Oregon Ducks vs Oklahoma State Cowboys Prediction, 9/12/2026 College Football Picks, Best Bets & Odds

Game: Oregon Ducks vs Oklahoma State Cowboys

Date: Saturday, September 12, 2026

Location: Boone Pickens Stadium in Stillwater, OK

TV: ESPN+

Odds/Point Spread: Cowboys (+22.0)

Total/Over-Under: 56.5

The Oklahoma State Cowboys (0-1) will take on the Oregon Ducks (1-0) at Boone Pickens Stadium on Saturday, September 12, 2026. Oregon opens as 22-point favorites from oddsmakers. The over/under has been set at 56.5.

The Oregon Ducks come into this game with a record of 1-0 for this season. In their last game, the Ducks took the field against the Boise State Broncos and walked away with a win by a score of 34-27. The Oregon Ducks ran the football 25 times and had 119 yards, which came out to an average of 4.8 yds per carry. On the day, they ran 63 plays which gave them 497 yards. Oregon relinquished 15 pass completions on 29 tries for 181 yards, and a completion percentage of 51.7%. Against the rush, the Ducks conceded 93 yards on 36 tries, which is an average of 2.6 yards per run allowed.

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When it comes to getting in the endzone, the Oregon Ducks have an average of 34.0 points per game. Offensively they are averaging 119.0 yards rushing which is 99th in D-1. The Ducks have attained 497 yards in total for the year. In terms of scoring touchdowns, Oregon has totaled 3 touchdowns via the pass and 1 touchdown on the ground. Oregon has accrued 18 1st downs as a team, and they have committed 10 penalties for 90 yards. They have turned the football over 1 time.

The Ducks are sitting in 100th in the country concerning the opposition scoring, conceding 27.0 points per game. They are giving up an average of 2.6 yards per rush and 93.0 yards on the ground per contest on the season. Over the course of this year, they have conceded 93 rushing yards through 1 contest. In terms of passing yards, the Ducks have conceded 181 yds which puts them in 60th in Division 1. They are giving up 181.0 yards per game through the air and allowed a completion percentage of 51.7%. In total, they are surrendering 274.0 yards/game putting them at 54th in Division 1. They have yielded 3 touchdowns through the air and no touchdowns running the ball.

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The Cowboys come into this game with a record of 0-1 this year. The last time they took the field, the Cowboys took a loss by a score of 24-10 against the Tulsa Golden Hurricane. The Cowboys finished the contest with a total of 368 yds while they ran 86 plays (4.3 yds per play). Oklahoma State rushed for 3.4 yds per attempt, totaling 127 yards on 37 carries. Oklahoma State relinquished 33 rushing attempts for 134 yards (4.1 yards per carry). The Cowboys secondary conceded a completion rate of 70.8%, relinquishing 227 yds on 17 for 24 through the air.

In relation to this team's ability to score points, the Cowboys are 123rd in D-1 with 10.0 points per outing. The Oklahoma State Cowboys average 368.0 yards per contest, which is good for 89th in the nation. The Oklahoma State offense has racked up 59 penalty yds on 6 violations, which ranks them 85th in D-1 in terms of helping out the opposition. They have given away 2 picks while conceding 2 fumbles and they have earned 27 first downs. Over the course of the season thus far, the Cowboys have earned 241 yards through the air. They are averaging 127.0 yards via the ground game.

The Cowboys are relinquishing 24.0 points per contest, which has them ranked 98th in the country. Oklahoma State has allowed a total of 134 yards rushing as well as 2 touchdowns by way of the ground game for the campaign. They have surrendered 1 touchdown through the air in addition to 227.0 yards per outing, which has them sitting 91st in the nation. The Cowboys defense has participated in 57 plays, which is 41st in college football. They have compiled no fumbles and 1 interception so far this season.

Who will win tonight's Ducks/Cowboys college football game against the spread?

Josh's Pick: Take the Cowboys +22.0

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