Seattle Seahawks vs Carolina Panthers Prediction, 12/28/2025 NFL Picks, Best Bets & Odds Week 17
Game: Seattle Seahawks vs Carolina Panthers
Date: Sunday, December 28, 2025
Location: Bank of America Stadium in Charlotte, NC
TV: CBS
Odds-Point Spread: Panthers (+7)
Total-Over-Under: 42.5
The Seattle Seahawks (12-3) are hitting the road to Bank of America Stadium on Sunday where they will attempt to beat the Carolina Panthers (8-7). Seattle opens as 7-point favorites. The betting total is set at 42.5.
The Seattle Seahawks head into this matchup 12-3 over the course of this season. In their last contest, the Seahawks stepped onto the field against the Los Angeles Rams and took home the win by a score of 38-37. Sam Darnold went 22-34 with 270 yards passing and 2 touchdowns. He had a quarterback rating of 84.2 and ended the game with 2 interceptions. Jaxon Smith-Njigba had an average of 12.0 yards per catch by accounting for 96 yards on 8 receptions. Kenneth Walker III led the offense in rushing for the Seahawks with 11 totes for 100 yards (9.1 yds per attempt). When the final whistle blew, they ran 59 plays which totaled 415 yards. The Seattle Seahawks ended up running the ball 25 different times and accumulated 171 yds, which came out to an average of 6.8 yards per tote. In the running game, the Seahawks gave up 124 yards on 39 attempts, which averages out to 3.2 yards per rush surrendered. Seattle conceded 29 pass completions on 49 tries for 457 yards, and a completion percentage of 59.2%.

When you look at getting the ball into the endzone, the group residing in Seattle hold an average of 29.5 points per game. As a team, they're averaging 116.9 rushing yards which ranks 21st in pro football. The Seahawks have notched 5,324 yds on the campaign. Seattle has compiled 160 first downs, and they have been flagged for 91 penalties for 728 yards. They have given the ball to the opposition 26 different times (14 interceptions and 12 lost fumbles). In terms of scoring points, Seattle has racked up 24 touchdowns through the air and 16 touchdowns via the ground.
The Seahawks currently sit 2nd in pro football with reference to opponents scoring, yielding 18.6 points per contest. They are allowing teams to run for an average of 3.7 yards per rush and 94.1 rushing yards per game for this campaign. When examining yards via the pass, the Seahawks have relinquished 3,137 yds, which has them ranking 14th in professional football. They have given up 209.1 yards per game through the air, and are conceding a completion rate of 62.3%. In total, they are yielding 303.2 yards per game, which has them sitting 8th in football. They have granted 20 touchdowns by way of the pass, and 8 touchdowns to rushers. Altogether, they have allowed 1,411 running yards through 15 outings on the year.
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The Panthers head into this matchup 8-7 over the course of this season. In their last game, the Panthers got the victory with a final of 23-20 against the Tampa Bay Buccaneers. Bryce Young (2 TDs) finished the game with 191 yards on 21-32 through the air while his quarterback rating was 102.5. He didn't throw any interceptions and his avg yards per attempt was 6.0 yards. Tetairoa McMillan had the best day in terms of receiving for the Panthers, hauling in 6 passes for 73 yards (12.2 yards per catch). Rico Dowdle ran the football 9 times for 29 yards, finishing the contest with 3.2 yds per attempt for Carolina. The Panthers finished the game with 275 yards while running 52 plays (5.3 yds per play). Carolina rushed the ball for 5.1 yards per carry, finishing with 101 yds on 20 attempts. Carolina allowed 33 run attempts for 169 yards (5.1 yds per carry). The Panthers passing defense allowed a completion percentage of 69.2%, surrendering 127 yards on 18 out of 26 passing.
When examining the points being put on the board, the Panthers are ranked 27th in professional football, scoring 19.1 points per game. On the year, the Panthers have earned 2,742 pass yards and hold an average of 182.8 pass yards per outing, which has them sitting 26th in the league. They maintain an average of 123.9 rushing yds per contest, and have carried the football for 1,859 yards. The Carolina Panthers maintain an average of 306.7 yards per game, which is good for 25th in football. The Carolina offense has surrendered 696 yards by way of 87 penalty flags, which is good for 26th in football with reference to making mistakes. They have allowed 10 picks while allowing 8 fumbles, and have tallied 154 first downs offensively.
The Panthers are yielding 22.5 points per game, which is good for 13th in football. They have yielded 18 touchdowns by way of the pass and 209.6 pass yards per outing, which has them sitting 16th in the league. Carolina has yielded a total of 1,793 running yds (119.5 yards per game), as well as 18 touchdowns by way of the ground game over the course of this year. The Panthers defense has been on the field for 884 plays from the line of scrimmage, which has them ranking 6th in the league. The defense has produced 18 turnovers (5 forced fumbles and 13 interceptions) for this campaign. On the whole, they have relinquished 337 points.
Who will win tonight's Seahawks-Panthers NFL game against the spread?
Tony's Pick: Take the Panthers +7
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Additional Resources:
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