Free College Football Picks: Today's Expert Picks Against the Spread, College Football Best Bets, Predictions and Parlays.

UCLA Bruins vs Oregon Ducks Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The UCLA Bruins (6-0) are headed to Autzen Stadium on Saturday where they will take on the Oregon Ducks (5-1). UCLA opens this matchup as 4.5-point underdogs from oddsmakers. The total has been set at 72. This report includes betting odds and our expert football picks for todays game.

West Virginia Mountaineers vs Texas Tech Red Raiders Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Texas Tech Red Raiders (3-3) are hosting the West Virginia Mountaineers (3-3) at Jones AT&T Stadium on Saturday. Texas Tech opens this matchup as 4-point favorites. The total is 70.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Kansas Jayhawks vs Baylor Bears Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Kansas Jayhawks (5-2) are hitting the road to McLane Stadium on Saturday where they will take on the Baylor Bears (3-3). Baylor opens this game as 9-point favorites. The total comes in at 62.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Boston College Eagles vs Wake Forest Demon Deacons Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

Truist Field is the location where the Wake Forest Demon Deacons (5-1) will go up against the Boston College Eagles (2-4) on Saturday. Wake Forest is 20.5-point favorites from oddsmakers. The over/under is set at 61.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

San Jose State Spartans vs New Mexico State Aggies Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

Aggie Memorial Stadium is where the New Mexico State Aggies (2-5) will take on the San Jose State Spartans (4-2) on Saturday. San Jose State opens this contest as 22-point favorites from Vegas oddsmakers. The total has been set at 44. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Fresno State Bulldogs vs New Mexico Lobos Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The New Mexico Lobos (2-5) will go up against the Fresno State Bulldogs (2-4) at University Stadium on Saturday. Fresno State opens this contest as 13-point favorites from oddsmakers. The total comes in at 43. This report includes betting odds and our expert football picks for todays game.

Vanderbilt Commodores vs Missouri Tigers Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Missouri Tigers (2-4) welcome the Vanderbilt Commodores (3-4) at Memorial Stadium/Faurot Field on Saturday. Missouri opens as 14.5-point favorites from Vegas oddsmakers. The over/under comes in at 56.5. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Bowling Green Falcons vs Central Michigan Chippewas Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Central Michigan Chippewas (2-5) are welcoming the Bowling Green Falcons (3-4) at Kelly/Shorts Stadium on Saturday. Bowling Green opens this game as 7-point dogs from Vegas oddsmakers. The betting total is set at 50.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

NIU Huskies vs Ohio Bobcats Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Ohio Bobcats (4-3) host the NIU Huskies (2-5) at Peden Stadium on Saturday. NIU opens this game as 1-point favorites. The total has been set at 66. This games report has current odds, betting predictions, and free picks against the spread.

Georgia Southern Eagles vs Old Dominion Monarchs Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Georgia Southern Eagles (4-3) are hitting the road to S.B. Ballard Stadium on Saturday where they will try to beat the Old Dominion Monarchs (3-3). Georgia Southern is 2.5-point dogs from oddsmakers. The over/under is 67.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Arizona State Sun Devils vs Stanford Cardinal Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Stanford Cardinal (2-3) will try to beat the Arizona State Sun Devils (2-4) at Stanford Stadium on Saturday. Stanford opens as 3-point favorites. The betting total is set at 54.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Iowa Hawkeyes vs Ohio State Buckeyes Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

Ohio Stadium is the site where the Ohio State Buckeyes (6-0) will try to defeat the Iowa Hawkeyes (3-3) on Saturday. Ohio State opens as 28-point favorites from oddsmakers. The over/under is set at 49. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Florida Atlantic Owls vs UTEP Miners Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

Sun Bowl is where the UTEP Miners (3-4) will play the Florida Atlantic Owls (3-4) on Saturday. UTEP is 5-point underdogs. The betting total comes in at 51. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

BYU Cougars vs Liberty Flames Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

Williams Stadium is where the Liberty Flames (6-1) will play the BYU Cougars (4-3) on Saturday. BYU opens this contest as 5-point favorites from oddsmakers. The total has been set at 58. This games report has current odds, betting predictions, and free picks against the spread.

Purdue Boilermakers vs Wisconsin Badgers Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Wisconsin Badgers (3-4) will take on the Purdue Boilermakers (5-2) at Camp Randall Stadium on Saturday. Purdue opens this matchup as 1-point dogs from Vegas oddsmakers. The total comes in at 53. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Texas A&M Aggies vs South Carolina Gamecocks Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Texas A&M Aggies (3-3) are hitting the road to Williams-Brice Stadium on Saturday where they will meet the South Carolina Gamecocks (4-2). South Carolina opens this contest as 4.5-point dogs. The total comes in at 45.5. This report has odds and your NCAA football predictions for todays game against the spread.

