Tampa Bay Buccaneers vs Detroit Lions Prediction, 10/20/2025 NFL Picks, Best Bets & Odds Week 7
Game: Tampa Bay Buccaneers vs Detroit Lions
Date: Monday, October 20, 2025
Location: Ford Field in Detroit, MI
TV: ABC
Odds-Point Spread: Lions (-4.5)
Total-Over-Under: 53
The Detroit Lions (4-2) will try to defeat the Tampa Bay Buccaneers (5-1) at Ford Field on Monday. Tampa Bay opens this contest as 4.5-point dogs. The over-under is 53.
The Tampa Bay Buccaneers head into this game 5-1 over the course of this season. In their last game, the Buccaneers went up against the San Francisco 49ers and earned the victory with a final of 30-19. Baker Mayfield went 17-23 with 256 yards passing and 2 TDs. He had a quarterback rate of 139 and finished the contest with no picks. Rachaad White led the offense in rushing for the Buccaneers with 17 carries for 65 yards (3.8 yards per attempt). Cade Otton averaged 10.2 yds per reception by totaling 51 yds on 5 catches. The Tampa Bay Buccaneers ended up rushing 26 different times and compiled 104 yds, which earned them an average of 4.0 yds per carry. In the game, they tallied 49 plays which gave them 352 yards. Tampa Bay relinquished 27 pass completions on 39 attempts for 296 yards, and a completion rate of 69.2%. Against the run, the Buccaneers gave up 67 yards on 22 attempts, which is an average of 3.0 yds per rush allowed.

If you analyze scoring, the Tampa Bay Buccaneers hold an average of 27.5 points per outing. As a unit, they maintain an average of 109.3 rushing yds ranking them 20th in football. The Buccaneers have a total of 2,121 yards this season. Tampa Bay has racked up 67 first downs, and they have been flagged for 40 infractions for 337 yds. They have given the ball away 2 different times (1 interception and 1 fumble). When you look at scoring points, Tampa Bay has produced 12 passing touchdowns and 5 touchdowns on the ground.
The Buccaneers are ranking 24th in pro football if you look at team defense, conceding 25.2 points per contest. They are allowing 3.7 yards per rush and 88.2 rushing yards per contest this season. When talking about passing yds, the Buccaneers have allowed 1,388 yds, which has them ranked 22nd in pro football. They have granted 231.3 yds per outing through the air, and are conceding a completion rate of 68.3%. On the whole, they are giving up 319.5 yds per outing, ranking them 14th in football. They have granted 10 touchdowns through the air, and 5 touchdowns to rushers. On the whole, they have yielded 529 running yards through 6 contests over the course of this season.
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The Lions step onto the field with a record of 4-2 so far this year. In their last contest, the Lions went home defeated by a final of 30-17 when they played the Kansas City Chiefs. Jared Goff (2 touchdowns) finished the game with 203 yards on 23-29 passing while his quarterback rate was 118.8. He didn't throw any picks and his Y-A was 7.0 yds. Jahmyr Gibbs carried the rock 17 times for 65 yards, finishing the contest with 3.8 yards per carry for Detroit. Amon-Ra St. Brown was the best receiver for the Lions, catching 9 balls for 45 yards (5.0 yards per catch). Detroit ran the football for 4.3 yds per carry, finishing with 98 yards on 23 attempts. The Lions finished the game with 297 yards and they ran 52 plays (5.7 yards per play). The Lions pass defense conceded a completion percentage of 73.3%, relinquishing 243 yds on 22 out of 30 passing. Detroit allowed 29 run attempts for 112 yds (3.9 yards per rush).
If you analyze their ability to score points, the Lions are ranking 2nd in football, scoring 31.8 points per outing. For the year, the Lions have a total of 1,350 passing yds and are sitting at 225.0 passing yds per game, which has them ranked 14th in pro football. They maintain an average of 128.7 rushing yards per contest, and have run for 772 yards. The Detroit Lions hold an average of 353.7 yds per outing, which is good for 11th in football. The Detroit offense has yielded 265 yards by way of 36 violations, which has them sitting 25th in the league when it comes to hurting your team. They have tossed 2 INTs while surrendering 1 fumble, and have earned 75 1st downs offensively.
The Lions are allowing 23.7 PPG, which has them ranked 18th in professional football. They have relinquished 13 touchdowns through the air and 212.7 pass yds per outing, ranking them 14th in pro football. Detroit has yielded a total of 573 rush yds (95.5 yards per contest), as well as 5 touchdowns to rushers so far this season. The Lions defense has participated in 350 plays from the line of scrimmage, which has them ranked 12th in pro football. Their defense has compiled 9 turnovers so far this season. All in all, they have relinquished 142 points.
Who will win tonight's Buccaneers-Lions NFL game against the spread?
Guy's Pick: Take the Lions -4.5
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Additional Resources:
Detroit Lions - Twitter
Tampa Bay Buccaneers - Twitter