Seattle Seahawks vs Jacksonville Jaguars Prediction, 10/12/2025 NFL Picks, Best Bets & Odds Week 6
Game: Seattle Seahawks vs Jacksonville Jaguars
Date: Sunday, October 12, 2025
Location: EverBank Stadium in Jacksonville, FL
TV: FOX
Odds-Point Spread: Jaguars (-1.5)
Total-Over-Under: 46.5
The Seattle Seahawks (3-2) are en route to EverBank Stadium on Sunday where they will try to defeat the Jacksonville Jaguars (4-1). Seattle opens as 1.5-point underdogs from oddsmakers. The over-under has been set at 46.5.
The Seattle Seahawks head into this game 3-2 this season. In their last contest, the Seahawks went up against the Tampa Bay Buccaneers and took a loss by a score of 38-35. Sam Darnold connected on 28-34 with 341 yds passing and 4 touchdowns. He had a QB rating of 135.4 and ended the contest with 1 pick. Kenneth Walker III was the rushing leader for the Seahawks with 10 totes for 86 yds (8.6 yds per carry). Jaxon Smith-Njigba had an average of 16.5 yards per catch by accumulating 132 yards on 8 catches. The Seattle Seahawks ended up rushing 20 times and tallied 122 yards, which earned them an average of 6.1 yds per attempt. At the end of the game, they ran 54 plays which totaled 463 yds. Seattle conceded 29 pass completions on 33 attempts for 370 yards, and a completion percentage of 87.9%. On the ground, the Seahawks conceded 56 yards on 24 tries, which averages out to 2.3 yards per run allowed.

The Seahawks have accrued 1,792 yds for the year. Seattle has recorded 59 1st downs as an offense, and they have been called for 27 infractions for 240 yds. Concerning getting the ball in the endzone, Seattle has produced 9 passing TD's and 6 rushing touchdowns. They have given the ball to the opposition 8 times (3 INTs and 5 fumbles lost). As a unit, they maintain an average of 113.0 rushing yds which ranks them at 19th in football. When talking about scoring points, the NFC members hold an average of 29.2 PPG.
The Seahawks are ranking 12th in football with reference to their defensive prowess, yielding 21.0 points per outing. They are giving up an average of 3.3 yds per run and 83.0 running yds per contest over the course of the season. In terms of pass yards, the Seahawks have conceded 1,199 total yards, which ranks 26th in pro football. They have conceded 239.8 total yards per outing through the air, and are surrendering a completion rate of 70.3%. Overall, they are allowing 322.8 total yards per contest, which ranks them at 16th in football. They have granted 8 touchdowns through the air, and 2 touchdowns via the rush. In total, they have granted 415 yards via the ground game in 5 outings for the year.
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The Jaguars head into this matchup 4-1 on the campaign. When they last stepped on the football field, the Jaguars took home the win by a final score of 31-28 when they faced the Kansas City Chiefs. Trevor Lawrence (1 touchdown) ended the contest with 221 yards on 18-25 passing while his QB rating was 95.6. He threw 1 interception and his average yards per pass attempt was 8.8 yds. Brian Thomas had the best day in terms of receiving for the Jaguars, bringing in 4 balls for 80 yds (20.0 yards per reception). Travis Etienne ran the football 12 times for 49 yards, ending the contest with 4.1 yds per carry for Jacksonville. The Jaguars ended up finishing with 319 yds on 51 plays (6.3 yds per play). Jacksonville ended up running for 4.2 yds per carry, finishing the contest with 109 yds on 26 carries. Jacksonville conceded 22 attempts on the ground for 158 yards (7.2 yards per carry). The Jaguars pass defense conceded a completion rate of 70.7%, surrendering 318 yds on 29 for 41 passing.
The Jacksonville Jaguars hold an average of 342.6 total yards per outing, which ranks 15th in pro football. They have an average of 137.0 rushing yds per outing, and have run for 685 yds. They have allowed 5 interceptions while granting 1 fumble, and have earned 50 1st downs. The Jacksonville offense has relinquished 333 total yards on 42 infractions, ranking this team at 5th in the NFL if you look at helping out the opposition. This year, the Jaguars have a total of 1,028 yards via the pass and are averaging 205.6 yards via the pass per outing, ranking this team at 17th in the NFL. With reference to how much they score, the Jaguars are ranking 10th in football, holding an average of 25.4 points per outing.
They have relinquished 8 touchdowns through the air plus 250.4 pass yards per contest, which ranks them at 27th in football. Jacksonville has conceded a total of 489 rushing yds (97.8 total yards per outing), plus 4 touchdowns to rushers over the course of this year. The D has produced 14 turnovers (4 forced fumbles and 10 interceptions) for this campaign. Altogether, they have relinquished 100 points in total. The Jaguars defense has participated in 311 plays from the line of scrimmage, putting them 22nd in the league. The Jaguars are giving up 20.0 points per contest, ranking this team at 8th in the NFL.
Who will win tonight's Seahawks-Jaguars NFL game against the spread?
Guy's Pick: Take the Jaguars -1.5
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Additional Resources:
Jacksonville Jaguars - Twitter
Seattle Seahawks - Twitter