Free College Football Picks: Today's Expert Picks Against the Spread, College Football Best Bets, Predictions and Parlays.

California Golden Bears vs Notre Dame Fighting Irish Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

Notre Dame Stadium is where the Notre Dame Fighting Irish (0-2) will take on the California Golden Bears (2-0) on Saturday. Notre Dame opens this contest as 12.5-point favorites. The betting total comes in at 43. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Charlotte 49ers vs Georgia State Panthers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Georgia State Panthers (0-2) are hosting the Charlotte 49ers (0-3) at Center Parc Stadium on Saturday. Georgia State opens this matchup as 20-point favorites from oddsmakers. The total is 60.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Florida State Seminoles vs Louisville Cardinals Prediction, 9/16/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Louisville Cardinals (1-1) welcome the Florida State Seminoles (2-0) at Cardinal Stadium on Friday. Florida State is 1-point underdogs. The total has been set at 54. This matchup report includes college football odds, predictions, and a free pick against the spread.

SMU Mustangs vs Maryland Terrapins Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

Maryland Stadium is where the Maryland Terrapins (2-0) will meet the SMU Mustangs (2-0) on Saturday. SMU opens as 2-point underdogs from Vegas oddsmakers. The total is set at 69. This matchup report includes odds, betting predictions and a free pick against the spread.

Texas Tech Red Raiders vs NC State Wolfpack Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Texas Tech Red Raiders (2-0) are traveling to Carter-Finley Stadium on Saturday where they will play the NC State Wolfpack (2-0). NC State opens as 8-point favorites. The total is set at 56. This report has odds and your NCAA football predictions for todays game against the spread.

Ole Miss Rebels vs Georgia Tech Yellow Jackets Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Ole Miss Rebels (2-0) are headed to Bobby Dodd Stadium on Saturday where they will attempt to defeat the Georgia Tech Yellow Jackets (1-1). Georgia Tech opens this contest as 16-point underdogs. The total is set at 60.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Vanderbilt Commodores vs NIU Huskies Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Huskie Stadium is the site where the NIU Huskies (1-1) will meet the Vanderbilt Commodores (2-1) on Saturday. Vanderbilt opens as 2.5-point favorites from oddsmakers. The betting total comes in at 62. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Pittsburgh Panthers vs Western Michigan Broncos Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Western Michigan Broncos (1-1) will go up against the Pittsburgh Panthers (1-1) at Waldo Stadium on Saturday. Pittsburgh opens this game as 10-point favorites. The betting total comes in at 54.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

UL Monroe Warhawks vs Alabama Crimson Tide Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The UL Monroe Warhawks (1-1) are headed to Bryant-Denny Stadium on Saturday where they will take on the Alabama Crimson Tide (2-0). Alabama is 51-point favorites. The betting total comes in at 60.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Oklahoma Sooners vs Nebraska Cornhuskers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Parlays Pundit - 9/12/2022

The Nebraska Cornhuskers (1-2) will compete against the Oklahoma Sooners (2-0) at Memorial Stadium on Saturday. Oklahoma opens this game as 17-point favorites. The betting total comes in at 64. We have included an expert college football pick and parlay for todays game against the spread.

Penn State Nittany Lions vs Auburn Tigers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Penn State Nittany Lions (2-0) are traveling to Jordan-Hare Stadium on Saturday where they will attempt to beat the Auburn Tigers (2-0). Auburn opens this matchup as 2.5-point dogs. The total has been set at 48.5. This games report has current odds, betting predictions, and free picks against the spread.

Buffalo Bulls vs Coastal Carolina Chanticleers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

Brooks Stadium is the location where the Coastal Carolina Chanticleers (2-0) will try to defeat the Buffalo Bulls (0-2) on Saturday. Buffalo opens this game as 20-point underdogs. The betting total is set at 59. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Rutgers Scarlet Knights vs Temple Owls Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Temple Owls (1-1) will compete against the Rutgers Scarlet Knights (2-0) at Lincoln Financial Field on Saturday. Rutgers is 16-point favorites from Vegas oddsmakers. The betting total comes in at 44.5. This report includes betting odds and our expert football picks for todays game.

Georgia Bulldogs vs South Carolina Gamecocks Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Georgia Bulldogs (2-0) are headed to Williams-Brice Stadium on Saturday where they will try to defeat the South Carolina Gamecocks (1-1). Georgia is 27-point favorites. The total comes in at 51.5. This matchup report includes football betting lines and our pick of the day for this game.

