Free College Football Picks: Today's Expert Picks Against the Spread, College Football Best Bets, Predictions and Parlays.

UNLV Rebels vs Miami RedHawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The UNLV Rebels (3-0) are headed to Yager Stadium on Saturday, September 20, 2025 where they will try to defeat the Miami RedHawks (0-2). Miami opens this contest as 2.5-point dogs. The total comes in at 49. This matchup report includes Vegas odds and a free college football prediction for tonight.

Arkansas Razorbacks vs Memphis Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Memphis Tigers (3-0) welcome the Arkansas Razorbacks (2-1) at Simmons Bank Liberty Stadium on Saturday, September 20, 2025. Arkansas opens this contest as 7.5-point favorites from Vegas oddsmakers. The betting total comes in at 62.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

NC State Wolfpack vs Duke Blue Devils Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Wallace Wade Stadium is the site where the Duke Blue Devils (1-1) will try to defeat the NC State Wolfpack (3-0) on Saturday, September 20, 2025. Duke opens as 3.5-point favorites. The over/under has been set at 58. This matchup report includes Vegas odds and a free college football prediction for tonight.

Oregon State Beavers vs Oregon Ducks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Oregon State Beavers (0-3) are hitting the road to Autzen Stadium on Saturday, September 20, 2025 where they will take on the Oregon Ducks (3-0). Oregon opens this game as 35.0-point favorites. The betting total comes in at 57.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Coastal Carolina Chanticleers vs South Alabama Jaguars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Hancock Whitney Stadium is the location where the South Alabama Jaguars (1-2) will attempt to defeat the Coastal Carolina Chanticleers (1-2) on Saturday, September 20, 2025. South Alabama opens as 14.5-point favorites from Vegas oddsmakers. The betting total is set at 50.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Nevada Wolf Pack vs Western Kentucky Hilltoppers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Nevada Wolf Pack (1-2) are en route to Houchens Industries on Saturday, September 20, 2025 where they will attempt to defeat the Western Kentucky Hilltoppers (2-1). Western Kentucky opens this contest as 10.5-point favorites. The total comes in at 55.5. This games report has current odds, betting predictions, and free picks against the spread.

Stanford Cardinal vs Virginia Cavaliers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Virginia Cavaliers (2-1) welcome the Stanford Cardinal (0-2) at Scott Stadium on Saturday, September 20, 2025. Stanford opens as 15.0-point dogs from Vegas oddsmakers. The total is 49. This games report has current odds, betting predictions, and free picks against the spread.

Georgia State Panthers vs Vanderbilt Commodores Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

FirstBank Stadium is the site where the Vanderbilt Commodores (3-0) will take on the Georgia State Panthers (1-2) on Saturday, September 20, 2025. Georgia State opens this game as 26.5-point underdogs. The total is 53.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Texas Tech Red Raiders vs Utah Utes Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Utah Utes (3-0) are hosting the Texas Tech Red Raiders (3-0) at Rice-Eccles Stadium on Saturday, September 20, 2025. Texas Tech opens as 4.0-point underdogs. The total comes in at 57. This report includes betting odds and our expert football picks for todays game.

Rice Owls vs Charlotte 49ers Prediction, 9/18/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Jerry Richardson Stadium is the location where the Charlotte 49ers (1-2) will play the Rice Owls (2-1) on Thursday, September 18, 2025. Charlotte is 2.5-point underdogs. The total comes in at 42.5. This matchup report includes college football odds, predictions, and a free pick against the spread.

Washington Huskies vs Washington State Cougars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Washington Huskies (2-0) are en route to Martin Stadium on Saturday, September 20, 2025 where they will attempt to defeat the Washington State Cougars (2-1). Washington opens this matchup as 20.0-point favorites from oddsmakers. The total is set at 53. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

West Virginia Mountaineers vs Kansas Jayhawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Kansas Jayhawks (2-1) will take on the West Virginia Mountaineers (2-1) at David Booth Kansas Memorial Stadium on Saturday, September 20, 2025. West Virginia opens this game as 11.5-point underdogs. The total comes in at 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Sam Houston Bearkats vs Texas Longhorns Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Sam Houston Bearkats (0-3) are en route to DKR-Texas Memorial Stadium on Saturday, September 20, 2025 where they will try to defeat the Texas Longhorns (2-1). Sam Houston is 41.0-point dogs from oddsmakers. The total comes in at 51.5. This report has odds and your NCAA football predictions for todays game against the spread.

Louisiana Ragin' Cajuns vs Eastern Michigan Eagles Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Louisiana Ragin' Cajuns (1-2) are on their way to Rynearson Stadium on Saturday, September 20, 2025 where they will try to defeat the Eastern Michigan Eagles (0-3). Louisiana opens this contest as 3.0-point favorites from oddsmakers. The betting total comes in at 52. This games report has current odds, betting predictions, and free picks against the spread.

