Chicago Bears vs Detroit Lions Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
Game: Chicago Bears vs Detroit Lions
Date: Sunday, September 14, 2025
Location: Ford Field in Detroit, MI
TV: FOX
Odds-Point Spread: Lions (-6)
Total-Over-Under: 47.5
The Chicago Bears (0-1) are hitting the road to Ford Field on Sunday where they will attempt to defeat the Detroit Lions (0-1). Detroit opens this game as 6-point favorites from Vegas oddsmakers. The total comes in at 47.5.
The Chicago Bears step on the gridiron 0-1 over the course of this season. In their last game, the Bears played against the Minnesota Vikings and ended up losing by a score of 27-24. Caleb Williams went 21-35 with 210 yds passing and 1 TD. He had a QB rating of 86.6 and finished the contest without throwing an interception. D'Andre Swift was the rushing leader for the Bears with 17 totes for 53 yds (3.1 yds per carry). Rome Odunze left with an average of 6.2 yards per catch by accumulating 37 yds on 6 catches. The Chicago Bears ended up running the ball 26 times and accumulated 119 yards, which came out to an average of 4.6 yds per attempt. At the end of the game, they ran 61 plays which converted into 317 yds. Chicago gave up 13 pass completions on 20 attempts for a total of 134 yards, and a completion percentage of 65.0%. Against the rush, the Bears conceded 120 yards on 26 attempts, which is 4.6 yds per rush allowed.

The Bears have tallied 317 yards over the course of the season. Chicago has notched 10 first downs as a unit, and they have committed 12 penalties for 127 yards. When it comes to getting in the endzone, Chicago has earned 1 passing touchdown and 1 rushing touchdown. They have surrendered the ball 1 time. Collectively, they're maintaining an average of 119.0 rush yards ranking them 10th in the NFL. If you look at putting the ball in the endzone, the NFC North members are sitting at 24.0 points per game.
When examining pass yds, the Bears have conceded 134 yds, ranking them 5th in the NFL. They are granting a completion% of 65.0%. They have conceded 2 touchdowns by way of the pass, in addition to 1 touchdown on the ground. On the whole, they are conceding 254.0 yds per game, putting them 7th in pro football. They are allowing an average of 4.6 yards per run and 120.0 rushing yards per game for the year. The Bears currently sit 27th in pro football in terms of their defensive abilities, conceding 27.0 PPG.
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The Lions come into this game with a record of 0-1 for this campaign. When they last stepped on the football field, the Lions went home defeated by a final of 27-13 against the Green Bay Packers. Jared Goff (1 TD) finished the game with 225 yds on 31-39 through the air while his quarterback rating was 88.6. He threw 1 pick and his avg yards per attempt was 5.8 yds. Jahmyr Gibbs was featured in the passing game for the Lions, bringing in 10 passes for 31 yards (3.1 yds per catch). David Montgomery carried the ball 11 times for 25 yards, ending the contest with 2.3 yards per carry for Detroit. The Lions finished the game with a total of 246 yards while they ran 61 plays (4.0 yards per play). Detroit ended up running for 2.1 yards per carry, finishing with a total of 46 yards on 22 attempts. Detroit conceded 25 rushing attempts for 78 yards (3.1 yds per carry). The Lions secondary conceded a completion rate of 72.7%, relinquishing 188 yards on 16 out of 22 passing.
When examining their ability to score points, the Lions are 27th in the NFL, by tallying 13.0 points per outing. This year, the Lions sit at 200 pass yards which is 15th in football. They have toted the ball for 46 total yards. The Detroit Lions hold an average of 246.0 yds per game, putting them 27th in pro football. The Detroit offense has yielded 40 total yards by way of 7 penalties, ranking them 20th in pro football when analyzing making mistakes.
The Lions are yielding 27.0 points per game, which has them ranking 26th in the league. They have surrendered 2 touchdowns through the air in addition to 188.0 pass yards per contest, putting them 15th in pro football. Detroit has allowed a total of 78 running yds. The Lions defense has taken the field for 47 plays, putting them 2nd in pro football. Their defense has yet to take the ball away.
Who will win tonight's Bears-Lions NFL game against the spread?
Parlays Pundit's Pick: Take the Lions -6 and over 47.5 total points
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Additional Resources:
Detroit Lions - Twitter
Chicago Bears - Twitter