Los Angeles Rams vs Carolina Panthers Prediction, 11/30/2025 NFL Picks, Best Bets & Odds Week 13

Game: Los Angeles Rams vs Carolina Panthers

Date: Sunday, November 30, 2025

Location: Bank of America Stadium in Charlotte, NC

TV: FOX

Odds-Point Spread: Panthers (+10)

Total-Over-Under: 45

The Carolina Panthers (6-6) welcome the Los Angeles Rams (9-2) at Bank of America Stadium on Sunday. Carolina is 10-point dogs. The over-under has been set at 45.

The Los Angeles Rams head into this matchup 9-2 for the year. The last time they stepped on the gridiron, the Rams went up against the Tampa Bay Buccaneers and notched a win by a score of 34-7. Matthew Stafford connected on 25-35 with 273 yds passing and 3 TDs. He had a QB rate of 122.7 and ended the contest with no interceptions. Kyren Williams was the rushing leader for the Rams with 12 totes for 46 yards (3.8 yds per carry). Puka Nacua had an average of 13.9 yds per catch by earning 97 yards on 7 catches. The Los Angeles Rams ran the rock 19 different times and totaled 70 yards, which is an average of 3.7 yards per carry. In all, they tallied 54 plays which gave them 333 yards. Los Angeles relinquished 17 completions on 34 attempts for a total of 70 yards, and a completion rate of 50.0%. When it came to stopping the run, the Rams conceded 123 yds on 29 tries, which is an average of 4.2 yds per run surrendered.

The Rams have attained 3,942 yds for this campaign. Los Angeles has a total of 148 first downs offensively, and they have been called for 51 infractions for 421 yds. When examining notching touchdowns, Los Angeles has recorded 30 passing touchdowns and 8 touchdowns via the run. They have surrendered the ball 8 different times (2 INTs and 6 lost fumbles). As a unit, they maintain an average of 110.0 rushing yds which has them sitting 22nd in the league. If you're looking at scoring points, the NFC West members average 27.8 points per game.

The Rams sit 1st in football when you look at team defense, granting 16.3 points per contest. The opposition is running for an average of 3.9 yards per tote and 102.7 running yards per game for the year. If you're looking at yards through the air, the Rams have conceded 2,293 yds, which is 13th in the league. They have relinquished 208.5 yds per contest by way of the pass, and are conceding a completion% of 63.8%. Altogether, they are allowing 311.2 yds per game, which has them sitting 9th in the league. They have relinquished 13 touchdowns by way of the pass, plus 4 touchdowns by way of the ground game. All in all, they have granted 1,130 yards on the ground through 11 outings on the year.

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The Panthers step on the gridiron with a record of 6-6 this season. The last time they stepped on the gridiron, the Panthers took a loss by a score of 20-9 when they played the San Francisco 49ers. Bryce Young (1 touchdown) ended the contest with 169 yds on 18-29 passing while his QB rating was 60.8. He tossed 2 picks and his avg yards per attempt was 5.8 yds. Rico Dowdle carried the ball 6 times for 38 yds, ending the game with 6.3 yards per carry for Carolina. Rico Dowdle had the best day in terms of receiving for the Panthers, hauling in 4 throws for 36 yds (9.0 yds per reception). Carolina rushed for 5.3 yds per attempt, finishing the contest with 69 yds on 13 carries. The Panthers finished with 230 yards on 42 plays (5.5 yds per play). The Panthers secondary gave up a completion rate of 71.9%, surrendering 193 yds on 23 for 32 passing. Carolina allowed 38 rush attempts for 147 yds (3.9 yds per rush).

The Carolina Panthers average 307.3 total yards per contest, which is good for 22nd in professional football. They average 122.3 rush yds per contest, and have carried the ball for 1,467 total yards. They have thrown 10 interceptions while yielding 7 fumbles lost, and have tallied 130 1st downs as an offense. The Carolina offense has conceded 493 total yards on 64 penalties, which ranks 28th in the league when you look at giving up free yards. For the year, the Panthers have a total of 2,220 yards via the pass and have an average of 185.0 yards via the pass per contest, which is 27th in pro football. When you look at how much they score, the Panthers are ranking 28th in professional football, by scoring 18.0 points per game.

The Panthers are relinquishing 22.4 points per outing, which has them sitting 14th in the NFL. They have relinquished 14 touchdowns by way of the pass plus 211.2 pass yds per contest, which has them sitting 16th in the NFL. Carolina has granted a total of 1,391 running yards (115.9 yds per game), as well as 14 touchdowns by way of the ground game for the year. The Panthers defense has participated in 709 plays from the line of scrimmage, which has them sitting 25th in football. The defense has a total of 14 takeaways (4 forced fumbles and 10 picks) for this campaign. In total, they have relinquished 269 points in total.

Who will win tonight's Rams-Panthers NFL game against the spread?

Guy's Pick: Take the Rams -10

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