Miami Dolphins vs Carolina Panthers Prediction, 10/5/2025 NFL Picks, Best Bets & Odds Week 5
Game: Miami Dolphins vs Carolina Panthers
Date: Sunday, October 5, 2025
Location: Bank of America Stadium in Charlotte, NC
TV: FOX
Odds-Point Spread: Panthers (-1)
Total-Over-Under: 44.5
The Carolina Panthers (1-3) will try to defeat the Miami Dolphins (1-3) at Bank of America Stadium on Sunday. Carolina is 1-point favorites from oddsmakers. The betting total is set at 44.5.
The Miami Dolphins step onto the field holding a record of 1-3 on the season. When they last took the field, the Dolphins played against the New York Jets and walked away with a win by a score of 27-21. Tua Tagovailoa went 17-25 with 177 yds through the air and 2 touchdowns. He had a QB rating of 114.9 and finished the contest with no interceptions. Tyreek Hill had an average of 11.2 yards per catch by recording 67 yards on 6 receptions. De'Von Achane was the leader on the ground for the Dolphins with 20 attempts for 99 yds (5.0 yds per attempt). When all was said and done, they ran 56 plays which gave them a total of 300 yards. The Miami Dolphins ran the ball a total of 31 different times and tallied 123 yards, which is an average of 4.0 yds per attempt. On the ground, the Dolphins conceded 197 yards on 28 attempts, which averages out to 7.0 yds per rush allowed. Miami surrendered 20 completions on 27 attempts for 207 yards, and a completion percentage of 74.1%.

The Dolphins have earned 1,145 total yards for the season. Miami has tallied 47 first downs as a team, and they have been hurt by 25 infractions for 177 total yards. If you're looking at scoring points, Miami has amassed 7 touchdowns through the air and 2 rushing touchdowns. They have turned the ball over 5 different times (4 interceptions and 1 fumble). Collectively, they average 98.0 rushing yds which is 27th in football. In terms of scoring, the AFC representatives are sitting at 20.8 points per outing.
Regarding yards through the air, the Dolphins have conceded 883 total yards, putting them 20th in the league. They have given up 220.8 yds per contest through the air, and are yielding a completion rate of 77.6%. Overall, they have allowed 632 running yards through 4 matchups on the year. They have conceded 7 touchdowns through the air, as well as 5 touchdowns on the ground. In total, they are allowing 378.8 total yards per game, putting them 26th in the NFL. Opposing teams are running for an average of 5.1 yds per attempt on the ground and 158.0 rushing yards per contest on the year. The Dolphins are sitting 26th in professional football when examining opponents scoring, conceding 29.5 points per game.
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The Panthers step onto the field with a record of 1-3 for this campaign. The last time they stepped on the gridiron, the Panthers walked away with a loss by a score of 42-13 when they faced the New England Patriots. Bryce Young (1 TD) ended the contest with 150 yards on 18-30 through the air while his QB rate was 84. He didn't toss any picks and his average yards per pass attempt was 5.0 yards. Chuba Hubbard ran the football 10 times for 49 yards, ending the contest with 4.9 yds per carry for Carolina. Tommy Tremble was a featured target for the Panthers, catching 5 passes for 42 yards (8.4 yds per catch). Carolina ran the ball for 4.6 yds per carry, finishing the game with 129 yds on 28 carries. The Panthers finished the game with 326 yards on 64 plays (5.1 yards per play). The Panthers passing defense allowed a completion percentage of 77.8%, surrendering 203 yards on 14 for 18 passing. Carolina relinquished 29 rush attempts for 104 yards (3.6 yds per rush).
The Carolina Panthers maintain an average of 289.3 total yards per game, which is 24th in football. They maintain an average of 100.3 rushing yards per outing, and have toted the ball for 401 total yards. They have thrown 3 interceptions while granting 3 fumbles lost, and have recorded 45 1st downs as a unit. The Carolina offense has surrendered 202 total yards by way of 22 penalty flags, which is good for 29th in professional football regarding helping out the other team. On the year, the Panthers have thrown for a total of 756 yards through the air and hold an average of 189.0 yards through the air per contest, putting them 21st in the league. If you analyze the points being put on the board, the Panthers rank 26th in football, maintaining an average of 18.8 PPG.
The Panthers are relinquishing 23.8 points per contest, which has them ranked 19th in the NFL. They have conceded 4 touchdowns via the pass in addition to 198.3 passing yds per outing, which is 12th in football. Carolina has surrendered a total of 517 rushing yds (129.3 total yards per game), in addition to 5 touchdowns via the rush for the year. The Panthers defense has taken the field for 225 plays from scrimmage, putting them 4th in football. Their defense currently has 5 takeaways (1 fumble and 4 picks) on the season. On the whole, they have conceded 95 points.
Who will win tonight's Dolphins-Panthers NFL game against the spread?
Tony's Pick: Take the Dolphins +1
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Additional Resources:
Carolina Panthers - Twitter
Miami Dolphins - Twitter