Carolina Panthers vs New Orleans Saints Prediction, 12/14/2025 NFL Picks, Best Bets & Odds Week 15
Game: Carolina Panthers vs New Orleans Saints
Date: Sunday, December 14, 2025
Location: Caesars Superdome in New Orleans, LA
TV: FOX
Odds-Point Spread: Saints (+2.5)
Total-Over-Under: 40.5
Caesars Superdome is the place where the New Orleans Saints (3-10) will attempt to defeat the Carolina Panthers (7-6) on Sunday. New Orleans opens this matchup as 2.5-point underdogs from Vegas oddsmakers. The betting total is set at 40.5.
The Carolina Panthers step onto the field holding a record of 7-6 on the campaign. In their last contest, the Panthers went up against the Los Angeles Rams and walked away with a win by a score of 31-28. Rico Dowdle was the leader on the ground for the Panthers with 18 attempts for 58 yards (3.2 yards per attempt). Jalen Coker averaged 18.5 yds per reception by totaling 74 yards on 4 catches. Bryce Young connected on 15-20 with 206 yds passing and 3 TDs. He had a quarterback rating of 147.1 and finished the game with no picks. On the ground, the Panthers gave up 152 yds on 21 tries, which is an average of 7.2 yards per run surrendered. Carolina conceded 18 pass completions on 28 tries for 227 yards, and a completion percentage of 64.3%. Once the final whistle blew, they tallied 60 plays which totaled 358 yds. The Carolina Panthers ran the football 40 times and amassed 164 yards, which is an average of 4.1 yds per attempt.

The Panthers have compiled 4,045 yards for this campaign. Carolina has collected 138 1st downs, and they have committed 71 infractions for 563 yards. When examining scoring points, Carolina has earned 19 passing touchdowns and 7 running touchdowns. They have coughed up the ball 17 different times (10 INTs and 7 fumbles). Offensively, they are averaging 125.5 rush yards which ranks them 10th in the NFL. Concerning getting the ball into the endzone, the NFC members are sitting at 19.0 points per contest.
The Panthers sit 16th in the league when talking about the other team scoring points, yielding 22.8 points per game. They are allowing 4.5 yards per rush and 118.7 rushing yds per outing on the season. When analyzing pass yards, the Panthers have relinquished 2,761 yards, which ranks them 18th in the NFL. They have surrendered 212.4 yards per contest by way of the pass, and are yielding a completion% of 65.2%. On the whole, they are conceding 331.1 yards per contest, which ranks them 18th in the NFL. They have yielded 16 touchdowns via the pass, as well as 16 touchdowns to runners. On the whole, they have conceded 1,543 rushing yards through 13 contests this season.
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The Saints come into this matchup holding a record of 3-10 this year. When they last stepped on the football field, the Saints went home victorious with a score of 24-20 when they played the Tampa Bay Buccaneers. Tyler Shough ended the contest with 144 yards on 13-20 through the air while his QB rating was 65.4. He had 1 pick and his average yards per pass attempt was 7.2 yards. Devin Neal carried the ball 19 times for 70 yards, finishing the contest with 3.7 yards per carry for New Orleans. Juwan Johnson was featured in the passing game for the Saints, hauling in 4 throws for 38 yds (9.5 yards per reception). New Orleans rushed the ball for 4.3 yds per carry, finishing the contest with 139 yds on 32 carries. The Saints finished the contest with a total of 260 yards and they ran 52 plays (5.0 yds per play). The Saints secondary conceded a completion percentage of 46.7%, surrendering 122 yards on 14 out of 30 passing. New Orleans gave up 39 attempts on the ground for 179 yards (4.6 yds per rush).
The New Orleans Saints average 293.8 yards per contest, which ranks them 26th in the league. They have an average of 94.4 rushing yards per contest, and have toted the ball for 1,227 yards. They have allowed 11 picks while granting 9 fumbles lost, and have tallied 131 1st downs as a team. The New Orleans offense has relinquished 688 yards on 94 penalties, which has them ranked 10th in football when examining helping out the other team. For the season, the Saints sit at 2,592 yards through the air and are sitting at 199.4 yards through the air per game, which has them ranked 21st in professional football. When talking about their scoring prowess, the Saints sit 30th in football, scoring 15.8 points per outing.
They have relinquished 21 touchdowns through the air as well as 182.6 yards through the air per game, which has them ranked 6th in professional football. New Orleans has granted a total of 1,702 rush yds (130.9 yards per game), plus 11 touchdowns to runners over the course of this year. The defense has earned 15 takeaways (7 fumbles forced and 8 INTs) this year. All in all, they have allowed 315 pts. The Saints defense has been on the field for 801 plays, which is good for 16th in the league. The Saints are granting 24.2 points per outing, giving them a rank of 21st in pro football.
Who will win tonight's Panthers-Saints NFL game against the spread?
Josh's Pick: Take the Saints +2.5
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Additional Resources:
New Orleans Saints - Twitter
Carolina Panthers - Twitter