Texas State Bobcats vs Baylor Bears Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Baylor Bears (1-1) will take on the Texas State Bobcats (1-1) at McLane Stadium on Saturday. Texas State is 33.5-point dogs from oddsmakers. The total is 52.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Cincinnati Bearcats vs Miami RedHawks Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Paul Brown Stadium is where the Miami RedHawks (1-1) will try to beat the Cincinnati Bearcats (1-1) on Saturday. Cincinnati opens this contest as 20-point favorites from oddsmakers. The over/under has been set at 52. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Connecticut Huskies vs Michigan Wolverines Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

Michigan Stadium is the site where the Michigan Wolverines (2-0) will try to defeat the Connecticut Huskies (1-2) on Saturday. Connecticut opens this game as 45.5-point underdogs from oddsmakers. The betting total comes in at 59.5. This games report has current odds, betting predictions, and free picks against the spread.

Western Kentucky Hilltoppers vs Indiana Hoosiers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Indiana Hoosiers (2-0) welcome the Western Kentucky Hilltoppers (2-0) at Memorial Stadium on Saturday. Indiana opens this contest as 9.5-point favorites from Vegas oddsmakers. The betting total comes in at 59. This report has odds and your NCAA football predictions for todays game against the spread.

South Alabama Jaguars vs UCLA Bruins Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The UCLA Bruins (2-0) will compete against the South Alabama Jaguars (2-0) at Rose Bowl on Saturday. UCLA is 11-point favorites. The over/under has been set at 59. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Tulane Green Wave vs Kansas State Wildcats Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Kansas State Wildcats (2-0) host the Tulane Green Wave (2-0) at Bill Snyder Family Stadium on Saturday. Kansas State opens as 20-point favorites from oddsmakers. The over/under comes in at 48.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Marshall Thundering Herd vs Bowling Green Falcons Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

Doyt L. Perry Stadium is where the Bowling Green Falcons (0-2) will meet the Marshall Thundering Herd (2-0) on Saturday. Marshall opens this contest as 18-point favorites from oddsmakers. The total is set at 54. This games report has current odds, betting predictions, and free picks against the spread.

USF Bulls vs Florida Gators Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The USF Bulls (1-1) are en route to Ben Hill Griffin Stadium on Saturday where they will play the Florida Gators (1-1). USF is 26-point dogs. The over/under is 59. This report includes betting odds and our expert football picks for todays game.

UCF Knights vs Florida Atlantic Owls Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The UCF Knights (1-1) are traveling to FAU Stadium on Saturday where they will try to defeat the Florida Atlantic Owls (2-1). UCF is 12-point favorites from Vegas oddsmakers. The over/under is 58. This games report has current odds, betting predictions, and free picks against the spread.

Akron Zips vs Tennessee Volunteers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Neyland Stadium is the location where the Tennessee Volunteers (2-0) will take on the Akron Zips (1-1) on Saturday. Tennessee opens this contest as 48-point favorites. The over/under comes in at 66. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

San Diego State Aztecs vs Utah Utes Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Utah Utes (1-1) will go up against the San Diego State Aztecs (1-1) at Rice-Eccles Stadium on Saturday. San Diego State opens this matchup as 23-point dogs from Vegas oddsmakers. The over/under comes in at 49.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Toledo Rockets vs Ohio State Buckeyes Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Toledo Rockets (2-0) are headed to Ohio Stadium on Saturday where they will attempt to defeat the Ohio State Buckeyes (2-0). Ohio State is 31.5-point favorites. The over/under has been set at 61. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Fresno State Bulldogs vs USC Trojans Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

Los Angeles Memorial Coliseum is where the USC Trojans (2-0) will play the Fresno State Bulldogs (1-1) on Saturday. Fresno State is 14-point underdogs. The over/under has been set at 68.5. This report includes betting odds and our expert football picks for todays game.

Miami Hurricanes vs Texas A&M Aggies Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Kyle Field is the location where the Texas A&M Aggies (1-1) will try to defeat the Miami Hurricanes (2-0) on Saturday. Miami opens this game as 6.5-point dogs from Vegas oddsmakers. The over/under has been set at 49. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Purdue Boilermakers vs Syracuse Orange Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

JMA Wireless Dome is the site where the Syracuse Orange (2-0) will meet the Purdue Boilermakers (1-1) on Saturday. Syracuse opens this matchup as 1-point underdogs. The total comes in at 57.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Michigan State Spartans vs Washington Huskies Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Husky Stadium is the location where the Washington Huskies (2-0) will play the Michigan State Spartans (2-0) on Saturday. Washington opens this matchup as 3-point favorites. The over/under is 54. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Louisiana Tech Bulldogs vs Clemson Tigers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Clemson Tigers (2-0) will play the Louisiana Tech Bulldogs (1-1) at Memorial Stadium on Saturday. Louisiana Tech opens this matchup as 31-point underdogs from oddsmakers. The betting total is set at 55.5. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Georgia Southern Eagles vs UAB Blazers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The UAB Blazers (1-1) will take on the Georgia Southern Eagles (2-0) at Protective Stadium on Saturday. Georgia Southern opens this matchup as 11-point dogs from oddsmakers. The betting total is set at 56.5. This report includes betting odds and our expert football picks for todays game.

