Detroit Lions vs Kansas City Chiefs Prediction, 10/12/2025 NFL Picks, Best Bets & Odds Week 6

Game: Detroit Lions vs Kansas City Chiefs

Date: Sunday, October 12, 2025

Location: GEHA Field at Arrowhead Stadium in Kansas City, MO

TV: NBC

Odds-Point Spread: Chiefs (+1)

Total-Over-Under: 50.5

GEHA Field at Arrowhead Stadium is the location where the Kansas City Chiefs (2-3) will play the Detroit Lions (4-1) on Sunday. Kansas City is 1-point underdogs from oddsmakers. The over-under has been set at 50.5.

The Detroit Lions step on the gridiron 4-1 for the year. In their last game, the Lions faced off with the Cincinnati Bengals and went home with a win by a final score of 37-24. Jared Goff finished 19-23 with 258 yards passing and 3 touchdowns. He had a quarterback rating of 153 and finished the game without throwing an interception. David Montgomery was the rushing leader for the Lions with 18 carries for 65 yards (3.6 yds per carry). Amon-Ra St. Brown had an average of 12.5 yds per reception by notching 100 yds on 8 receptions. The Detroit Lions ran the football 33 times and accumulated 118 yards, which earned them an average of 3.6 yards per attempt. Once the final whistle blew, they tallied 57 plays which totaled 365 yds. Detroit relinquished 26 pass completions on 40 attempts for 237 yds, and a completion rate of 65.0%. Against the rush, the Lions gave up 85 yards on 16 attempts, which is 5.3 yards per run allowed.

The Lions have accrued 1,825 yds for the year. Detroit has recorded 62 first downs, and they have been hurt by 32 penalties for 227 total yards. If you're looking at putting points on the board, Detroit has produced 13 passing touchdowns and 8 ground TD's. They have surrendered the ball 3 different times (2 picks and 1 fumble). Offensively, they're holding an average of 134.8 rushing yards putting them 7th in pro football. If you analyze getting the ball into the endzone, the team residing in Detroit are averaging 34.8 points per contest.

The Lions currently rank 17th in football when talking about their opponents scoring, allowing 22.4 PPG. They are allowing 4.0 yds per run and 92.2 rushing yards per outing for the year. If you're looking at pass yards, the Lions have relinquished 1,033 total yards, which ranks them at 13th in football. They have conceded 206.6 total yards per outing through the air, and are giving up a completion percentage of 63.3%. In total, they are surrendering 298.8 yds per outing, which is 8th in football. They have granted 10 touchdowns via the pass, as well as 4 touchdowns on the ground. In total, they have conceded 461 yards via the ground game in 5 games on the campaign.

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The Chiefs step on the gridiron with a record of 2-3 for the year. When they last took the field, the Chiefs took a defeat with a final score of 31-28 when they played the Jacksonville Jaguars. Kareem Hunt carried the rock 7 times for 49 yards, ending the contest with 7.0 yds per carry for Kansas City. Travis Kelce was a featured target for the Chiefs, bringing in 7 passes for 61 yds (8.7 yards per reception). Patrick Mahomes (1 TD) ended the game with 318 yds on 29-41 through the air while his QB rating was 91.3. He threw 1 pick and his average yards per pass attempt was 7.8 yards. Kansas City conceded 26 attempts on the ground for 109 yards (4.2 yds per carry). The Chiefs passing defense conceded a completion rate of 72.0%, relinquishing 210 yards on 18 out of 25 through the air. The Chiefs finished the game with 476 yards while running 63 plays (7.6 yards per play). Kansas City rushed the ball for 7.2 yards per attempt, finishing the contest with 158 yards on 22 carries.

The Kansas City Chiefs have an average of 361.0 yds per game, putting them 8th in the league. They hold an average of 120.0 running yards per game, and have carried the ball for 600 yards. They have tossed 2 picks while granting 0 fumbles lost, and have been able to record 59 1st downs as a unit. The Kansas City offense has yielded 350 yds by way of 42 violations, which is 7th in football with reference to helping out the opposition. This year, the Chiefs have a total of 1,205 yards via the pass and are averaging 241.0 yards via the pass per outing, ranking this team at 9th in the NFL. In terms of how much they score, the Chiefs currently rank 14th in pro football, with an average of 25.0 points per game.

The Chiefs are giving up 21.4 points per contest, ranking this team at 13th in the NFL. They have granted 5 touchdowns through the air and 190.6 pass yds per outing, giving them a rank of 7th in football. Kansas City has yielded a total of 617 rushing yds (123.4 yds per outing), and 6 touchdowns via the rush this season. The Chiefs defense has participated in 288 plays from the line of scrimmage, putting them 9th in the league. The defense has recorded 6 turnovers (2 fumbles forced and 4 interceptions) so far this season. Altogether, they have conceded 107 points in total.

Who will win tonight's Lions-Chiefs NFL game against the spread?

Tony's Pick: Take the Lions -1

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