Atlanta Falcons vs Indianapolis Colts Prediction, 11/9/2025 NFL Picks, Best Bets & Odds Week 10

Game: Atlanta Falcons vs Indianapolis Colts

Date: Sunday, November 9, 2025

Location: Olympic Stadium in Berlin, Germany

TV: NFL Net NFL+

Odds-Point Spread: Colts (-6)

Total-Over-Under: 48.5

The Atlanta Falcons (3-5) are en route to Olympic Stadium on Sunday where they will compete against the Indianapolis Colts (7-2). Atlanta is 6-point underdogs from Vegas oddsmakers. The over-under is set at 48.5.

The Atlanta Falcons step on the gridiron holding a record of 3-5 on the year. The last time they stepped on the gridiron, the Falcons took on the New England Patriots and walked away from this one with a loss by a score of 24-23. Michael Penix went 22-37 with 221 yds passing and 3 TDs. He had a QB rate of 103.5 and finished the game without throwing a pick. Drake London held an average of 13.1 yds per catch by accumulating 118 yards on 9 catches. Bijan Robinson was the best rusher for the Falcons with 12 carries for 46 yards (3.8 yds per attempt). On the day, they had 53 plays which gave them 288 yards. The Atlanta Falcons rushed the ball a total of 16 different times and recorded 71 yds, earning them an average of 4.4 yards per carry. When it came to stopping the run, the Falcons conceded 110 yards on 33 attempts, which is an average of 3.3 yds per rush surrendered. Atlanta surrendered 19 pass completions on 29 tries for a total of 221 yds, and a completion rate of 65.5%.

The Falcons have attained 2,687 total yards this season. Atlanta has accumulated 89 1st downs, and they have committed 46 penalties for 346 total yards. When it comes to getting the ball into the endzone, Atlanta has notched 8 passing TD's and 7 touchdowns on the ground. They have turned the football over 7 different times (3 INTs and 4 fumbles). Collectively, they're averaging 116.8 running yards which has them sitting 15th in football. If you look at notching touchdowns, the NFC South members average 17.9 points per outing.

The Falcons are ranking 13th in professional football when examining the opposition scoring, yielding 22.3 PPG. The opposition is running for an average of 4.4 yards per running attempt and 124.4 rushing yds per outing over the course of the season. Regarding pass yds, the Falcons have relinquished 1,265 total yards, which has them sitting 1st in the NFL. They have given up 158.1 yards per contest by way of the pass, and are yielding a completion% of 62.3%. All in all, they are granting 282.5 yards per contest, putting them 4th in professional football. They have given up 13 touchdowns through the air, and 5 touchdowns via the rush. All in all, they have conceded 995 yards via the running game in 8 contests over the course of the season.

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The Colts step onto the field with a record of 7-2 over the course of the season. In their last game, the Colts took a defeat with a final score of 27-20 when they faced the Pittsburgh Steelers. Jonathan Taylor carried the football 14 times for 45 yards, ending the contest with 3.2 yds per carry for Indianapolis. Alec Pierce was a featured target for the Colts, snagging 6 passes for 115 yds (19.2 yards per catch). Daniel Jones (1 TD) finished the game with 342 yards on 31-50 passing while his QB rating was 63.9. He threw 3 picks and his average yards per pass attempt was 6.8 yds. Indianapolis surrendered 23 attempts on the ground for 38 yards (1.7 yds per carry). The Colts pass defense gave up a completion rate of 71.4%, surrendering 187 yds on 25 out of 35 through the air. The Colts finished the game with a total of 368 yards on 69 plays (5.3 yards per play). Indianapolis ran for 2.9 yards per attempt, finishing the contest with 55 yards on 19 attempts.

The Indianapolis Colts average 383.3 yards per contest, which ranks them 2nd in the league. They average 125.6 running yards per contest, and have toted the ball for 1,130 yds. They have allowed 6 INTs while giving up 4 fumbles, and have been able to tally 121 1st downs. The Indianapolis offense has granted 468 yards on 55 violations, which is 17th in football if you analyze making mistakes. This year, the Colts have thrown for 2,320 yards via the pass and average 257.8 yards via the pass per contest, giving them a rank of 2nd in the NFL. If you look at the points being put on the board, the Colts are sitting 1st in the NFL, with an average of 32.2 points per contest.

They have relinquished 15 touchdowns by way of the pass and 244.8 yards via the pass per contest, which has them sitting 26th in football. Indianapolis has granted a total of 783 running yds (87.0 total yards per outing), and 6 touchdowns via the rush this season. The defense has a total of 13 takeaways (3 forced fumbles and 10 INTs) over the course of this year. In total, they have relinquished 181 total points. The Colts defense has been on the field for 572 plays from the line of scrimmage, which ranks them at 29th in the NFL. The Colts are yielding 20.1 points per game, which has them sitting 7th in the NFL.

Who will win tonight's Falcons-Colts NFL game against the spread?

Guy's Pick: Take the Colts -6

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