Arizona Cardinals vs Tampa Bay Buccaneers Prediction, 11/30/2025 NFL Picks, Best Bets & Odds Week 13
Game: Arizona Cardinals vs Tampa Bay Buccaneers
Date: Sunday, November 30, 2025
Location: Raymond James Stadium in Tampa, FL
TV: FOX
Odds-Point Spread: Buccaneers (-3)
Total-Over-Under: 44.5
Raymond James Stadium is the location where the Tampa Bay Buccaneers (6-5) will play the Arizona Cardinals (3-8) on Sunday. Arizona is 3-point underdogs. The total has been set at 44.5.
The Arizona Cardinals head into this matchup 3-8 this season. The last time they stepped on the gridiron, the Cardinals played the Jacksonville Jaguars and took a loss by a score of 27-24. Michael Carter was the best rusher for the Cardinals with 5 totes for 28 yards (5.6 yds per attempt). Michael Wilson had an average of 11.8 yards per catch by totaling 118 yds on 10 receptions. Jacoby Brissett went 33-49 with 317 yards through the air and 1 touchdown. He had a quarterback rating of 92 and walked away from the game with no picks. When it came to stopping the run, the Cardinals gave up 134 yds on 28 attempts, which is an average of 4.8 yards per run allowed. Arizona gave up 18 pass completions on 30 tries for a total of 237 yds, and a completion rate of 60.0%. When all was said and done, they tallied 70 plays for 326 yds. The Arizona Cardinals ended up running the ball 20 different times and recorded 55 yds, which had them averaging 2.8 yards per tote.

When examining notching touchdowns, the Cardinals are averaging 22.5 points per outing. As a unit, they have an average of 101.1 running yards which is 25th in the league. The Cardinals have collected 3,661 total yards over the course of this year. Arizona has recorded 140 first downs as an offense, and they have been called for 85 penalties for 623 yds. They have given the ball away 13 different times (6 picks and 7 fumbles). If you analyze getting the ball in the endzone, Arizona has compiled 17 touchdowns via the pass and 9 ground TD's.
The Cardinals are ranked 24th in professional football when it comes to opponents scoring, yielding 25.7 points per contest. The opposition is running for an average of 4.3 yds per rush and 114.2 running yards per outing for the year. If you analyze yards via the pass, the Cardinals have relinquished 2,451 total yards, which ranks 18th in the league. They have relinquished 222.8 yds per contest by way of the pass, and are conceding a completion% of 64.3%. All in all, they are granting 337.0 yds per game, which is 19th in the league. They have given up 16 touchdowns through the air, as well as 11 touchdowns by way of the ground game. Overall, they have allowed 1,256 yards on the ground through 11 games over the course of this year.
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The Buccaneers step onto the field with a record of 6-5 on the year. When they last took the field, the Buccaneers took a defeat with a final score of 34-7 against the Los Angeles Rams. Baker Mayfield (1 touchdown) ended the contest with 41 yards on 9-19 passing while his quarterback rating was 32. He threw 2 interceptions and his average yards per pass attempt was 2.2 yards. Sean Tucker ran the ball 12 times for 42 yards, ending the contest with 3.5 yds per carry for Tampa Bay. Cade Otton was a featured target for the Buccaneers, bringing in 4 balls for 21 yards (5.3 yards per catch). Tampa Bay ended up running for 4.2 yds per attempt, finishing with a total of 123 yds on 29 attempts. The Buccaneers finished the game with 193 yds while they ran 63 plays (3.1 yds per play). The Buccaneers pass defense allowed a completion percentage of 71.4%, relinquishing 263 yds on 25 out of 35 passing. Tampa Bay gave up 19 rush attempts for 70 yards (3.7 yds per rush).
The Tampa Bay Buccaneers average 319.5 total yards per contest, which is good for 20th in professional football. They hold an average of 111.2 running yards per game, and have run for 1,223 yds. They have recorded 5 interceptions while yielding 4 fumbles lost, and have obtained 111 1st downs as an offense. The Tampa Bay offense has granted 477 yds on 60 penalty flags, which is 31st in the league when examining giving up free yards. In this campaign, the Buccaneers have a total of 2,292 yards through the air and are averaging 208.4 yards through the air per contest, which is good for 19th in professional football. When examining their scoring prowess, the Buccaneers are ranking 14th in professional football, holding an average of 23.5 points per outing.
They have given up 19 touchdowns by way of the pass in addition to 243.5 pass yds per outing, which has them sitting 27th in the league. Tampa Bay has granted a total of 1,074 rush yards (97.6 yards per contest), along with 12 touchdowns on the ground this season. The defense has compiled 16 turnovers (6 fumbles forced and 10 INTs) for the year. In total, they have given up 284 pts. The Buccaneers defense has taken the field for 662 plays, which has them sitting 8th in the league. The Buccaneers are surrendering 25.8 points per contest, which is good for 25th in professional football.
Who will win tonight's Cardinals-Buccaneers NFL game against the spread?
Tony's Pick: Take the Buccaneers -3
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