Arizona Cardinals vs Houston Texans Prediction, 12/14/2025 NFL Picks, Best Bets & Odds Week 15

Game: Arizona Cardinals vs Houston Texans

Date: Sunday, December 14, 2025

Location: NRG Stadium in Houston, TX

TV: FOX

Odds-Point Spread: Texans (-9.5)

Total-Over-Under: 42.5

NRG Stadium is the location where the Houston Texans (8-5) will meet the Arizona Cardinals (3-10) on Sunday. Houston opens this game as 9.5-point favorites from Vegas oddsmakers. The betting total comes in at 42.5.

The Arizona Cardinals head into this game 3-10 on the season. In their last contest, the Cardinals played the Los Angeles Rams and ended up losing by a score of 45-17. Zonovan Knight was the rushing leader for the Cardinals with 7 totes for 16 yds (2.3 yds per carry). Michael Wilson held an average of 12.9 yards per reception by recording 142 yds on 11 receptions. Jacoby Brissett finished 25-44 with 271 yards through the air and 2 touchdowns. He had a quarterback rate of 80.8 and finished the game with 1 interception. When it came to stopping the run, the Cardinals gave up 249 yds on 36 attempts, which is an average of 6.9 yards per run surrendered. Arizona allowed 22 pass completions on 31 tries for a total of 281 yards, and a completion rate of 71.0%. At the end of the game, they ran 58 plays for 314 yards. The Arizona Cardinals rushed the ball a total of 14 different times and accrued 51 yds, which earned them an average of 3.6 yards per carry.

The Cardinals have recorded 4,361 yards this season. Arizona has earned 171 1st downs as a team, and they have committed 96 penalties for 698 yards. In terms of putting points on the board, Arizona has accumulated 21 touchdowns via the pass and 9 rushing touchdowns. They have surrendered the ball 16 different times (8 INTs and 8 fumbles lost). Offensively, they are averaging 96.8 rush yards which ranks them 26th in the NFL. Regarding scoring touchdowns, the NFC West members are averaging 21.7 points per outing.

The Cardinals are sitting 26th in the NFL in terms of team defense, yielding 26.8 PPG. They are giving up 4.5 yards per running attempt and 123.1 rushing yds per outing over the course of the season. When talking about passing yards, the Cardinals have allowed 2,916 yards, which has them ranked 20th in football. They have conceded 224.3 yds per contest by way of the pass, and are allowing a completion percentage of 64.8%. In total, they are relinquishing 347.4 yards per game, which has them ranked 24th in professional football. They have yielded 20 touchdowns via the pass, and 15 touchdowns to runners. On the whole, they have conceded 1,600 rushing yards through 13 matchups over the course of the season.

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The Texans step on the gridiron with a record of 8-5 on the year. In their last game, the Texans walked away with a victory by a final of 20-10 against the Kansas City Chiefs. C.J. Stroud (1 touchdown) walked away from the game with 203 yards on 15-31 passing while his QB rating was 80.4. He didn't throw any picks and his avg yards per attempt was 6.5 yards. Woody Marks carried the football 26 times for 68 yards, ending the contest with 2.6 yds per attempt for Houston. Nico Collins was a featured target for the Texans, grabbing 4 passes for 121 yds (30.3 yds per reception). Houston rushed the ball for 2.6 yards per carry, totaling 82 yards on 31 attempts. The Texans finished the contest with a total of 268 yards while they ran 62 plays (4.3 yds per play). The Texans passing defense allowed a completion percentage of 42.4%, surrendering 148 yards on 14 out of 33 through the air. Houston relinquished 29 rush attempts for 126 yards (4.3 yds per carry).

If you're looking at the points being put on the board, the Texans are 20th in the league, averaging 21.8 points per outing. So far this season, the Texans have earned 2,815 pass yards and hold an average of 216.5 pass yards per contest, which ranks them 16th in the NFL. They hold an average of 105.7 rush yds per game, and have rushed for 1,374 yards. The Houston Texans have an average of 322.2 total yards per outing, putting them 20th in professional football. The Houston offense has yielded 773 yds by way of 94 infractions, which is good for 9th in the league with reference to hurting your team. They have allowed 7 picks while granting 3 fumbles lost, and have tallied 144 1st downs as a team.

The Texans are conceding 16.0 PPG, giving them a rank of 1st in the league. They have surrendered 12 touchdowns through the air plus 172.0 yards via the pass per game, giving them a rank of 3rd in the league. Houston has granted a total of 1,226 rush yds (94.3 yards per game), plus 10 touchdowns to runners over the course of this year. The Texans defense has been on the field for 746 plays, which ranks them 5th in the league. Their defense has earned 22 takeaways (7 forced fumbles and 15 INTs) over the course of the season. On the whole, they have conceded 208 points in total.

Who will win tonight's Cardinals-Texans NFL game against the spread?

Josh's Pick: Take the Cardinals +9.5

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