New York Giants vs New Orleans Saints Prediction, 10/5/2025 NFL Picks, Best Bets & Odds Week 5

Game: New York Giants vs New Orleans Saints

Date: Sunday, October 5, 2025

Location: Caesars Superdome in New Orleans, LA

TV: CBS

Odds-Point Spread: Saints (-1.5)

Total-Over-Under: 40.5

Caesars Superdome is where the New Orleans Saints (0-4) will try to defeat the New York Giants (1-3) on Sunday. New Orleans opens this matchup as 1.5-point favorites from oddsmakers. The total comes in at 40.5.

The New York Giants come into this game holding a record of 1-3 for this campaign. When they last stepped on the football field, the Giants faced the Los Angeles Chargers and earned the victory with a final of 21-18. Jaxson Dart went 13-20 with 111 yards passing and 1 touchdown. He had a QB rating of 96 and ended the contest without throwing an interception. Cam Skattebo was the leader on the ground for the Giants with 25 carries for 79 yards (3.2 yards per carry). Theo Johnson left with an average of 5.7 yds per catch by earning 17 yards on 3 receptions. The New York Giants ran the rock 42 times and accounted for 161 yds, which came out to an average of 3.8 yds per carry. When all was said and done, they had 63 plays which totaled 250 yds. New York surrendered 23 pass completions on 41 tries for a total of 186 yds, and a completion percentage of 56.1%. In the running game, the Giants gave up 152 yds on 13 attempts, which calculates to 11.7 yards per rush surrendered.

The Giants have tallied 1,268 total yards on the season. New York currently has 37 1st downs as a unit, and they have been flagged for 35 penalties for 320 yds. If you're looking at scoring points, New York has amassed 4 touchdowns through the air and 3 rushing touchdowns. They have coughed up the ball 3 times. Collectively, they average 112.3 rushing yds which is 17th in football. When you look at putting the ball in the endzone, the New York Giants hold an average of 18.3 points per contest.

The Giants are sitting 23rd in football when it comes to their defensive abilities, granting 25.3 points per outing. The opposition is running for 6.1 yds per running attempt and 153.0 rushing yds per game on the season. In terms of pass yds, the Giants have granted 942 yds, which ranks them 25th in pro football. They have conceded 235.5 yards per outing via the pass, and are giving up a completion rate of 63.8%. Overall, they are relinquishing 388.5 yds per contest, which has them ranked 29th in the NFL. They have surrendered 5 touchdowns via the pass, in addition to 6 touchdowns via the rush. On the whole, they have conceded 612 yards on the ground through 4 outings for this campaign.

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The Saints head into this matchup 0-4 on the season. In their last game, the Saints walked away with a loss by a score of 31-19 against the Buffalo Bills. Spencer Rattler (1 TD) finished the game with 126 yards on 18-27 through the air while his quarterback rating was 89.4. He didn't toss any picks and his average yards per pass attempt was 4.7 yards. Alvin Kamara carried the ball 15 times for 70 yds, ending the game with 4.7 yards per carry for New Orleans. Alvin Kamara was the best receiver for the Saints, grabbing 4 passes for 2 yards (0.5 yds per catch). New Orleans ran the ball for 5.6 yds per carry, finishing the contest with 189 yards on 34 carries. The Saints finished the game with a total of 298 yds while running 62 plays (4.8 yards per play). The Saints secondary gave up a completion rate of 72.7%, surrendering 191 yards on 16 for 22 passing. New Orleans conceded 32 rush attempts for 165 yards (5.2 yards per carry).

In terms of their scoring prowess, the Saints rank 28th in pro football, by tallying 16.5 points per outing. On the year, the Saints have thrown for a total of 708 yards through the air and hold an average of 177.0 yards through the air per contest, putting them 27th in the league. They hold an average of 124.0 rushing yards per contest, and have run for 496 total yards. The New Orleans Saints maintain an average of 301.0 total yards per outing, which has them ranked 22nd in pro football. The New Orleans offense has relinquished 252 total yards by way of 35 violations, putting them 5th in the league when you look at helping out the other team. They have allowed 2 interceptions while yielding 1 fumble, and have recorded 43 first downs as an offense.

They have surrendered 9 touchdowns via the pass in addition to 205.3 passing yds per game, which is good for 15th in professional football. New Orleans has conceded a total of 475 rushing yards (118.8 yds per contest), along with 4 touchdowns by way of the ground game on the season. The D currently has 3 takeaways (2 forced fumbles and 1 interception) for the year. All in all, they have granted 121 pts. The Saints defense has participated in 240 plays, putting them 15th in the league. The Saints are relinquishing 30.3 points per game, which is good for 30th in professional football.

Who will win tonight's Giants-Saints NFL game against the spread?

Parlays Pundit's Pick: Take the Saints -1.5 and over 40.5 total points

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