air as well as 218.1 yards/outing, ranking them 86th in college football. The Cyclones defense has been on the field for 435 plays, which is good for 25th in the nation. Their defense has compiled 6 fumbles and 2 picks so far this year. Overall, they have allowed 169 points in total.

Who will win tonight's Cowboys/Cyclones college football game against the spread?

Josh's Pick: Take the Cyclones +7.5

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