Toledo Rockets vs Western Michigan Broncos Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Western Michigan Broncos (0-3) will compete against the Toledo Rockets (2-1) at Waldo Stadium on Saturday, September 20, 2025. Western Michigan opens this game as 14.0-point underdogs. The betting total comes in at 50.5. This report has odds and your NCAA football predictions for todays game against the spread.

Michigan State Spartans vs USC Trojans Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Michigan State Spartans (3-0) are on their way to Los Angeles Memorial Coliseum on Saturday, September 20, 2025 where they will try to beat the USC Trojans (3-0). Michigan State opens this game as 17.0-point dogs. The betting total comes in at 56. This matchup report includes odds, betting predictions and a free pick against the spread.

Purdue Boilermakers vs Notre Dame Fighting Irish Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Purdue Boilermakers (2-1) are on their way to Notre Dame Stadium on Saturday, September 20, 2025 where they will meet the Notre Dame Fighting Irish (0-1). Notre Dame opens this game as 27.0-point favorites from oddsmakers. The total is 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

NIU Huskies vs Mississippi State Bulldogs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Mississippi State Bulldogs (3-0) will play the NIU Huskies (1-1) at Davis Wade Stadium on Saturday, September 20, 2025. Mississippi State is 21.5-point favorites. The over/under is 50. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

South Carolina Gamecocks vs Missouri Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

Memorial Stadium is the site where the Missouri Tigers (3-0) will try to defeat the South Carolina Gamecocks (2-1) on Saturday, September 20, 2025. South Carolina opens as 13.5-point underdogs. The over/under comes in at 46.5. This report has odds and your NCAA football predictions for todays game against the spread.

James Madison Dukes vs Liberty Flames Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Liberty Flames (1-2) will compete against the James Madison Dukes (1-1) at Williams Stadium on Saturday, September 20, 2025. Liberty opens this contest as 10.0-point dogs. The total has been set at 49. This report includes betting odds and our expert football picks for todays game.

Arizona State Sun Devils vs Baylor Bears Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Baylor Bears (2-1) are welcoming the Arizona State Sun Devils (1-1) at McLane Stadium on Saturday, September 20, 2025. Baylor opens as 2.0-point favorites. The total has been set at 60. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Tulane Green Wave vs Ole Miss Rebels Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Tulane Green Wave (2-0) are hitting the road to Vaught-Hemingway Stadium on Saturday, September 20, 2025 where they will attempt to beat the Ole Miss Rebels (3-0). Ole Miss opens as 12.0-point favorites. The over/under is set at 61.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

North Carolina Tar Heels vs UCF Knights Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The North Carolina Tar Heels (2-1) are hitting the road to FBC Mortgage Stadium on Saturday, September 20, 2025 where they will meet the UCF Knights (2-0). UCF opens this matchup as 6.5-point favorites from oddsmakers. The betting total is set at 49. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Auburn Tigers vs Oklahoma Sooners Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Memorial Stadium is the location where the Oklahoma Sooners (3-0) will try to defeat the Auburn Tigers (3-0) on Saturday, September 20, 2025. Oklahoma opens this contest as 7.0-point favorites from Vegas oddsmakers. The total is 48.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

UTSA Roadrunners vs Colorado State Rams Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Colorado State Rams (1-1) will try to beat the UTSA Roadrunners (1-2) at Canvas Stadium on Saturday, September 20, 2025. Colorado State opens this contest as 4.5-point dogs. The over/under is set at 59.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Ohio Bobcats vs Ohio State Buckeyes Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Ohio Stadium is the location where the Ohio State Buckeyes (2-0) will attempt to beat the Ohio Bobcats (1-1) on Saturday, September 13, 2025. Ohio State opens this contest as 32.0-point favorites. The over/under is set at 53. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Arkansas Razorbacks vs Ole Miss Rebels Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Arkansas Razorbacks (2-0) are en route to Vaught-Hemingway Stadium on Saturday, September 13, 2025 where they will play the Ole Miss Rebels (2-0). Arkansas opens as 9.5-point underdogs. The total is 63. This games report has current odds, betting predictions, and free picks against the spread.

