Philadelphia Eagles vs Kansas City Chiefs Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
Game: Philadelphia Eagles vs Kansas City Chiefs
Date: Sunday, September 14, 2025
Location: GEHA Field at Arrowhead Stadium in Kansas City, MO
TV: FOX
Odds-Point Spread: Chiefs (+1)
Total-Over-Under: 47
The Kansas City Chiefs (0-1) will take on the Philadelphia Eagles (1-0) at GEHA Field at Arrowhead Stadium on Sunday. Philadelphia opens this game as 1-point favorites. The over-under comes in at 47.
The Philadelphia Eagles step on the gridiron 1-0 over the course of this season. The last time they stepped on the football field, the Eagles faced off with the Dallas Cowboys and earned the victory with a final of 24-20. Saquon Barkley was the best rusher for the Eagles with 18 carries for 60 yards (3.3 yds per carry). Dallas Goedert left with an average of 6.3 yds per reception by notching 44 yards on 7 receptions. Jalen Hurts went 19-23 with 152 yds through the air. He had a QB rating of 94.2 and ended the game without throwing an interception. Against the run, the Eagles gave up 119 yds on 22 tries, which is 5.4 yards per run allowed. Philadelphia surrendered 21 pass completions on 34 tries for 188 yds, and a completion percentage of 61.8%. For the game, they ran 61 plays which gave them a total of 302 yards. The Philadelphia Eagles ran the rock 38 times and accounted for 158 yards, which earned them an average of 4.2 yds per attempt.

The Eagles have accumulated 302 yards for the year. Philadelphia has compiled 6 1st downs as a team, and they have committed 9 infractions for 110 yards. If you're looking at scoring touchdowns, Philadelphia has compiled 0 passing TD's and 3 touchdowns on the ground. They have yet to turn the ball over. Offensively, they're sitting at 158.0 rushing yds putting them 5th in pro football. When talking about notching touchdowns, the Philadelphia Eagles are averaging 24.0 points per game.
The Eagles are sitting 17th in pro football if you're looking at their defensive prowess, yielding 20.0 points per game. The opposition is running for an average of 5.4 yards per attempt on the ground and 119.0 rush yds per outing over the course of this season. If you look at pass yards, the Eagles have surrendered 188 total yards, ranking them 14th in pro football. They are granting a completion% of 61.8%. On the whole, they are relinquishing 307.0 yards per contest, which is 16th in professional football. They have granted 2 touchdowns on the ground.
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The Chiefs come into this game with a record of 0-1 on the campaign. The last time they stepped on the gridiron, the Chiefs took a defeat with a final score of 27-21 when they played the Los Angeles Chargers. Patrick Mahomes (1 touchdown) finished the game with 258 yards on 24-39 passing while his QB rate was 89.5. He didn't toss any interceptions and his average yds per pass attempt was 6.6 yards. Patrick Mahomes ran the ball 6 times for 57 yds, finishing the game with 9.5 yds per carry for Kansas City. Marquise Brown was the top contributor in the passing game for the Chiefs, snagging 10 passes for 99 yds (9.9 yards per catch). Kansas City ran for 5.8 yards per attempt, finishing the game with 98 yards on 17 attempts. The Chiefs finished the game with a total of 347 yards while they ran 56 plays (6.2 yards per play). The Chiefs secondary allowed a completion percentage of 73.5%, relinquishing 304 yards on 25 out of 34 passing. Kansas City relinquished 25 attempts on the ground for 90 yards (3.6 yds per rush).
When examining the points being put on the board, the Chiefs currently sit 14th in the league, with an average of 21.0 points per game. For the season, the Chiefs sit at 249 yards through the air which has them sitting 9th in the league. They have toted the ball for 98 yards. The Kansas City Chiefs have an average of 347.0 yards per outing, which ranks 11th in professional football. The Kansas City offense has allowed 71 yards by way of 10 penalties, ranking them 7th in football when examining giving up free yards.
They have surrendered 3 touchdowns through the air in addition to 304.0 pass yards per game, ranking them 30th in pro football. Kansas City has relinquished a total of 90 rushing yards. Their defense has yet to take the ball away. The Chiefs defense has been on the field for 62 plays from the line of scrimmage, putting them 19th in the NFL. The Chiefs are relinquishing 27.0 points per game, which is 25th in professional football.
Who will win tonight's Eagles-Chiefs NFL game against the spread?
Tony's Pick: Take the Eagles -1
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Additional Resources:
Kansas City Chiefs - Twitter
Philadelphia Eagles - Twitter