Sunday Night Football Picks: Kansas City Chiefs vs Seattle Seahawks Best Bets

by Ryan Cobbett - 10/21/2026

Sunday Night Football picks for Kansas City Chiefs vs Seattle Seahawks Xavier Worthy

This week’s addition of Sunday Night Football features the undefeated Kansas City Chiefs and the defending Super Bowl Champion Seattle Seahawks. Kansas City is coming off a big division win that sinks the Chargers further down the standings. Seattle is coming off back-to-back disappointing losses where they failed to close out the game down the stretch. The Seahawks have lost three games this season, though those losses are by a combined nine points. The biggest storyline to follow in this matchup is the return of Kenneth Walker to Seattle. Walker, having been a focal point in the Super Bowl season last year, departed for Kansas City during the offseason. He has been a huge boost to the Chiefs offense, but there is no doubt Seattle will be ready to shut him down and spoil his return.

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Sunday Night Football Kansas City Chiefs vs Seattle Seahawks Game Odds:

Kansas City Chiefs: +2.5 / Moneyline: +114

Seattle Seahawks: -2.5/ Moneyline: -135

Over/Under: 42.5

Sunday Night Football Kansas City Chiefs Game Preview

The Chiefs have not yet recorded a loss on the new season. They have taken down all of their division opponents already, and they have picked up two big road wins already. This game against the Seahawks will be their biggest road test thus far, and they will need to force turnovers and play clean on offense. The Chiefs are coming off a big home win over the Los Angeles Chargers as they took them down 22-6. The Chiefs defense limited the Chargers to just 259 total yards of offense, held them to just 3.3 YPC, and they forced two turnovers. The secondary shut down Justin Herbert as he was held to just 204 passing yards on the night. Walker had himself a big night in this one as he tallied 128 rushing yards, averaged 6.7 YPC, and he recorded two touchdowns. Patrick Mahomes completed 23 of his 30 passes, but he threw an interception and failed to record a touchdown in this one. Overall, Kansas City leads the league in yards (414 YPG), and they rank fifth in PPG (28). Defensively, the Chiefs rank eighth in yards allowed (306 YPG), and they rank second in the league in points allowed (16.6 PPG).

If the Chiefs want to remain undefeated and give the defending Super Bowl Champs a losing record, they will need to force Sam Darnold to turn the ball over. Darnold has recorded seven interceptions through six games, though he has thrown just one interception in Seattle victories. The offensive line isn’t as stout as they would like it to be, and this is something George Karlaftis, and the rest of the Kansas City pass rush, will want to capitalize on. Another factor that could be a huge swing in this game will be the performance of Walker against his former team. Kansas City has relied heavily on the run game so far, but Seattle is one of just 10 teams to hold opponents to less than 100 rushing YPG. This will be a great matchup to watch Sunday night.

Kansas City Chiefs 3 Keys to Victory

Force Turnovers
Get Walker Going Against His Old Team
Limit Jaxon Smith-Njigba

Kansas City Chiefs Injuries

LB Cooper McDonald – IR

WR Rashee Rice – Questionable

OT Josh Simmons – Questionable

OT Jaylon Moore – Questionable

Sunday Night Football Seattle Seahawks Game Preview

The Seahawks are coming into this one looking to find the win column again after back-to-back losses. In their last matchup, they needed an 11-point fourth quarter to tie the game up and force overtime. Unfortunately, the magic ran out, and they fell in overtime to the Denver Broncos 17-14. Despite taking the loss, Seattle’s defense held the Broncos to just 168 yards, limiting Bo Nix to just 107 passing yards. What tells the story best, once again, is Seattle’s turnovers. They turned the ball over three times in this one and have 12 total turnovers on the year. Jaxon Smith-Njigba dominated the box score again as he totaled 134 receiving yards, with 12 receptions. Through six games, the Seattle offense has not looked as dominant as we saw last year. They are averaging 332.2 YPG and 24.7 PPG, both of which rank in the middle of the league. Defensively, they lead the league in yards allowed (237.3 YPG), and they are allowing just 20.3 PPG.

If Seattle wants to climb above .500 they will need to limit turnovers and protect Darnold. The Chiefs have a solid pass rush, so the offensive line needs to dig deep to buy their quarterback some time and keep him from getting uncomfortable. Darnold will need to be smart in his decision making and avoid making errant throws that give the Chiefs extra possessions. They could see Zach Charbonnet return to the field here which should give their run game a big boost and take some more pressure off of Darnold. On the defensive side of the ball, they need to humble Walker in his return to Seattle by making him a non-factor in this one.

Seattle Seahawks 3 Keys to Victory

Avoid Turnovers
Shut Down Kenneth Walker
Get the Ground Game Going

Seattle Seahawks Injuries

LB Chazz Surratt – Questionable

LB Drake Thomas – Questionable

G Anthony Bradford – IR

TE Elijah Arroyo – Out

RB Zach Charbonnet - Probable

Sunday Night Football Game Predictions

I like the under here for this game thanks to two strong defensive units, and due to the emphasis on the ground game between both teams. Additionally, I am going to stick with the defending Super Bowl Champs to find their way back into the win column, spoiling Walker’s return with a big performance from his former backup Charbonnet. If Charbonnet can open up the game for Darnold, it should decrease turnover potential and keep the offense from looking one dimensional like it did against Denver. The home crowd will be wild in this one and could also play a factor. Take Seattle -2.5 to end the perfect season for the Chiefs.

My Pick: Seattle Seahawks, -2.5 / Under 42.5

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Pick:	Patriots +2.5 (1H)
Start:	October 22, 2026 @ 8:15 PM
Expert:	Scott Rickenbach

Analysis:

NFL complimentary selection from Rickenbach (Football: +4,340 YTD, 18-5 Run, 10-4 Top Games YTD) for Thursday October 22nd: Your NFL complimentary selection from Rickenbach for Thursday October 22nd: Take #311 FIRST HALF New England Patriots +2.5 (1H) at Chicago (8:15 p.m.,Thursday October 22nd) - The Patriots are a 3 point dog for the game but are getting 2.5 points on the first half line. Of course a tie at the first half works just as well for us here and I like the value of this number on the first half line. New England has won 3 straight games and they are off B2B games in which they held a 14- point lead at halftime of each game! The Bears are off a big win over the Falcons but had scored an average of just 15 points in their 4 preceding games. To put that in perspective, the Patriots have scored 33 ppg in their current 3-game win streak. The Patriots most recent road game was a win at Buffalo over a tough Bills team. The Bears only 2 wins this season at home were against Eagles and Jets teams that are each having rough seasons thus far. Take New England on the first half line Thursday. Read More Read Less

Sunday Night Football Picks: Kansas City Chiefs vs Seattle Seahawks Best Bets

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