Detroit Lions vs Los Angeles Rams Prediction, 12/14/2025 NFL Picks, Best Bets & Odds Week 15
Game: Detroit Lions vs Los Angeles Rams
Date: Sunday, December 14, 2025
Location: SoFi Stadium in Inglewood, CA
TV: FOX
Odds-Point Spread: Rams (-5.5)
Total-Over-Under: 55.5
The Detroit Lions (8-5) are headed to SoFi Stadium on Sunday where they will compete against the Los Angeles Rams (10-3). Detroit opens as 5.5-point underdogs from Vegas oddsmakers. The total is set at 55.5.
The Detroit Lions head into this game 8-5 on the season. The last time they stepped on the gridiron, the Lions played against the Dallas Cowboys and notched a win by a score of 44-30. Jahmyr Gibbs was the best rusher for the Lions with 12 attempts for 43 yds (3.6 yards per carry). Jahmyr Gibbs held an average of 11.0 yds per catch by recording 77 yards on 7 catches. Jared Goff finished 25-34 with 309 yards through the air and 1 TD. He had a QB rating of 111 and ended the game without throwing an interception. Against the run, the Lions gave up 91 yards on 24 tries, which is an average of 3.8 yds per run surrendered. Detroit conceded 31 completions on 47 attempts for a total of 326 yards, and a completion rate of 66.0%. When all was said and done, they tallied 56 plays which totaled 408 yards. The Detroit Lions ended up running the ball 22 different times and tallied 109 yards, which is an average of 5.0 yds per attempt.

If you analyze scoring points, the NFC members average 30.3 points per outing. Collectively, they average 135.8 rushing yds putting them 5th in professional football. The Lions have accrued 4,923 yds on the year. Detroit has collected 159 1st downs, and they have been called for 82 penalties for 593 yards. They have given the ball to the opposition 8 times (5 picks and 3 fumbles lost). Regarding scoring touchdowns, Detroit has earned 27 touchdowns through the air and 20 TD's on the ground.
Concerning yards via the pass, the Lions have surrendered 2,876 yards, giving them a rank of 19th in the league. They have allowed 221.2 yds per contest via the pass, and are conceding a completion percentage of 61.4%. All in all, they have allowed 1,335 yards on the ground through 13 matchups on the year. They have surrendered 26 touchdowns by way of the pass, plus 9 touchdowns by way of the ground game. All in all, they are granting 323.9 yds per contest, giving them a rank of 15th in pro football. They are allowing an average of 3.9 yds per run and 102.7 rushing yds per contest on the year. The Lions currently rank 18th in professional football when analyzing their defensive abilities, conceding 23.4 points per contest.
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The Rams head into this matchup 10-3 for this campaign. When they last took the field, the Rams went home victorious with a score of 45-17 against the Arizona Cardinals. Matthew Stafford (3 touchdowns) ended the game with 281 yards on 22-31 through the air while his QB rate was 131.2. He didn't toss any interceptions and his avg yards per attempt was 9.1 yds. Kyren Williams carried the football 13 times for 84 yards, walking away from the game with 6.5 yds per carry for Los Angeles. Puka Nacua was the leading receiver for the Rams, hauling in 7 passes for 167 yds (23.9 yards per reception). Los Angeles rushed for 6.9 yards per tote, finishing with a total of 249 yds on 36 carries. The Rams finished the contest with 530 yds while running 67 plays (7.9 yards per play). The Rams pass defense allowed a completion rate of 56.8%, relinquishing 263 yards on 25 for 44 passing. Los Angeles surrendered 14 rush attempts for 51 yds (3.6 yards per rush).
In terms of their ability to score points, the Rams currently rank 4th in professional football, with 29.2 points per contest. In this season, the Rams have thrown for 3,240 yards via the pass and average 249.2 yards via the pass per game, giving them a rank of 3rd in the league. They average 123.9 rushing yards per contest, and have rushed for 1,611 yards. The Los Angeles Rams have an average of 373.2 total yards per outing, putting them 4th in professional football. The Los Angeles offense has relinquished 456 yds on 57 infractions, giving them a rank of 32nd in pro football if you're looking at hurting your team. They have compiled 4 INTs while granting 7 lost fumbles, and have been able to tally 173 1st downs as a unit.
The Rams are giving up 17.5 PPG, which ranks them 3rd in the NFL. They have relinquished 18 touchdowns through the air as well as 211.5 yards through the air per game, which has them ranked 16th in professional football. Los Angeles has yielded a total of 1,345 rushing yards (103.5 yds per game), as well as 4 touchdowns to runners on the season. The Rams defense has participated in 841 plays, giving them a rank of 28th in the league. The defense has collected 21 takeaways (8 fumbles forced and 13 INTs) this season. On the whole, they have conceded 227 points.
Who will win tonight's Lions-Rams NFL game against the spread?
Guy's Pick: Take the Lions +5.5
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Additional Resources:
Los Angeles Rams - Twitter
Detroit Lions - Twitter

