Carolina Panthers vs New Orleans Saints Prediction, 11/15/2026 NFL Picks, Best Bets & Odds Week 10

Game: Carolina Panthers vs New Orleans Saints

Date: Sunday, November 15, 2026

Location: Caesars Superdome in New Orleans, LA

TV: FOX

Odds-Point Spread: Saints -1.5

Total-Over-Under: 47.5

The New Orleans Saints (3-5) welcome the Carolina Panthers (3-5) at Caesars Superdome on Sunday. Carolina opens this contest as 1.5-point underdogs from Vegas oddsmakers. The betting total comes in at 47.5.

The Carolina Panthers come into this game holding a record of 3-5 for this campaign. In their last game, the Panthers went up against the Denver Broncos and took a loss by a final of 26-21. Chuba Hubbard was the leader on the ground for the Panthers with 16 carries for 79 yds (4.9 yards per attempt). Darren Waller left with an average of 11.3 yds per catch by accumulating 90 yards on 8 catches. Bryce Young went 28-39 with 276 yds passing and 3 TDs. He had a QB rate of 106.4 and finished the game with 1 interception. Against the run, the Panthers gave up 82 yds on 27 attempts, which averages out to 3.0 yards per rush surrendered. Carolina relinquished 25 completions on 37 attempts for 230 yards, and a completion rate of 67.6%. When all was said and done, they ran 59 plays which gave them a total of 353 yards. The Carolina Panthers ended up rushing 20 different times and amassed 96 yards, which is an average of 4.8 yds per attempt.

The Panthers have amassed 2,899 yards so far this year. Carolina has a total of 111 1st downs as an offense, and they have committed 70 penalties for 635 total yards. Regarding notching touchdowns, Carolina has tallied 16 touchdowns via the pass and 7 touchdowns via the ground. They have surrendered the football 12 times (6 picks and 6 fumbles). As a unit, they're maintaining an average of 101.3 running yds which ranks 23rd in football. When you look at scoring, the NFC members average 24.9 points per game.

When you look at passing yards, the Panthers have conceded 1,692 yards, which ranks 6th in football. They have given up 211.5 yards per contest through the air, and are allowing a completion% of 63.3%. On the whole, they have conceded 1,067 yards on the ground through 8 games over the course of the season. They have surrendered 12 touchdowns by way of the pass, along with 13 touchdowns to rushers. In total, they are allowing 344.9 yards per game, which has them ranked 22nd in football. The opposition is running for an average of 4.6 yards per rush and 133.4 running yards per game so far this year. The Panthers currently sit 29th in professional football when talking about their defensive abilities, granting 27.4 PPG.

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The Saints come into this matchup holding a record of 3-5 so far this year. The last time they stepped on the football field, the Saints went home victorious with a score of 23-22 against the Cleveland Browns. Audric Estime carried the football 15 times for 72 yds, ending the game with 4.8 yards per attempt for New Orleans. Chris Olave was the top contributor in the passing game for the Saints, hauling in 7 throws for 98 yards (14.0 yds per reception). Tyler Shough (1 TD) finished the game with 265 yards on 21-35 passing while his QB rating was 93.2. He didn't toss any interceptions and his average yards per pass attempt was 7.6 yards. New Orleans gave up 34 running attempts for 95 yards (2.8 yds per rush). The Saints pass defense conceded a completion percentage of 61.3%, surrendering 260 yds on 19 out of 31 passing. The Saints finished the game with a total of 396 yards while running 67 plays (5.9 yards per play). New Orleans ran the ball for 5.0 yards per attempt, totaling 160 yards on 32 attempts.

The New Orleans Saints hold an average of 325.8 yards per contest, putting them 19th in professional football. They maintain an average of 95.3 running yards per game, and have carried the football for 762 yards. They have recorded 6 interceptions while relinquishing 9 fumbles lost, and have tallied 99 1st downs as a team. The New Orleans offense has relinquished 330 total yards by way of 49 penalties, which is good for 30th in professional football if you look at helping out the opposition. In this campaign, the Saints have a total of 1,844 yards via the pass and hold an average of 230.5 yards via the pass per outing, which is good for 14th in the league. If you examine putting points on the board, the Saints sit 15th in the league, with an average of 23.1 points per game.

They have conceded 13 touchdowns through the air in addition to 236.6 passing yards per contest, which ranks 28th in football. New Orleans has yielded a total of 1,071 running yards (133.9 yards per game), plus 11 touchdowns via the ground game on the season. Their defense has tallied 9 takeaways (5 forced fumbles and 4 interceptions) over the course of the season. Altogether, they have surrendered 216 pts. The Saints defense has been on the field for 521 plays from the line of scrimmage, which is good for 13th in the league. The Saints are conceding 27.0 PPG, putting them 27th in professional football.

Who will win tonight's Panthers-Saints NFL game against the spread?

Guy's Pick: Take the Saints -1.5

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