Cincinnati Bengals vs Cleveland Browns Prediction, 9/7/2025 NFL Picks, Best Bets & Odds Week 1

Game: Cincinnati Bengals vs Cleveland Browns

Date: Sunday, September 7, 2025

Location: Huntington Bank Field in Cleveland, OH

TV: FOX

Odds-Point Spread: Browns (+5.5)

Total-Over-Under: 47.5

Huntington Bank Field is where the Cleveland Browns (3-14 last year) will meet the Cincinnati Bengals (9-8 last season) on Sunday. Cincinnati opens this matchup as 5.5-point favorites from oddsmakers. The total is set at 47.5.

The Cincinnati Bengals finished the year having notched a 9-8 record. When they last took the field, the Bengals played the Pittsburgh Steelers and took home the win by a score of 19-17. Khalil Herbert was the best rusher for the Bengals with 20 carries for 69 yards (3.5 yds per carry). Ja'Marr Chase left with an average of 9.6 yds per reception by earning 96 yards on 10 catches. Joe Burrow went 37-46 with 277 yds passing and 1 touchdown. He had a quarterback rating of 89.9 and finished the game with 1 pick. In the running game, the Bengals gave up 74 yds on 23 attempts, which averages out to 3.2 yards per run allowed. Cincinnati conceded 17 pass completions on 31 tries for a total of 119 yds, and a completion percentage of 54.8%. In all, they tallied 67 plays which gave them a total of 314 yards. The Cincinnati Bengals rushed the ball a total of 21 times and accounted for 68 yds, which came out to an average of 3.2 yards per carry.

The Bengals notched 6,214 yds for the previous season. Cincinnati compiled 253 first downs as a team, and they were flagged for 101 penalties for 780 yds. Cincinnati earned 43 passing touchdowns and 11 ground TD's. They surrendered the football 22 different times (9 interceptions and 13 fumbles lost). As a unit, they maintained an average of 92.6 rushing yards, which had them ranking 30th in football. When analyzing getting in the endzone, the AFC representatives averaged 27.8 points per outing.

When analyzing passing yds, the Bengals allowed 3,799 yds which had them ranking 21st in professional football. They surrendered 223.5 yards per contest via the pass, and conceded a completion rate 64.9%. They allowed 30 passing TD's, along with 20 via the rush. In total, they conceded 348.3 per contest, ranking them 25th in football. They allowed an average of 4.4 yds per rush on the ground and 124.8 rushing yards per contest for the prior campaign. The Bengals sat 25th in football when analyzing their defensive prowess, granting 25.5 points per contest. Altogether, they relinquished 2,122 yards via the running game in 17 matchups in the previous season.

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The Browns ended the year having amassed a 3-14 mark. The last time they stepped on the gridiron, the Browns went home defeated by a final of 35-10 when they played the Baltimore Ravens. D'Onta Foreman ran the ball 10 times for 27 yds, ending the game with 2.7 yards per attempt for Cleveland. Jerry Jeudy was the best receiver for the Browns, bringing in 6 throws for 63 yards (10.5 yds per catch). Bailey Zappe (1 touchdown) finished the game with 170 yds on 16-31 through the air while his QB rate was 51.8. He tossed 2 interceptions and his average yds per pass attempt was 5.5 yds. Cleveland surrendered 35 attempts on the ground for 220 yds (6.3 yards per rush). The Browns pass defense allowed a completion rate of 50.0%, surrendering 217 yards on 16 for 32 through the air. The Browns finished with a total of 230 yards while running 53 plays (4.3 yds per play). Cleveland rushed the football for 2.9 yards per carry, finishing with 56 yds on 19 carries.

The Cleveland Browns averaged 300.8 yds per game, putting them 28th in football. They averaged 94.6 rush yards per outing, and toted the ball for 1,608 total yards. The Cleveland offense surrendered 915 yds on 119 violations, which had them ranked 7th in the NFL when it comes to making mistakes. For the previous season, the Browns had a previous total of 3,506 pass yards and averaged 206.2 pass yards per contest, which had them ranking 22nd in football. If you're looking at their ability to score points, the Browns were sitting 32nd in the NFL, holding an average of 15.2 points per contest.

The Browns allowed 25.6 points per outing, which was 27th in professional football. They relinquished 26 touchdowns by way of the pass along with 212.4 yards through the air per contest, ranking them 12th in football. Cleveland yielded a total of 2,205 rushing yards (129.7 yards per contest), as well as 22 touchdowns via the rush for the prior campaign. The Browns defense was on the field for 1,040 plays from the line of scrimmage, which had them ranking 12th in professional football. Their defense accumulated 12 turnovers (8 fumbles forced and 4 interceptions) for the previous season.

Who will win tonight's Bengals-Browns NFL game against the spread?

Parlays Pundit's Pick: Take the Browns +5.5 and over 47.5 total points

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