Ole Miss Rebels vs LSU Tigers Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The LSU Tigers (5-2) are hosting the Ole Miss Rebels (7-0) at Tiger Stadium on Saturday. LSU is 2.5-point dogs. The total is set at 63. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Boise State Broncos vs Air Force Falcons Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

Falcon Stadium is the site where the Air Force Falcons (5-2) will take on the Boise State Broncos (4-2) on Saturday. Boise State opens this contest as 4-point underdogs from Vegas oddsmakers. The over/under is 48. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Northwestern Wildcats vs Maryland Terrapins Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Maryland Terrapins (5-2) will play the Northwestern Wildcats (1-5) at Maryland Stadium on Saturday. Northwestern opens this contest as 12-point underdogs. The betting total comes in at 52. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

North Texas Mean Green vs UTSA Roadrunners Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The UTSA Roadrunners (5-2) will compete against the North Texas Mean Green (4-3) at Alamodome on Saturday. UTSA opens this game as 9-point favorites from Vegas oddsmakers. The over/under is set at 69. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Rice Owls vs Louisiana Tech Bulldogs Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

Joe Aillet Stadium is the site where the Louisiana Tech Bulldogs (2-4) will go up against the Rice Owls (3-3) on Saturday. Louisiana Tech is 1-point underdogs. The over/under has been set at 61.5. This games report has current odds, betting predictions, and free picks against the spread.

Kansas State Wildcats vs TCU Horned Frogs Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The TCU Horned Frogs (6-0) will go up against the Kansas State Wildcats (5-1) at Amon G. Carter Stadium on Saturday. Kansas State opens as 5-point dogs. The over/under has been set at 58.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Washington Huskies vs California Golden Bears Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The California Golden Bears (3-3) welcome the Washington Huskies (5-2) at California Memorial Stadium on Saturday. California opens as 9-point dogs from oddsmakers. The total is set at 55. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Syracuse Orange vs Clemson Tigers Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Syracuse Orange (6-0) are en route to Memorial Stadium on Saturday where they will go up against the Clemson Tigers (7-0). Syracuse opens as 14-point underdogs from oddsmakers. The total is 51.5. This report has odds and your NCAA football predictions for todays game against the spread.

Houston Cougars vs Navy Midshipmen Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Navy Midshipmen (2-4) welcome the Houston Cougars (3-3) at Navy-Marine Corps Memorial Stadium on Saturday. Houston is 3-point favorites. The over/under has been set at 53.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Utah State Aggies vs Wyoming Cowboys Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Wyoming Cowboys (4-3) will compete against the Utah State Aggies (3-4) at Jonah Field at War Memorial Stadium on Saturday. Utah State opens this matchup as 3.5-point underdogs. The total has been set at 42.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

FIU Panthers vs Charlotte 49ers Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

Jerry Richardson Stadium is where the Charlotte 49ers (1-6) will compete against the FIU Panthers (2-4) on Saturday. Charlotte opens as 14-point favorites from Vegas oddsmakers. The over/under has been set at 60. This report has odds and your NCAA football predictions for todays game against the spread.

UNLV Runnin' Rebels vs Notre Dame Fighting Irish Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

Notre Dame Stadium is the site where the Notre Dame Fighting Irish (3-3) will attempt to defeat the UNLV Runnin' Rebels (4-3) on Saturday. UNLV opens this contest as 24.5-point underdogs. The betting total is set at 50. This matchup report includes Vegas odds and a free college football prediction for tonight.

Duke Blue Devils vs Miami Hurricanes Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Duke Blue Devils (4-3) are hitting the road to Hard Rock Stadium on Saturday where they will attempt to defeat the Miami Hurricanes (3-3). Miami opens this game as 8.5-point favorites. The total is 60.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Akron Zips vs Kent State Golden Flashes Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Kent State Golden Flashes (2-5) will play the Akron Zips (1-6) at Dix Stadium on Saturday. Kent State opens as 20-point favorites. The over/under is 67. This report has odds and your NCAA football predictions for todays game against the spread.

UCF Knights vs East Carolina Pirates Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The UCF Knights (5-1) are en route to Dowdy-Ficklen Stadium on Saturday where they will compete against the East Carolina Pirates (4-3). UCF opens this matchup as 4.5-point favorites. The total is set at 63. This matchup report includes Vegas odds and a free college football prediction for tonight.

