Detroit Lions vs Minnesota Vikings Prediction, 12/25/2025 NFL Picks, Best Bets & Odds Week 16
Game: Detroit Lions vs Minnesota Vikings
Date: Thursday, December 25, 2025
Location: U.S. Bank Stadium in Minneapolis, MN
TV: Netflix
Odds-Point Spread: Vikings (+7.5)
Total-Over-Under: 43
U.S. Bank Stadium is the location where the Minnesota Vikings (7-8) will take on the Detroit Lions (8-7) on Thursday. Minnesota opens as 7.5-point underdogs from oddsmakers. The over-under has been set at 43.
The Detroit Lions come into this game holding a record of 8-7 this season. In their last contest, the Lions took the field against the Pittsburgh Steelers and took a loss by a final of 29-24. Jahmyr Gibbs was the leader on the ground for the Lions with 7 attempts for 2 yds (0.3 yards per carry). Jahmyr Gibbs averaged 6.6 yds per reception by recording 66 yards on 10 catches. Jared Goff went 34-54 with 364 yards passing and 3 touchdowns. He had a QB rate of 101.2 and finished the contest with no picks. Against the rush, the Lions conceded 230 yards on 27 tries, which is 8.5 yds per run allowed. Detroit surrendered 27 pass completions on 41 tries for a total of 251 yds, and a completion percentage of 65.9%. Overall, they tallied 66 plays which totaled 361 yards. The Detroit Lions ended up running the ball 12 different times and amassed 15 yds, which had them averaging 1.3 yards per tote.

The Lions currently have 5,680 yards on the year. Detroit has attained 195 first downs offensively, and they have been called for 93 penalties for 658 yds. When you look at getting the ball into the endzone, Detroit has compiled 33 passing TD's and 21 TD's via the ground game. They have given the ball to the opposition 8 times (5 interceptions and 3 fumbles). Collectively, they're averaging 123.4 running yards which has them sitting 12th in football. When you look at getting the ball into the endzone, the NFC North members hold an average of 30.1 points per game.
The Lions are ranking 23rd in the league regarding the other team scoring points, conceding 24.9 points per contest. They are allowing teams to run for an average of 4.3 yards per rush and 114.9 rushing yards per game for this campaign. When examining yards via the pass, the Lions have relinquished 3,487 yds, which has them ranking 25th in professional football. They have given up 232.5 yards per game through the air, and are conceding a completion rate of 61.9%. Altogether, they are yielding 347.4 yards per game, which is good for 23rd in football. They have surrendered 29 touchdowns by way of the pass, along with 14 touchdowns to rushers. Altogether, they have granted 1,724 rushing yards through 15 matchups this season.
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The Vikings come into this game with a record of 7-8 over the course of this year. When they last took the field, the Vikings got the win with a final of 16-13 against the New York Giants. J.J. McCarthy ended the contest with 108 yards on 9-14 through the air while his quarterback rate was 58. He had 1 interception and his avg yards per attempt was 7.7 yds. Aaron Jones carried the rock 21 times for 85 yards, ending the contest with 4.0 yds per carry for Minnesota. Justin Jefferson was featured in the passing game for the Vikings, catching 6 footballs for 85 yards (14.2 yds per reception). Minnesota rushed the ball for 3.7 yards per attempt, finishing with a total of 114 yards on 31 attempts. The Vikings finished with a total of 240 yds while running 54 plays (4.4 yards per play). The Vikings secondary gave up a completion rate of 53.8%, relinquishing 13 yds on 7 for 13 through the air. Minnesota relinquished 30 rushing attempts for 128 yds (4.3 yds per carry).
The Minnesota Vikings maintain an average of 276.7 yards per contest, which is good for 28th in the NFL. They average 103.1 rushing yds per game, and have carried the ball for 1,546 yards. They have allowed 21 picks while allowing 8 fumbles lost, and have been able to earn 141 1st downs as an offense. The Minnesota offense has yielded 846 yards on 106 penalties, which is 8th in pro football with reference to helping out the other team. In this campaign, the Vikings have a total of 2,605 yards through the air and are sitting at 173.7 yards through the air per game, which has them ranking 28th in the league. When examining their ability to score points, the Vikings are ranked 26th in football, by tallying 20.3 points per game.
The Vikings are allowing 21.3 points per game, which has them ranking 12th in professional football. They have surrendered 14 touchdowns by way of the pass along with 169.2 passing yards per contest, which is good for 3rd in the NFL. Minnesota has yielded a total of 1,914 running yds (127.6 yards per game), as well as 13 touchdowns by way of the ground game over the course of this year. The Vikings defense has been on the field for 911 plays from the line of scrimmage, which ranks 13th in pro football. Their defense has attained 15 takeaways (9 fumbles forced and 6 picks) on the campaign. Overall, they have allowed 320 pts.
Who will win tonight's Lions-Vikings NFL game against the spread?
Guy's Pick: Take the Vikings +7.5
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Additional Resources:
Minnesota Vikings - Twitter
Detroit Lions - Twitter

