Denver Broncos vs Philadelphia Eagles Prediction, 10/5/2025 NFL Picks, Best Bets & Odds Week 5
Game: Denver Broncos vs Philadelphia Eagles
Date: Sunday, October 5, 2025
Location: Lincoln Financial Field in Philadelphia, PA
TV: CBS
Odds-Point Spread: Eagles (-4.5)
Total-Over-Under: 44
Lincoln Financial Field is the place where the Philadelphia Eagles (4-0) will take on the Denver Broncos (2-2) on Sunday. Denver is 4.5-point underdogs. The betting total is set at 44.
The Denver Broncos step onto the field holding a record of 2-2 on the year. The last time they stepped on the gridiron, the Broncos played the Cincinnati Bengals and walked away with a win by a score of 28-3. J.K. Dobbins was the rushing leader for the Broncos with 16 attempts for 101 yds (6.3 yards per attempt). Marvin Mims held an average of 11.5 yards per catch by tallying 69 yds on 6 catches. Bo Nix connected on 29-42 with 326 yds through the air and 2 touchdowns. He had a QB rate of 97.9 and ended the game with 1 pick. When it came to the battle of the line of scrimmage, the Broncos gave up 53 yards on 15 attempts, which is an average of 3.5 yards per rush allowed. Denver conceded 14 pass completions on 25 tries for 106 yards, and a completion rate of 56.0%. In all, they ran 80 plays which gave them a total of 512 yds. The Denver Broncos rushed the ball a total of 38 times and accrued 186 yds, which came out to an average of 4.9 yards per carry.

If you analyze getting in the endzone, the Broncos hold an average of 24.0 PPG. Offensively, they're sitting at 143.3 rushing yards putting them 5th in football. The Broncos have attained 1,418 total yards this year. Denver has tallied 42 first downs as a team, and they have been hurt by 31 infractions for 290 total yards. They have given the ball to the opposition 6 different times (4 INTs and 2 fumbles). In terms of scoring, Denver has attained 7 touchdowns via the pass and 5 touchdowns via the run.
Regarding yards through the air, the Broncos have conceded 744 total yards, putting them 9th in the league. They have granted 186.0 yds per contest via the pass, and are giving up a completion percentage of 57.5%. In total, they have surrendered 397 yards on the ground through 4 outings for the year. They have allowed 2 touchdowns via the pass, plus 2 touchdowns to rushers. All in all, they are giving up 285.3 yds per contest, which ranks them 10th in pro football. The opposition is running for an average of 4.1 yards per rush and 99.3 rushing yds per game for the year. The Broncos are sitting 3rd in football when it comes to their defensive abilities, granting 16.8 points per outing.
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The Eagles come into this game with a record of 4-0 for the season. The last time they stepped on the gridiron, the Eagles walked away with a victory by a final of 31-25 when they played the Tampa Bay Buccaneers. Saquon Barkley ran the football 19 times for 43 yds, finishing the game with 2.3 yds per carry for Philadelphia. Saquon Barkley was a featured target for the Eagles, hauling in 4 passes for 31 yards (7.8 yards per reception). Jalen Hurts (2 touchdowns) walked away from the contest with 130 yards on 15-24 through the air while his QB rate was 104.5. He didn't toss any interceptions and his Y-A was 5.4 yds. Philadelphia allowed 26 rush attempts for 104 yards (4.0 yds per rush). The Eagles secondary allowed a completion rate of 55.0%, relinquishing 272 yards on 22 for 40 through the air. The Eagles finished the game with 200 yds on 56 plays (3.6 yards per play). Philadelphia rushed the ball for 2.8 yards per carry, finishing the game with 88 yds on 32 attempts.
Concerning their ability to score points, the Eagles are sitting 7th in football, by tallying 27.0 points per outing. In this season, the Eagles have earned 552 passing yds and hold an average of 138.0 passing yds per outing, which has them ranked 31st in pro football. They maintain an average of 113.5 rushing yards per contest, and have run for 454 yards. The Philadelphia Eagles average 251.5 yds per contest, which has them ranked 30th in the NFL. The Philadelphia offense has surrendered 291 total yards by way of 28 penalty flags, which is good for 19th in professional football regarding helping out the other team. They have tossed 0 picks while allowing 1 fumble, and have been able to record 29 first downs as a team.
The Eagles are relinquishing 22.0 points per game, which is good for 16th in professional football. They have surrendered 5 touchdowns via the pass in addition to 207.3 passing yds per game, which is good for 18th in professional football. Philadelphia has conceded a total of 504 rushing yards (126.0 yards per contest), as well as 3 touchdowns via the rush on the year. The Eagles defense has been on the field for 247 plays from scrimmage, which is 21st in football. Their defense has accrued 5 turnovers (2 fumbles forced and 3 interceptions) over the course of this year. Overall, they have given up 88 total points.
Who will win tonight's Broncos-Eagles NFL game against the spread?
Josh's Pick: Take the Eagles -4.5
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Additional Resources:
Philadelphia Eagles - Twitter
Denver Broncos - Twitter