New York Jets vs New Orleans Saints Prediction, 12/21/2025 NFL Picks, Best Bets & Odds Week 16
Game: New York Jets vs New Orleans Saints
Date: Sunday, December 21, 2025
Location: Caesars Superdome in New Orleans, LA
TV: CBS
Odds-Point Spread: Saints (-4.5)
Total-Over-Under: 40.5
The New York Jets (3-11) are on their way to Caesars Superdome on Sunday where they will go up against the New Orleans Saints (4-10). New York opens as 4.5-point underdogs. The over-under has been set at 40.5.
The New York Jets step on the gridiron 3-11 on the campaign. In their last game, the Jets faced the Jacksonville Jaguars and took a loss by a score of 48-20. Isaiah Davis was the best rusher for the Jets with 9 carries for 58 yards (6.4 yards per carry). Adonai Mitchell held an average of 9.7 yards per catch by tallying 58 yds on 6 receptions. Brady Cook connected on 22-33 with 176 yds passing and 1 touchdown. He had a quarterback rating of 52.1 and walked away from the game with 3 interceptions. Against the rush, the Jets conceded 108 yds on 27 tries, which is 4.0 yards per run surrendered. New York relinquished 20 pass completions on 32 tries for a total of 330 yards, and a completion percentage of 62.5%. At the end of the game, they tallied 65 plays which gave them a total of 284 yards. The New York Jets rushed the ball a total of 32 times and accumulated 130 yds, which earned them an average of 4.1 yards per tote.

If you're looking at getting the ball in the endzone, the AFC members are averaging 19.7 PPG. Collectively, they're maintaining an average of 128.5 running yds giving them a rank of 7th in football. The Jets have notched 3,857 yards on the campaign. New York has recorded 119 first downs offensively, and they have been called for 94 infractions for 775 total yards. They have surrendered the ball 20 times (11 interceptions and 9 lost fumbles). When it comes to scoring touchdowns, New York has attained 14 passing touchdowns and 10 touchdowns via the ground.
When it comes to passing yds, the Jets have allowed 2,802 total yards, which ranks 12th in the league. They have surrendered 200.1 total yards per game by way of the pass, and are conceding a completion% of 63.0%. Altogether, they have given up 1,921 yards on the ground through 14 outings on the year. They have relinquished 25 touchdowns via the pass, along with 18 touchdowns via the rush. Altogether, they are relinquishing 337.4 total yards per contest, giving them a rank of 20th in football. The opposition is running for 4.4 yds per rushing attempt and 137.2 rush yards per contest this year. The Jets are 30th in pro football regarding the other team scoring points, relinquishing 28.4 points per outing.
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The Saints step on the gridiron with a record of 4-10 on the year. In their last game, the Saints got the victory with a final of 20-17 against the Carolina Panthers. Tyler Shough (1 touchdown) ended the game with 272 yards on 24-32 passing while his QB rating was 110.4. He didn't toss any interceptions and his Y-A was 8.5 yds. Tyler Shough carried the rock 8 times for 32 yds, finishing the game with 4.0 yards per attempt for New Orleans. Chris Olave was one of the featured targets for the Saints, catching 6 passes for 85 yds (14.2 yds per catch). New Orleans rushed for 3.2 yards per attempt, finishing the contest with 81 yds on 25 carries. The Saints finished with 337 yds while they ran 58 plays (5.8 yards per play). The Saints passing defense gave up a completion percentage of 62.5%, relinquishing 154 yds on 15 out of 24 passing. New Orleans gave up 31 rushing attempts for 127 yds (4.1 yards per rush).
The New Orleans Saints maintain an average of 296.9 yards per contest, which has them ranked 26th in professional football. They have an average of 93.4 running yds per contest, and have carried the ball for 1,308 total yards. They have compiled 11 interceptions while allowing 9 fumbles lost, and have been able to record 145 1st downs as a team. The New Orleans offense has relinquished 766 total yards on 103 penalty flags, which ranks 5th in the league if you're looking at making mistakes. For the season, the Saints have thrown for a total of 2,848 yards via the pass and hold an average of 203.4 yards via the pass per contest, giving them a rank of 21st in football. Regarding their ability to score points, the Saints are ranked 29th in the NFL, by tallying 16.1 points per game.
The Saints are relinquishing 23.7 points per game, which ranks 19th in the league. They have given up 22 touchdowns through the air in addition to 180.6 yards through the air per game, ranking this team at 6th in pro football. New Orleans has granted a total of 1,829 running yds (130.6 total yards per contest), plus 12 touchdowns to rushers over the course of this year. The Saints defense has been on the field for 857 plays from scrimmage, which ranks 13th in the league. The defense currently has 16 takeaways (8 forced fumbles and 8 INTs) on the year. On the whole, they have relinquished 332 total points.
Who will win tonight's Jets-Saints NFL game against the spread?
Tony's Pick: Take the Jets +4.5
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Additional Resources:
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