Cleveland Browns vs Pittsburgh Steelers Prediction, 10/12/2025 NFL Picks, Best Bets & Odds Week 6

Game: Cleveland Browns vs Pittsburgh Steelers

Date: Sunday, October 12, 2025

Location: Acrisure Stadium in Pittsburgh, PA

TV: CBS

Odds-Point Spread: Steelers (-5)

Total-Over-Under: 38.5

The Pittsburgh Steelers (3-1) will compete against the Cleveland Browns (1-4) at Acrisure Stadium on Sunday. Pittsburgh opens this contest as 5-point favorites from oddsmakers. The total has been set at 38.5.

The Cleveland Browns step on the gridiron 1-4 for the year. The last time they took the field, the Browns played the Minnesota Vikings and took a loss by a final of 21-17. Quinshon Judkins was the rushing leader for the Browns with 23 totes for 110 yds (4.8 yds per attempt). David Njoku held an average of 11.2 yds per reception by earning 67 yards on 6 catches. Dillon Gabriel went 19-33 with 190 yds passing and 2 touchdowns. He had a quarterback rate of 94.3 and ended the game with no interceptions. On the ground, the Browns gave up 97 yards on 23 tries, which averages out to 4.2 yards per run allowed. Cleveland allowed 26 pass completions on 35 attempts for a total of 252 yds, and a completion rate of 74.3%. When the final whistle blew, they had 65 plays which gave them 322 yards. The Cleveland Browns ended up rushing 32 times and accumulated 140 yds, which came out to an average of 4.4 yds per carry.

The Browns have accumulated 1,441 total yards over the course of the season. Cleveland currently has 47 first downs, and they have been called for 37 penalties for 307 yds. In terms of putting the ball in the endzone, Cleveland has recorded 5 passing TD's and 3 rushing touchdowns. They have turned the football over 8 times (6 interceptions and 2 lost fumbles). Collectively, they average 95.8 running yards which is 26th in professional football. In terms of putting the ball in the endzone, the Browns average 14.6 points per game.

With reference to pass yards, the Browns have conceded 861 yds, which is 7th in football. They have granted 172.2 yds per outing through the air, and are surrendering a completion percentage of 66.9%. In total, they have yielded 378 yards via the running game in 5 contests over the course of the season. They have relinquished 10 touchdowns by way of the pass, along with 3 touchdowns by way of the ground game. Altogether, they are giving up 247.8 total yards per outing, ranking this team at 2nd in the NFL. Opposing teams are running for an average of 3.0 yds per rush on the ground and 75.6 rush yds per outing for the year. The Browns are 21st in professional football when it comes to the other team scoring points, granting 24.6 points per contest.

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The Steelers come into this matchup holding a record of 3-1 for the year. When they last took the field, the Steelers got the victory with a final of 24-21 when they played the Minnesota Vikings. Aaron Rodgers (1 TD) finished the game with 200 yds on 18-22 through the air while his QB rating was 119.7. He didn't toss any interceptions and his average yds per pass attempt was 9.1 yds. Kenneth Gainwell carried the rock 19 times for 99 yards, finishing the contest with 5.2 yds per carry for Pittsburgh. Kenneth Gainwell was a featured target for the Steelers, catching 6 throws for 35 yards (5.8 yds per reception). Pittsburgh rushed for 4.5 yds per attempt, finishing the game with 131 yds on 29 attempts. The Steelers ended up finishing with 313 yards while running 51 plays (6.1 yards per play). The Steelers passing defense gave up a completion rate of 65.2%, relinquishing 302 yards on 30 for 46 passing. Pittsburgh relinquished 20 run attempts for 70 yards (3.5 yards per rush).

The Pittsburgh Steelers hold an average of 263.5 total yards per contest, which has them sitting 29th in professional football. They hold an average of 80.0 running yards per game, and have carried the ball for 320 yards. They have a total of 3 interceptions while allowing 0 fumbles lost, and have tallied 31 1st downs as an offense. The Pittsburgh offense has yielded 135 yds on 19 penalties, giving them a rank of 32nd in football if you examine helping out the opposition. This year, the Steelers have a total of 734 yards via the pass and are averaging 183.5 yards via the pass per outing, ranking this team at 27th in the NFL. With reference to how much they score, the Steelers are ranking 17th in football, holding an average of 24.0 points per outing.

The Steelers are allowing 24.5 points per contest, putting them 20th in the league. They have given up 7 touchdowns via the pass plus 260.5 yards through the air per outing, ranking them 30th in the NFL. Pittsburgh has conceded a total of 488 rushing yds (122.0 total yards per outing), plus 4 touchdowns to rushers over the course of this year. The Steelers defense has been on the field for 269 plays, which has them sitting 4th in professional football. The defense has produced 10 turnovers (5 forced fumbles and 5 picks) for this campaign. On the whole, they have given up 98 total points.

Who will win tonight's Browns-Steelers NFL game against the spread?

Guy's Pick: Take the Browns +5

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