Kansas Jayhawks vs Houston Cougars Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

TDECU Stadium is where the Houston Cougars (1-1) will attempt to defeat the Kansas Jayhawks (2-0) on Saturday. Houston opens this matchup as 8-point favorites. The over/under comes in at 63. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Arkansas State Red Wolves vs Memphis Tigers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Memphis Tigers (1-1) are hosting the Arkansas State Red Wolves (1-1) at Liberty Bowl Memorial Stadium on Saturday. Arkansas State opens this matchup as 13-point dogs from Vegas oddsmakers. The over/under is set at 62. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Mississippi State Bulldogs vs LSU Tigers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The LSU Tigers (1-1) welcome the Mississippi State Bulldogs (2-0) at Tiger Stadium on Saturday. LSU opens this game as 1-point dogs. The over/under is set at 54. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

North Texas Mean Green vs UNLV Runnin' Rebels Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The North Texas Mean Green (2-1) are on their way to Allegiant Stadium on Saturday where they will go up against the UNLV Runnin' Rebels (1-1). North Texas opens this game as 1-point dogs from Vegas oddsmakers. The total comes in at 57. This matchup report includes Vegas odds and a free college football prediction for tonight.

UTSA Roadrunners vs Texas Longhorns Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The UTSA Roadrunners (1-1) are on their way to DKR-Texas Memorial Stadium on Saturday where they will try to beat the Texas Longhorns (1-1). UTSA opens this game as 13-point dogs from Vegas oddsmakers. The total has been set at 61.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Liberty Flames vs Wake Forest Demon Deacons Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Truist Field is where the Wake Forest Demon Deacons (2-0) will compete against the Liberty Flames (2-0) on Saturday. Liberty is 16-point underdogs. The total is 63.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

New Mexico State Aggies vs Wisconsin Badgers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Wisconsin Badgers (1-1) are hosting the New Mexico State Aggies (0-3) at Camp Randall Stadium on Saturday. Wisconsin opens as 37.5-point favorites. The total is 48. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Air Force Falcons vs Wyoming Cowboys Prediction, 9/16/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

The Wyoming Cowboys (2-1) host the Air Force Falcons (2-0) at Jonah Field at War Memorial Stadium on Friday. Air Force is 16-point favorites. The total has been set at 50. This report includes betting predictions and our expert college football picks for todays game.

Colorado State Rams vs Washington State Cougars Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Tony Sink - 9/12/2022

The Washington State Cougars (2-0) are hosting the Colorado State Rams (0-2) at Martin Stadium on Saturday. Washington State opens this matchup as 17-point favorites. The over/under is set at 53.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Old Dominion Monarchs vs Virginia Cavaliers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/12/2022

Scott Stadium is where the Virginia Cavaliers (1-1) will attempt to beat the Old Dominion Monarchs (1-1) on Saturday. Old Dominion opens this contest as 10-point underdogs. The total is set at 53. This matchup report includes betting lines and our NCAA football pick of the day for this game.

UTEP Miners vs New Mexico Lobos Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The New Mexico Lobos (1-1) will go up against the UTEP Miners (1-2) at University Stadium on Saturday. UTEP opens as 5.5-point favorites. The over/under comes in at 41.5. This report has odds and your NCAA football predictions for todays game against the spread.

Troy Trojans vs Appalachian State Mountaineers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Appalachian State Mountaineers (1-1) will compete against the Troy Trojans (1-1) at Kidd Brewer Stadium on Saturday. Troy opens this game as 13-point underdogs. The over/under is 54. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Colorado Buffaloes vs Minnesota Golden Gophers Prediction, 9/17/2022 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/12/2022

The Minnesota Golden Gophers (2-0) welcome the Colorado Buffaloes (0-2) at Huntington Bank Stadium on Saturday. Minnesota is 28.5-point favorites. The over/under is set at 46.5. This report has odds and your NCAA football predictions for todays game against the spread.