Free College Football Picks: Today's Expert Picks Against the Spread, College Football Best Bets, Predictions and Parlays.

Bowling Green Falcons vs Louisville Cardinals Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

L&N Federal Credit Union Stadium is the location where the Louisville Cardinals (2-0) will attempt to beat the Bowling Green Falcons (2-1) on Saturday, September 20, 2025. Louisville opens as 26.5-point favorites. The betting total is set at 51.5. This report has odds and your NCAA football predictions for todays game against the spread.

Wyoming Cowboys vs Colorado Buffaloes Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Wyoming Cowboys (2-1) are on their way to Folsom Field on Saturday, September 20, 2025 where they will take on the Colorado Buffaloes (1-2). Wyoming opens this contest as 13.0-point dogs. The over/under is set at 44. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

UAB Blazers vs Tennessee Volunteers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Tennessee Volunteers (2-1) will compete against the UAB Blazers (1-1) at Neyland Stadium on Saturday, September 20, 2025. UAB is 39.0-point underdogs. The total has been set at 67. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Florida Gators vs Miami Hurricanes Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

Hard Rock Stadium is the location where the Miami Hurricanes (3-0) will take on the Florida Gators (1-2) on Saturday, September 20, 2025. Miami opens this matchup as 7.5-point favorites. The over/under is 52. This games report has current odds, betting predictions, and free picks against the spread.

Tulsa Golden Hurricane vs Oklahoma State Cowboys Prediction, 9/19/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Boone Pickens Stadium is the site where the Oklahoma State Cowboys (1-1) will try to beat the Tulsa Golden Hurricane (1-2) on Friday, September 19, 2025. Tulsa opens this matchup as 13.0-point underdogs. The total is 54.5. This report includes betting predictions and our expert college football picks for todays game.

Maryland Terrapins vs Wisconsin Badgers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Maryland Terrapins (3-0) are en route to Camp Randall Stadium on Saturday, September 20, 2025 where they will take on the Wisconsin Badgers (2-1). Maryland is 8.5-point underdogs from Vegas oddsmakers. The over/under is set at 43.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

SMU Mustangs vs TCU Horned Frogs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The SMU Mustangs (2-1) are en route to Amon G. Carter Stadium on Saturday, September 20, 2025 where they will take on the TCU Horned Frogs (2-0). TCU opens this contest as 7.0-point favorites. The over/under is set at 64. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Temple Owls vs Georgia Tech Yellow Jackets Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Georgia Tech Yellow Jackets (3-0) will try to beat the Temple Owls (2-1) at Bobby Dodd Stadium on Saturday, September 20, 2025. Georgia Tech opens this contest as 24.0-point favorites. The over/under comes in at 52. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

BYU Cougars vs East Carolina Pirates Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The East Carolina Pirates (2-1) will compete against the BYU Cougars (2-0) at Dowdy-Ficklen Stadium on Saturday, September 20, 2025. BYU opens this matchup as 7.5-point favorites. The betting total comes in at 48. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Marshall Thundering Herd vs MTSU Blue Raiders Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Marshall Thundering Herd (1-2) are en route to Johnny "Red" Floyd Stadium on Saturday, September 20, 2025 where they will play the MTSU Blue Raiders (1-2). Marshall opens this contest as 2.5-point favorites. The total is 47. This matchup report includes betting lines and our NCAA football pick of the day for this game.

UL Monroe Warhawks vs UTEP Miners Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The UL Monroe Warhawks (1-1) are on their way to Sun Bowl on Saturday, September 20, 2025 where they will meet the UTEP Miners (1-2). UTEP opens this game as 5.0-point favorites. The total comes in at 47. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Boise State Broncos vs Air Force Falcons Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Boise State Broncos (1-1) are hitting the road to Falcon Stadium on Saturday, September 20, 2025 where they will attempt to defeat the Air Force Falcons (1-0). Air Force opens this matchup as 10.0-point underdogs. The over/under is 51.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Troy Trojans vs Buffalo Bulls Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Buffalo Bulls (2-1) will try to beat the Troy Trojans (1-2) at UB Stadium on Saturday, September 20, 2025. Buffalo opens this game as 6.0-point favorites. The total comes in at 42. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Arkansas State Red Wolves vs Kennesaw State Owls Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Arkansas State Red Wolves (1-2) are en route to Fifth Third Stadium on Saturday, September 20, 2025 where they will try to defeat the Kennesaw State Owls (1-2). Kennesaw State opens as 6.0-point underdogs. The betting total is set at 54.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Michigan Wolverines vs Nebraska Cornhuskers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Memorial Stadium is the location where the Nebraska Cornhuskers (3-0) will take on the Michigan Wolverines (2-1) on Saturday, September 20, 2025. Michigan opens this game as 2.5-point favorites. The over/under is 45. This report includes betting odds and our expert football picks for todays game.