Washington State Cougars vs North Texas Mean Green Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

DATCU Stadium is where the North Texas Mean Green (2-0) will try to beat the Washington State Cougars (1-0) on Saturday, September 13, 2025. North Texas opens this matchup as 4.5-point favorites from oddsmakers. The total is set at 58.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

East Carolina Pirates vs Coastal Carolina Chanticleers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Brooks Stadium is the location where the Coastal Carolina Chanticleers (1-1) will meet the East Carolina Pirates (1-1) on Saturday, September 13, 2025. East Carolina opens as 7.0-point favorites from Vegas oddsmakers. The betting total is set at 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

UTEP Miners vs Texas Longhorns Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Texas Longhorns (1-1) will compete against the UTEP Miners (0-1) at DKR-Texas Memorial Stadium on Saturday, September 13, 2025. Texas opens as 41.5-point favorites. The over/under has been set at 51.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Louisiana Ragin' Cajuns vs Missouri Tigers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Louisiana Ragin' Cajuns (1-1) are headed to Memorial Stadium on Saturday, September 13, 2025 where they will play the Missouri Tigers (2-0). Missouri opens this game as 27.5-point favorites. The over/under comes in at 49.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Oregon Ducks vs Northwestern Wildcats Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Martin Stadium is where the Northwestern Wildcats (1-1) will go up against the Oregon Ducks (2-0) on Saturday, September 13, 2025. Northwestern opens this contest as 27.5-point dogs. The total is set at 51. This report has odds and your NCAA football predictions for todays game against the spread.

Georgia Bulldogs vs Tennessee Volunteers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

Neyland Stadium is where the Tennessee Volunteers (2-0) will try to beat the Georgia Bulldogs (2-0) on Saturday, September 13, 2025. Georgia opens as 4.5-point favorites. The total is 50.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Minnesota Golden Gophers vs California Golden Bears Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Minnesota Golden Gophers (2-0) are en route to California Memorial Stadium on Saturday, September 13, 2025 where they will compete against the California Golden Bears (2-0). Minnesota is 2.5-point favorites. The total is 44. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Buffalo Bulls vs Kent State Golden Flashes Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Kent State Golden Flashes (1-1) will go up against the Buffalo Bulls (1-1) at Dix Stadium on Saturday, September 13, 2025. Buffalo opens this contest as 21.5-point favorites from Vegas oddsmakers. The betting total comes in at 48.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

NC State Wolfpack vs Wake Forest Demon Deacons Prediction, 9/11/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The NC State Wolfpack (2-0) are on their way to Allegacy Federal Credit Union Stadium on Thursday, September 11, 2025 where they will meet the Wake Forest Demon Deacons (2-0). NC State opens this contest as 7.0-point favorites from oddsmakers. The total is set at 53.5. This matchup report includes college football odds, predictions, and a free pick against the spread.

South Alabama Jaguars vs Auburn Tigers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Auburn Tigers (2-0) are hosting the South Alabama Jaguars (1-1) at Jordan-Hare Stadium on Saturday, September 13, 2025. Auburn opens this game as 24.5-point favorites from Vegas oddsmakers. The total is set at 53.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Iowa State Cyclones vs Arkansas State Red Wolves Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Arkansas State Red Wolves (1-1) will play the Iowa State Cyclones (3-0) at Centennial Bank Stadium on Saturday, September 13, 2025. Iowa State is 20.5-point favorites. The total is 55.5. This report has odds and your NCAA football predictions for todays game against the spread.

New Mexico Lobos vs UCLA Bruins Prediction, 9/12/2025 College Football Picks, Best Bets & Odds
by Parlays Pundit - 9/8/2025

Rose Bowl is where the UCLA Bruins (0-2) will try to defeat the New Mexico Lobos (1-1) on Friday, September 12, 2025. New Mexico opens this game as 16.5-point dogs from oddsmakers. The betting total is set at 54. We have included an expert college football pick and parlay for todays game against the spread.

USF Bulls vs Miami Hurricanes Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

USF Bulls Miami Hurricanes 9/13/2025 4:30 PM 0 Hard Rock Stadium Miami Gardens, FLThe USF Bulls (2-0) are headed to Hard Rock Stadium on Saturday, September 13, 2025 where they will go up against the Miami Hurricanes (2-0). Miami opens this contest as 17.0-point favorites from oddsmakers. The total comes in at 55. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

New Mexico State Aggies vs Louisiana Tech Bulldogs Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The New Mexico State Aggies (2-0) are on their way to Joe Aillet Stadium on Saturday, September 13, 2025 where they will take on the Louisiana Tech Bulldogs (1-1). Louisiana Tech is 9.5-point favorites from oddsmakers. The over/under has been set at 43. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Akron Zips vs UAB Blazers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The UAB Blazers (1-1) are welcoming the Akron Zips (0-2) at Protective Stadium on Saturday, September 13, 2025. Akron opens as 11.5-point underdogs. The total comes in at 53.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Boston College Eagles vs Stanford Cardinal Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Boston College Eagles (1-1) are headed to Stanford Stadium on Saturday, September 13, 2025 where they will play the Stanford Cardinal (0-1). Boston College is 10.5-point favorites. The betting total is set at 45. This matchup report has your NCAA football pick of the day as well as college football odds for the game.