MLB Picks: Parlays, Expert Predictions, Best Bets and Player Props.

Houston Astros vs Baltimore Orioles Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 8/21/2025

The Houston Astros are set to play the Baltimore Orioles at Oriole Park at Camden Yards on Friday, August 22, 2025. That contest transpires at 7:05 PM EST at Oriole Park at Camden Yards in Baltimore, MD. We have included an expert pick and prediction for todays game against the spread.

St. Louis Cardinals vs Tampa Bay Rays Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 8/21/2025

The St. Louis Cardinals are scheduled to meet the Tampa Bay Rays at George M. Steinbrenner Field on Friday, August 22, 2025. That game is set to take place at 7:35 PM EST at George M. Steinbrenner Field in Tampa, FL. This report has odds and your MLB predictions for todays game against the spread.

Toronto Blue Jays vs Miami Marlins Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 8/21/2025

The Toronto Blue Jays are set to play the Miami Marlins at loanDepot park on Friday, August 22, 2025. That game is set to begin at 7:10 PM EST at loanDepot park in Miami, FL. This matchup report includes betting lines and our pick of the day for this game.

Boston Red Sox vs New York Yankees Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 8/21/2025

The Boston Red Sox are on the docket to play the New York Yankees at Yankee Stadium on Friday, August 22, 2025. That game occurs at 7:05 PM EST at Yankee Stadium in Bronx, NY. This matchup report includes odds, betting trends and a free pick against the spread.

Los Angeles Dodgers vs San Diego Padres Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 8/21/2025

The Los Angeles Dodgers are scheduled to meet the San Diego Padres at Petco Park on Friday, August 22, 2025. That contest can be observed at 9:40 PM EST at Petco Park in San Diego, CA. This Matchup report includes Vegas odds and a free baseball pick for tonight.

Minnesota Twins vs Chicago White Sox Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 8/21/2025

The Minnesota Twins are on the docket to play the Chicago White Sox at Rate Field on Friday, August 22, 2025. That matchup can be seen at 7:40 PM EST at Rate Field in Chicago, IL. We have included an expert pick for todays game against the spread.

Sacramento Athletics vs Seattle Mariners Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 8/21/2025

The Sacramento Athletics are set to play the Seattle Mariners at T-Mobile Park on Friday, August 22, 2025. That matchup is set to start at 10:10 PM EST at T-Mobile Park in Seattle, WA. This report includes betting odds and our expert MLB picks for todays game.

New York Mets vs Atlanta Braves Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 8/21/2025

The New York Mets are scheduled to meet the Atlanta Braves at Truist Park on Friday, August 22, 2025. That matchup is set to start at 7:15 PM EST at Truist Park in Cumberland, GA. This matchup report includes betting lines and our pick of the day for this game.

San Francisco Giants vs Milwaukee Brewers Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 8/21/2025

The San Francisco Giants are set to take on the Milwaukee Brewers at American Family Field on Friday, August 22, 2025. That matchup is scheduled to be shown at 8:10 PM EST at American Family Field in Milwaukee, WI. We have included an expert pick and parlay for todays game against the spread.

Cincinnati Reds vs Arizona Diamondbacks Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Parlay's Pundit - 8/21/2025

The Cincinnati Reds are on the docket to play the Arizona Diamondbacks at Chase Field on Friday, August 22, 2025. That encounter can be caught at 9:40 PM EST at Chase Field in Phoenix, AZ. This matchup report includes odds, betting trends and a free pick against the spread.

Cleveland Guardians vs Texas Rangers Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 8/21/2025

The Cleveland Guardians are on the docket to take on the Texas Rangers at Globe Life Field on Friday, August 22, 2025. That game is scheduled to be shown at 8:05 PM EST at Globe Life Field in Arlington, TX. This Matchup report has your MLB pick of the day as well as MLB odds for the game.

Kansas City Royals vs Detroit Tigers Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 8/21/2025

The Kansas City Royals are scheduled to take on the Detroit Tigers at Comerica Park on Friday, August 22, 2025. That encounter occurs at 7:10 PM EST at Comerica Park in Detroit, MI. This game report has an MLB pick, betting odds, and trends for tonights key matchup.

Washington Nationals vs Philadelphia Phillies Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 8/21/2025

The Washington Nationals are scheduled to take on the Philadelphia Phillies at Citizens Bank Park on Friday, August 22, 2025. That game is set to begin at 6:45 PM EST at Citizens Bank Park in Philadelphia, PA. This games report has current odds, betting trends, and free picks against the spread.

Colorado Rockies vs Pittsburgh Pirates Prediction, 8/22/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 8/21/2025

The Colorado Rockies are set to meet the Pittsburgh Pirates at PNC Park on Friday, August 22, 2025. That baseball game can be streamed at 6:40 PM EST at PNC Park in Pittsburgh, PA. This matchup report has Vegas lines and an expert MLB pick for your daily winner.