Arizona Cardinals vs New York Giants Prediction, 10/4/2026 NFL Picks, Best Bets & Odds Week 4

Game: Arizona Cardinals vs New York Giants

Date: Sunday, October 4, 2026

Location: MetLife Stadium in East Rutherford, NJ

TV: CBS

Odds-Point Spread: Giants -1.5

Total-Over-Under: 43.5

MetLife Stadium is where the New York Giants (2-1) will play the Arizona Cardinals (1-2) on Sunday. New York opens this contest as 1.5-point favorites from Vegas oddsmakers. The total is set at 43.5.

The Arizona Cardinals step onto the field holding a record of 1-2 on the season. In their last game, the Cardinals faced the San Francisco 49ers and went home with a loss by a final score of 36-30. Jacoby Brissett finished 38-52 with 280 yards passing and 2 TDs. He had a quarterback rating of 98.2 and finished the game without throwing a pick. Jeremiyah Love was the leader on the ground for the Cardinals with 21 attempts for 90 yards (4.3 yds per carry). Michael Wilson left with an average of 8.1 yards per catch by accumulating 89 yards on 11 receptions. The Arizona Cardinals ended up rushing 27 times and amassed 93 yds, which had them averaging 3.4 yards per tote. On the day, they ran 79 plays which totaled 365 yds. Arizona conceded 15 completions on 27 attempts for 297 yards, and a completion percentage of 55.6%. In the running game, the Cardinals gave up 140 yards on 23 tries, which calculates to 6.1 yds per run allowed.

The Cardinals have racked up 909 yards over the course of this year. Arizona has racked up 37 first downs offensively, and they have been called for 24 penalties for 245 total yards. When you look at putting points on the board, Arizona has amassed 4 passing TD's and 2 touchdowns via the ground. They have given the ball to the opposition 1 time. As a unit, they are averaging 93.0 rushing yds ranking this team at 25th in professional football. Concerning getting the ball into the endzone, the NFC West members are averaging 21.0 points per game.

With reference to passing yards, the Cardinals have relinquished 703 total yards, which ranks 23rd in pro football. They have granted 234.3 yards per contest via the pass, and are giving up a completion rate of 63.8%. Overall, they have allowed 383 yards via the ground game in 3 contests over the course of this year. They have granted 8 touchdowns via the pass, and 3 touchdowns to runners. Altogether, they are relinquishing 362.0 total yards per contest, ranking this team at 26th in professional football. They are allowing 4.6 yds per rushing attempt and 127.7 rushing yards per contest this season. The Cardinals currently sit 24th in football concerning team defense, surrendering 27.0 points per outing.

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The Giants come into this matchup holding a record of 2-1 this season. In their last game, the Giants got the win with a final of 12-7 against the Tennessee Titans. Cam Skattebo carried the football 20 times for 60 yards, finishing the contest with 3.0 yards per attempt for New York. Cam Skattebo was the top contributor in the passing game for the Giants, snagging 3 footballs for 40 yds (13.3 yards per catch). Jameis Winston ended the game with 118 yds on 14-22 passing while his QB rating was 77.5. He didn't toss any interceptions and his average yds per pass attempt was 5.4 yds. New York surrendered 21 rushing attempts for 81 yds (3.9 yds per carry). The Giants pass defense conceded a completion percentage of 63.9%, surrendering 181 yards on 23 for 36 passing. The Giants finished the game with 238 yards and they ran 55 plays (4.3 yards per play). New York rushed for 4.2 yards per carry, finishing with a total of 138 yds on 33 attempts.

With reference to putting points on the board, the Giants are ranking 28th in professional football, maintaining an average of 15.3 points per contest. On the season, the Giants have a total of 459 passing yds and are averaging 153.0 passing yds per contest, which ranks them 31st in football. They hold an average of 118.3 rushing yds per game, and have carried the football for 355 yards. The New York Giants hold an average of 271.3 total yards per contest, which ranks them 29th in football. The New York offense has relinquished 222 total yards by way of 23 penalties, ranking this team at 12th in professional football when you look at helping out the other team. They have recorded 1 interception while yielding 1 fumble, and have been able to earn 28 1st downs.

The Giants are relinquishing 18.3 points per contest, ranking this team at 9th in professional football. They have surrendered 7 touchdowns through the air along with 224.7 pass yds per contest, ranking this team at 19th in professional football. New York has surrendered a total of 313 rushing yds (104.3 yards per outing), and 1 touchdown by way of the ground game over the course of this year. The Giants defense has been on the field for 169 plays from scrimmage, which has them sitting 7th in football. Their defense has accrued 5 takeaways (2 forced fumbles and 3 picks) so far this year. On the whole, they have granted 55 points.

Who will win tonight's Cardinals-Giants NFL game against the spread?

Josh's Pick: Take the Giants -1.5

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