MLB Picks: Parlays, Expert Predictions, Best Bets and Player Props.

San Diego Padres vs Chicago White Sox Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/20/2025

The San Diego Padres are on the docket to play the Chicago White Sox at Rate Field on Sunday, September 21, 2025. That baseball game is set to begin at 2:10 PM EST at Rate Field in Chicago, IL. We have included an expert pick and parlay for todays game against the spread.

San Francisco Giants vs Los Angeles Dodgers Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Parlay's Pundit - 9/20/2025

The San Francisco Giants are scheduled to go head to head with the Los Angeles Dodgers at Dodger Stadium on Sunday, September 21, 2025. That encounter is scheduled to start at 4:10 PM EST at Dodger Stadium in Los Angeles, CA. We have included an expert pick and prediction for todays game against the spread.

Cleveland Guardians vs Minnesota Twins Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/20/2025

The Cleveland Guardians are set to take on the Minnesota Twins at Target Field on Sunday, September 21, 2025. That meeting is set to start at 2:10 PM EST at Target Field in Minneapolis, MN. This matchup report includes betting lines and our pick of the day for this game.

Seattle Mariners vs Houston Astros Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/20/2025

The Seattle Mariners are set to meet the Houston Astros at Daikin Park on Sunday, September 21, 2025. That tilt is set to start at 2:10 PM EST at Daikin Park in Houston, TX. This matchup report includes odds, betting trends and a free pick against the spread.

Miami Marlins vs Texas Rangers Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/20/2025

The Miami Marlins are scheduled to meet the Texas Rangers at Globe Life Field on Sunday, September 21, 2025. That contest can be observed at 2:35 PM EST at Globe Life Field in Arlington, TX. This Matchup report has your MLB pick of the day as well as MLB odds for the game.

Toronto Blue Jays vs Kansas City Royals Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/20/2025

The Toronto Blue Jays are scheduled to play the Kansas City Royals at Kauffman Stadium on Sunday, September 21, 2025. That contest can be caught at 2:10 PM EST at Kauffman Stadium in Kansas City, MO. This matchup report includes odds, betting trends and a free pick against the spread.

Washington Nationals vs New York Mets Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/20/2025

The Washington Nationals are set to take on the New York Mets at Citi Field on Sunday, September 21, 2025. That tilt can be streamed at 1:40 PM EST at Citi Field in Queens, NY. This Matchup report includes Vegas odds and a free baseball pick for tonight.

Chicago Cubs vs Cincinnati Reds Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/20/2025

The Chicago Cubs are scheduled to play the Cincinnati Reds at Great American Ball Park on Sunday, September 21, 2025. That baseball game can be viewed at 1:40 PM EST at Great American Ball Park in Cincinnati, OH. This game report has an MLB pick, betting odds, and trends for tonights key matchup.

Atlanta Braves vs Detroit Tigers Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/20/2025

The Atlanta Braves are on the docket to meet the Detroit Tigers at Comerica Park on Sunday, September 21, 2025. That game transpires at 1:40 PM EST at Comerica Park in Detroit, MI. This report includes betting odds and our expert MLB picks for todays game.

New York Yankees vs Baltimore Orioles Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/20/2025

The New York Yankees are set to go head to head with the Baltimore Orioles at Oriole Park at Camden Yards on Sunday, September 21, 2025. That game can be watched at 1:35 PM EST at Oriole Park at Camden Yards in Baltimore, MD. This games report has current odds, betting trends, and free picks against the spread.

Los Angeles Angels vs Colorado Rockies Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/20/2025

The Los Angeles Angels are set to meet the Colorado Rockies at Coors Field on Sunday, September 21, 2025. That game can be observed at 3:10 PM EST at Coors Field in Denver, CO. We have included an expert pick for todays game against the spread.

Boston Red Sox vs Tampa Bay Rays Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/20/2025

The Boston Red Sox are scheduled to meet the Tampa Bay Rays at George M. Steinbrenner Field on Sunday, September 21, 2025. That tilt transpires at 12:10 PM EST at George M. Steinbrenner Field in Tampa, FL. This report has odds and your MLB predictions for todays game against the spread.

Philadelphia Phillies vs Arizona Diamondbacks Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/20/2025

The Philadelphia Phillies are set to take on the Arizona Diamondbacks at Chase Field on Sunday, September 21, 2025. That contest occurs at 4:10 PM EST at Chase Field in Phoenix, AZ. This matchup report includes betting lines and our pick of the day for this game.

Sacramento Athletics vs Pittsburgh Pirates Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/20/2025

The Sacramento Athletics are on the docket to go head to head with the Pittsburgh Pirates at PNC Park on Sunday, September 21, 2025. That contest is set to begin at 1:35 PM EST at PNC Park in Pittsburgh, PA. This matchup report has Vegas lines and an expert MLB pick for your daily winner.

Milwaukee Brewers vs St. Louis Cardinals Prediction, 9/21/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/20/2025

The Milwaukee Brewers are scheduled to go head to head with the St. Louis Cardinals at Busch Stadium on Sunday, September 21, 2025. That game will be shown at 2:15 PM EST at Busch Stadium in St. Louis, MO. This report includes betting odds and our expert MLB picks for todays game.