Los Angeles Rams vs Arizona Cardinals Prediction, 12/7/2025 NFL Picks, Best Bets & Odds Week 14

Game: Los Angeles Rams vs Arizona Cardinals

Date: Sunday, December 7, 2025

Location: State Farm Stadium in Glendale, AZ

TV: FOX

Odds-Point Spread: Cardinals (+8)

Total-Over-Under: 48.5

The Los Angeles Rams (9-3) are traveling to State Farm Stadium on Sunday where they will play the Arizona Cardinals (3-9). Los Angeles opens as 8-point favorites from oddsmakers. The over-under comes in at 48.5.

The Los Angeles Rams step on the gridiron holding a record of 9-3 for the season. The last time they stepped on the gridiron, the Rams took on the Carolina Panthers and took a loss by a score of 31-28. Blake Corum was the rushing leader for the Rams with 7 totes for 81 yards (11.6 yds per attempt). Xavier Smith had an average of 27.3 yards per catch by recording 82 yards on 3 catches. Matthew Stafford finished 18-28 with 243 yards through the air and 2 touchdowns. He had a quarterback rate of 85.9 and finished the game with 2 interceptions. When it came to stopping the run, the Rams conceded 164 yards on 40 tries, which is 4.1 yds per run surrendered. Los Angeles conceded 15 completions on 20 attempts for 194 yds, and a completion percentage of 75.0%. Overall, they tallied 49 plays which gave them 379 yards. The Los Angeles Rams ended up rushing 21 different times and totaled 152 yards, which earned them an average of 7.2 yds per attempt.

The Rams have accrued 4,321 total yards for the season. Los Angeles has tallied 160 first downs as a unit, and they have committed 52 infractions for 426 total yards. If you're looking at putting points on the board, Los Angeles has notched 32 passing TD's and 10 touchdowns via the ground. They have given the ball away 11 times (4 interceptions and 7 lost fumbles). As a team, they have an average of 113.5 rushing yards which is 19th in professional football. If you look at getting the ball in the endzone, the Rams hold an average of 27.8 points per game.

Concerning yards via the pass, the Rams have allowed 2,487 yds, which has them ranked 13th in the NFL. They have surrendered 207.3 total yards per contest by way of the pass, and are surrendering a completion rate of 64.4%. Overall, they have allowed 1,294 yards via the ground game in 12 matchups over the course of this year. They have conceded 16 touchdowns through the air, in addition to 4 touchdowns to rushers. Overall, they are yielding 315.1 yds per outing, which is 13th in professional football. Opposing teams are running for an average of 3.9 yards per run and 107.8 rushing yards per outing this year. The Rams are ranking 2nd in pro football when examining the other team scoring points, yielding 17.5 points per outing.

Get all of our NFL Picks Today

The Cardinals head into this matchup 3-9 for the season. The last time they took the field, the Cardinals walked away with a loss by a score of 20-17 when they faced the Tampa Bay Buccaneers. Jacoby Brissett (2 touchdowns) finished the game with 301 yds on 29-40 through the air while his QB rating was 100.1. He threw 1 pick and his avg yards per attempt was 7.5 yds. Zonovan Knight carried the ball 11 times for 62 yards, walking away from the game with 5.6 yards per carry for Arizona. Trey McBride was the best receiver for the Cardinals, snagging 8 throws for 82 yards (10.3 yards per reception). Arizona ran for 5.0 yards per attempt, totaling 95 yards on 19 attempts. The Cardinals finished the contest with 386 yds while running 59 plays (6.5 yards per play). The Cardinals pass defense allowed a completion percentage of 64.3%, relinquishing 184 yards on 18 for 28 through the air. Arizona gave up 27 run attempts for 95 yards (3.5 yds per rush).

When talking about their scoring prowess, the Cardinals are ranking 20th in the NFL, by scoring 22.1 points per outing. For the season, the Cardinals have compiled 2,840 passing yds and are averaging 236.7 passing yds per game, which ranks them 8th in pro football. They maintain an average of 100.6 running yds per outing, and have rushed for 1,207 yards. The Arizona Cardinals maintain an average of 337.3 total yards per game, which has them ranked 16th in pro football. The Arizona offense has allowed 656 yards by way of 89 violations, which has them ranking 8th in the NFL when you look at giving up free yards. They have thrown 7 picks while granting 8 fumbles lost, and have been able to tally 156 first downs offensively.

The Cardinals are yielding 25.3 points per contest, which is 24th in professional football. They have surrendered 17 touchdowns by way of the pass and 219.6 passing yards per contest, ranking this team at 21st in pro football. Arizona has relinquished a total of 1,351 rushing yards (112.6 yards per game), and 12 touchdowns on the ground for the season. The Cardinals defense has participated in 742 plays from scrimmage, which is 15th in the NFL. The D has racked up 17 takeaways (8 fumbles forced and 9 interceptions) for the season. All in all, they have conceded 303 pts.

Who will win tonight's Rams-Cardinals NFL game against the spread?

Josh's Pick: Take the Cardinals +8

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get NFL picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.