New Orleans Saints vs Tennessee Titans Prediction, 12/28/2025 NFL Picks, Best Bets & Odds Week 17

Game: New Orleans Saints vs Tennessee Titans

Date: Sunday, December 28, 2025

Location: Nissan Stadium in Nashville, TN

TV: CBS

Odds-Point Spread: Titans (+2.5)

Total-Over-Under: 39.5

Nissan Stadium is the site where the Tennessee Titans (3-12) will attempt to defeat the New Orleans Saints (5-10) on Sunday. Tennessee opens as 2.5-point underdogs from oddsmakers. The betting total comes in at 39.5.

The New Orleans Saints step on the gridiron holding a record of 5-10 on the year. In their last game, the Saints faced the New York Jets and walked away with a win by a score of 29-6. Tyler Shough finished 32-49 with 308 yards passing and 1 TD. He had a quarterback rating of 89.5 and finished the contest without throwing an interception. Taysom Hill was the rushing leader for the Saints with 12 attempts for 42 yds (3.5 yds per attempt). Chris Olave had an average of 14.8 yds per catch by notching 148 yds on 10 receptions. The New Orleans Saints ended up running the ball 25 different times and accrued 84 yds, which had them averaging 3.4 yds per attempt. Once the final whistle blew, they ran 75 plays which totaled 412 yds. New Orleans gave up 22 completions on 35 attempts for 131 yds, and a completion percentage of 62.9%. Against the rush, the Saints conceded 64 yards on 20 tries, which averages out to 3.2 yds per run allowed.

With reference to scoring points, the New Orleans Saints are sitting at 17.0 points per outing. Collectively, they hold an average of 92.8 rushing yds which has them ranked 30th in the league. The Saints currently have 4,568 yards on the campaign. New Orleans has earned 162 1st downs as an offense, and they have committed 106 infractions for 796 yds. They have given the ball to the opposition 21 times (11 INTs and 10 lost fumbles). When it comes to scoring, New Orleans currently has 16 passing touchdowns and 7 TD's via the ground game.

The Saints currently sit 14th in pro football with reference to team defense, allowing 22.5 points per contest. They are giving up 4.1 yards per run and 126.2 running yds per game over the course of this year. When it comes to pass yds, the Saints have conceded 2,659 yards, which is 5th in pro football. They have yielded 177.3 yds per outing by way of the pass, and are granting a completion rate of 65.2%. Altogether, they are granting 303.5 total yards per game, which has them ranking 9th in the league. They have conceded 22 touchdowns via the pass, as well as 12 touchdowns by way of the ground game. Altogether, they have yielded 1,893 yards on the ground through 15 outings for this campaign.

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The Titans come into this game with a record of 3-12 this season. The last time they stepped on the gridiron, the Titans went home victorious with a score of 26-9 against the Kansas City Chiefs. Tony Pollard carried the ball 21 times for 102 yds, walking away from the contest with 4.9 yards per carry for Tennessee. Chigoziem Okonkwo was the top contributor in the passing game for the Titans, bringing in 6 footballs for 44 yards (7.3 yards per reception). Cam Ward (2 TDs) finished the contest with 228 yds on 21-28 through the air while his quarterback rate was 122.3. He didn't throw any picks and his avg yards per attempt was 8.1 yds. Tennessee conceded 15 rushing attempts for 51 yds (3.4 yards per rush). The Titans pass defense conceded a completion rate of 58.3%, surrendering 82 yards on 14 for 24 passing. The Titans finished the game with a total of 376 yards while running 68 plays (5.5 yds per play). Tennessee ran the ball for 4.1 yards per attempt, finishing with a total of 164 yards on 40 carries.

When examining the points being put on the board, the Titans are ranked 30th in professional football, scoring 16.7 points per game. In this campaign, the Titans have a total of 2,479 yards through the air and are sitting at 165.3 yards through the air per game, which has them ranking 31st in the league. They average 93.6 rush yds per outing, and have rushed for 1,404 yds. The Tennessee Titans average 258.9 yards per game, which has them ranked 31st in the league. The Tennessee offense has allowed 909 yards by way of 120 penalties, which has them sitting 1st in football if you examine giving up free yards. They have tossed 7 interceptions while yielding 10 fumbles lost, and have been able to tally 139 first downs as a unit.

They have relinquished 25 touchdowns by way of the pass as well as 222.9 yards via the pass per contest, which has them ranking 21st in professional football. Tennessee has yielded a total of 1,781 rushing yards (118.7 yards per contest), plus 19 touchdowns to rushers this season. The defense has produced 13 turnovers (7 forced fumbles and 6 interceptions) for this campaign. In total, they have allowed 403 total points. The Titans defense has been on the field for 899 plays from the line of scrimmage, which has them ranking 11th in the league. The Titans are granting 26.9 points per contest, which has them ranking 26th in the league.

Who will win tonight's Saints-Titans NFL game against the spread?

Guy's Pick: Take the Saints -2.5

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