Ball State Cardinals vs Connecticut Huskies Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Pratt & Whitney Stadium is the site where the Connecticut Huskies (1-2) will try to defeat the Ball State Cardinals (1-2) on Saturday, September 20, 2025. Ball State is 20.5-point dogs. The total comes in at 52.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Fresno State Bulldogs vs Hawaii Warriors Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Clarence T.C. Ching Athletics Complex is the location where the Hawaii Warriors (2-1) will try to beat the Fresno State Bulldogs (2-1) on Saturday, September 20, 2025. Fresno State opens this matchup as 3.0-point favorites. The betting total comes in at 47.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

California Golden Bears vs San Diego State Aztecs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Snapdragon Stadium is where the San Diego State Aztecs (1-1) will take on the California Golden Bears (2-0) on Saturday, September 20, 2025. California opens this game as 13.0-point favorites. The betting total is set at 48.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

UNLV Rebels vs Miami RedHawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The UNLV Rebels (3-0) are headed to Yager Stadium on Saturday, September 20, 2025 where they will try to defeat the Miami RedHawks (0-2). Miami opens this contest as 2.5-point dogs. The total comes in at 49. This matchup report includes Vegas odds and a free college football prediction for tonight.

Arkansas Razorbacks vs Memphis Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Memphis Tigers (3-0) welcome the Arkansas Razorbacks (2-1) at Simmons Bank Liberty Stadium on Saturday, September 20, 2025. Arkansas opens this contest as 7.5-point favorites from Vegas oddsmakers. The betting total comes in at 62.5. This matchup report includes betting lines and our NCAA football pick of the day for this game.

NC State Wolfpack vs Duke Blue Devils Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Wallace Wade Stadium is the site where the Duke Blue Devils (1-1) will try to defeat the NC State Wolfpack (3-0) on Saturday, September 20, 2025. Duke opens as 3.5-point favorites. The over/under has been set at 58. This matchup report includes Vegas odds and a free college football prediction for tonight.

Oregon State Beavers vs Oregon Ducks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Oregon State Beavers (0-3) are hitting the road to Autzen Stadium on Saturday, September 20, 2025 where they will take on the Oregon Ducks (3-0). Oregon opens this game as 35.0-point favorites. The betting total comes in at 57.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Coastal Carolina Chanticleers vs South Alabama Jaguars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Hancock Whitney Stadium is the location where the South Alabama Jaguars (1-2) will attempt to defeat the Coastal Carolina Chanticleers (1-2) on Saturday, September 20, 2025. South Alabama opens as 14.5-point favorites from Vegas oddsmakers. The betting total is set at 50.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Nevada Wolf Pack vs Western Kentucky Hilltoppers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Nevada Wolf Pack (1-2) are en route to Houchens Industries on Saturday, September 20, 2025 where they will attempt to defeat the Western Kentucky Hilltoppers (2-1). Western Kentucky opens this contest as 10.5-point favorites. The total comes in at 55.5. This games report has current odds, betting predictions, and free picks against the spread.

Stanford Cardinal vs Virginia Cavaliers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Virginia Cavaliers (2-1) welcome the Stanford Cardinal (0-2) at Scott Stadium on Saturday, September 20, 2025. Stanford opens as 15.0-point dogs from Vegas oddsmakers. The total is 49. This games report has current odds, betting predictions, and free picks against the spread.

Georgia State Panthers vs Vanderbilt Commodores Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

FirstBank Stadium is the site where the Vanderbilt Commodores (3-0) will take on the Georgia State Panthers (1-2) on Saturday, September 20, 2025. Georgia State opens this game as 26.5-point underdogs. The total is 53.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Texas Tech Red Raiders vs Utah Utes Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Utah Utes (3-0) are hosting the Texas Tech Red Raiders (3-0) at Rice-Eccles Stadium on Saturday, September 20, 2025. Texas Tech opens as 4.0-point underdogs. The total comes in at 57. This report includes betting odds and our expert football picks for todays game.

Rice Owls vs Charlotte 49ers Prediction, 9/18/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

Jerry Richardson Stadium is the location where the Charlotte 49ers (1-2) will play the Rice Owls (2-1) on Thursday, September 18, 2025. Charlotte is 2.5-point underdogs. The total comes in at 42.5. This matchup report includes college football odds, predictions, and a free pick against the spread.

Washington Huskies vs Washington State Cougars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The Washington Huskies (2-0) are en route to Martin Stadium on Saturday, September 20, 2025 where they will attempt to defeat the Washington State Cougars (2-1). Washington opens this matchup as 20.0-point favorites from oddsmakers. The total is set at 53. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

West Virginia Mountaineers vs Kansas Jayhawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Kansas Jayhawks (2-1) will take on the West Virginia Mountaineers (2-1) at David Booth Kansas Memorial Stadium on Saturday, September 20, 2025. West Virginia opens this game as 11.5-point underdogs. The total comes in at 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Sam Houston Bearkats vs Texas Longhorns Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Sam Houston Bearkats (0-3) are en route to DKR-Texas Memorial Stadium on Saturday, September 20, 2025 where they will try to defeat the Texas Longhorns (2-1). Sam Houston is 41.0-point dogs from oddsmakers. The total comes in at 51.5. This report has odds and your NCAA football predictions for todays game against the spread.