Southern Miss Golden Eagles vs Texas State Bobcats Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Southern Miss Golden Eagles (3-3) are hitting the road to Bobcat Stadium on Saturday where they will take on the Texas State Bobcats (3-4). Texas State is 1-point underdogs from Vegas oddsmakers. The over/under comes in at 45. This report includes betting odds and our expert football picks for todays game.

Arkansas State Red Wolves vs Louisiana Ragin' Cajuns Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Arkansas State Red Wolves (2-5) are en route to Cajun Field on Saturday where they will go up against the Louisiana Ragin' Cajuns (3-3). Arkansas State is 7-point underdogs from oddsmakers. The total is set at 51.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Mississippi State Bulldogs vs Alabama Crimson Tide Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Alabama Crimson Tide (6-1) will try to beat the Mississippi State Bulldogs (5-2) at Bryant-Denny Stadium on Saturday. Alabama opens this game as 21.5-point favorites. The total is 62. This games report has current odds, betting predictions, and free picks against the spread.

Eastern Michigan Eagles vs Ball State Cardinals Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Eastern Michigan Eagles (4-3) are headed to Scheumann Stadium on Saturday where they will try to beat the Ball State Cardinals (4-3). Ball State is 3-point favorites. The total is set at 0.57. This matchup report includes odds, betting predictions and a free pick against the spread.

Memphis Tigers vs Tulane Green Wave Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Tulane Green Wave (6-1) are welcoming the Memphis Tigers (4-3) at Yulman Stadium on Saturday. Tulane opens this matchup as 6-point favorites from oddsmakers. The betting total is set at 55. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Indiana Hoosiers vs Rutgers Scarlet Knights Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Indiana Hoosiers (3-4) are hitting the road to SHI Stadium on Saturday where they will take on the Rutgers Scarlet Knights (3-3). Indiana opens as 1.5-point dogs. The over/under is 45. This matchup report includes betting lines and our NCAA football pick of the day for this game.

UL Monroe Warhawks vs Army Black Knights Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The Army Black Knights (2-4) will try to defeat the UL Monroe Warhawks (2-5) at Michie Stadium on Saturday. Army opens this contest as 7.5-point favorites from Vegas oddsmakers. The total is set at 56.5. This report includes betting odds and our expert football picks for todays game.

Hawaii Warriors vs Colorado State Rams Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

Canvas Stadium is where the Colorado State Rams (1-5) will meet the Hawaii Warriors (2-5) on Saturday. Hawaii opens this matchup as 4-point underdogs. The over/under is set at 47. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Tulsa Golden Hurricane vs Temple Owls Prediction, 10/21/2022 College Football Picks, Best Bets & Odds
by Parlays Pundit - 10/17/2022

The Temple Owls (2-4) welcome the Tulsa Golden Hurricane (2-4) at Lincoln Financial Field on Friday. Tulsa opens this matchup as 12-point favorites. The over/under has been set at 52.5. We have included an expert college football pick and parlay for todays game against the spread.

Pittsburgh Panthers vs Louisville Cardinals Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

Cardinal Stadium is the location where the Louisville Cardinals (3-3) will compete against the Pittsburgh Panthers (4-2) on Saturday. Louisville opens this matchup as 1-point favorites. The total comes in at 56.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

San Diego State Aztecs vs Nevada Wolf Pack Prediction, 10/22/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/17/2022

The San Diego State Aztecs (3-3) are hitting the road to Mackay Stadium on Saturday where they will attempt to defeat the Nevada Wolf Pack (2-5). San Diego State opens this contest as 9-point favorites. The total has been set at 37.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Troy Trojans vs South Alabama Jaguars Prediction, 10/20/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 10/17/2022

The Troy Trojans (5-2) are on their way to Hancock Whitney Stadium on Thursday where they will meet the South Alabama Jaguars (5-1). Troy opens this matchup as 4-point dogs. The total has been set at 48. This matchup report includes football betting lines and our pick of the day for this game.

Virginia Cavaliers vs Georgia Tech Yellow Jackets Prediction, 10/20/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 10/17/2022

The Virginia Cavaliers (2-4) are on their way to Bobby Dodd Stadium on Thursday where they will take on the Georgia Tech Yellow Jackets (3-3). Georgia Tech opens this game as 4-point favorites from oddsmakers. The total is set at 45.5. This report includes betting predictions and our expert college football picks for todays game.

Penn State Nittany Lions vs Michigan Wolverines Prediction, 10/15/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 10/10/2022

The Penn State Nittany Lions (5-0) are en route to Michigan Stadium on Saturday where they will meet the Michigan Wolverines (6-0). Penn State is 7-point underdogs from Vegas oddsmakers. The betting total comes in at 50. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.