Louisiana Ragin' Cajuns vs Eastern Michigan Eagles Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Louisiana Ragin' Cajuns (1-2) are on their way to Rynearson Stadium on Saturday, September 20, 2025 where they will try to defeat the Eastern Michigan Eagles (0-3). Louisiana opens this contest as 3.0-point favorites from oddsmakers. The betting total comes in at 52. This games report has current odds, betting predictions, and free picks against the spread.

Toledo Rockets vs Western Michigan Broncos Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Western Michigan Broncos (0-3) will compete against the Toledo Rockets (2-1) at Waldo Stadium on Saturday, September 20, 2025. Western Michigan opens this game as 14.0-point underdogs. The betting total comes in at 50.5. This report has odds and your NCAA football predictions for todays game against the spread.

Michigan State Spartans vs USC Trojans Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Michigan State Spartans (3-0) are on their way to Los Angeles Memorial Coliseum on Saturday, September 20, 2025 where they will try to beat the USC Trojans (3-0). Michigan State opens this game as 17.0-point dogs. The betting total comes in at 56. This matchup report includes odds, betting predictions and a free pick against the spread.

Purdue Boilermakers vs Notre Dame Fighting Irish Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Purdue Boilermakers (2-1) are on their way to Notre Dame Stadium on Saturday, September 20, 2025 where they will meet the Notre Dame Fighting Irish (0-1). Notre Dame opens this game as 27.0-point favorites from oddsmakers. The total is 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

NIU Huskies vs Mississippi State Bulldogs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Mississippi State Bulldogs (3-0) will play the NIU Huskies (1-1) at Davis Wade Stadium on Saturday, September 20, 2025. Mississippi State is 21.5-point favorites. The over/under is 50. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

South Carolina Gamecocks vs Missouri Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

Memorial Stadium is the site where the Missouri Tigers (3-0) will try to defeat the South Carolina Gamecocks (2-1) on Saturday, September 20, 2025. South Carolina opens as 13.5-point underdogs. The over/under comes in at 46.5. This report has odds and your NCAA football predictions for todays game against the spread.

James Madison Dukes vs Liberty Flames Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Liberty Flames (1-2) will compete against the James Madison Dukes (1-1) at Williams Stadium on Saturday, September 20, 2025. Liberty opens this contest as 10.0-point dogs. The total has been set at 49. This report includes betting odds and our expert football picks for todays game.

Arizona State Sun Devils vs Baylor Bears Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Baylor Bears (2-1) are welcoming the Arizona State Sun Devils (1-1) at McLane Stadium on Saturday, September 20, 2025. Baylor opens as 2.0-point favorites. The total has been set at 60. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Tulane Green Wave vs Ole Miss Rebels Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/15/2025

The Tulane Green Wave (2-0) are hitting the road to Vaught-Hemingway Stadium on Saturday, September 20, 2025 where they will attempt to beat the Ole Miss Rebels (3-0). Ole Miss opens as 12.0-point favorites. The over/under is set at 61.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

North Carolina Tar Heels vs UCF Knights Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

The North Carolina Tar Heels (2-1) are hitting the road to FBC Mortgage Stadium on Saturday, September 20, 2025 where they will meet the UCF Knights (2-0). UCF opens this matchup as 6.5-point favorites from oddsmakers. The betting total is set at 49. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Auburn Tigers vs Oklahoma Sooners Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/15/2025

Memorial Stadium is the location where the Oklahoma Sooners (3-0) will try to defeat the Auburn Tigers (3-0) on Saturday, September 20, 2025. Oklahoma opens this contest as 7.0-point favorites from Vegas oddsmakers. The total is 48.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

UTSA Roadrunners vs Colorado State Rams Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/15/2025

The Colorado State Rams (1-1) will try to beat the UTSA Roadrunners (1-2) at Canvas Stadium on Saturday, September 20, 2025. Colorado State opens this contest as 4.5-point dogs. The over/under is set at 59.5. This matchup report includes odds, betting predictions and a free pick against the spread.

Ohio Bobcats vs Ohio State Buckeyes Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Ohio Stadium is the location where the Ohio State Buckeyes (2-0) will attempt to beat the Ohio Bobcats (1-1) on Saturday, September 13, 2025. Ohio State opens this contest as 32.0-point favorites. The over/under is set at 53. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

Arkansas Razorbacks vs Ole Miss Rebels Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Arkansas Razorbacks (2-0) are en route to Vaught-Hemingway Stadium on Saturday, September 13, 2025 where they will play the Ole Miss Rebels (2-0). Arkansas opens as 9.5-point underdogs. The total is 63. This games report has current odds, betting predictions, and free picks against the spread.