Cleveland Browns vs Tampa Bay Buccaneers Prediction, 9/20/2026 NFL Picks, Best Bets & Odds Week 2

Game: Cleveland Browns vs Tampa Bay Buccaneers

Date: Sunday, September 20, 2026

Location: Raymond James Stadium in Tampa, FL

TV: CBS

Odds-Point Spread: Browns +8.5

Total-Over-Under: 40.5

Raymond James Stadium is where the Tampa Bay Buccaneers (0-1) will play the Cleveland Browns (0-1) on Sunday. Tampa Bay opens as 8.5-point favorites from oddsmakers. The over-under is 40.5.

The Cleveland Browns head into this game 0-1 for this campaign. In their last contest, the Browns faced the Jacksonville Jaguars and walked away from this one with a loss by a score of 34-10. Deshaun Watson connected on 16-22 with 205 yards through the air and 1 TD. He had a quarterback rating of 97.7 and ended the contest with 1 pick. Quinshon Judkins led the offense in rushing for the Browns with 12 totes for 33 yds (2.8 yards per attempt). KC Concepcion had an average of 10.8 yards per reception by earning 43 yards on 4 catches. The Cleveland Browns ended up running the ball 22 times and totaled 87 yds, earning them an average of 4.0 yds per attempt. When all was said and done, they ran 44 plays which totaled 272 yards. Cleveland allowed 18 pass completions on 23 tries for 234 yards, and a completion percentage of 78.3%. Against the rush, the Browns gave up 126 yds on 32 attempts, which calculates to 3.9 yards per run allowed.

The Browns have accumulated 272 yards over the course of this year. Cleveland has recorded 9 first downs as a team, and they have been called for 11 infractions for 75 yards. When analyzing getting the ball in the endzone, Cleveland has compiled 1 passing touchdown. They have given the ball to the opposition 2 times (1 interception and 1 fumble). As a unit, they average 87.0 rushing yards ranking this team at 24th in the NFL. When talking about putting the ball in the endzone, the Cleveland Browns hold an average of 10.0 points per contest.

If you analyze yards via the pass, the Browns have surrendered 234 total yards, ranking this team at 23rd in the NFL. They have surrendered 234.0 total yards per outing via the pass, and are allowing a completion percentage of 78.3%. Altogether, they have relinquished 126 yards via the running game in 1 game over the course of the season. They have granted 4 touchdowns through the air. Altogether, they are relinquishing 360.0 total yards per contest, which is good for 19th in the league. They are giving up an average of 3.9 yds per run and 126.0 running yards per contest for the season. The Browns sit 27th in professional football if you examine their opponents scoring, surrendering 34.0 points per game.

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The Buccaneers head into this matchup 0-1 for the season. The last time they stepped on the gridiron, the Buccaneers went home defeated by a final of 33-27 when they faced the Cincinnati Bengals. Baker Mayfield finished the game with 216 yds on 23-28 through the air while his QB rating was 98.8. He kept the ball away from the defense with no interceptions and his avg yards per attempt was 7.7 yards. Bucky Irving carried the football 8 times for 45 yards, finishing the contest with 5.6 yards per attempt for Tampa Bay. Bucky Irving was a featured target for the Buccaneers, snagging 7 balls for 48 yards (6.9 yards per reception). Tampa Bay rushed for 4.5 yds per carry, finishing the game with 89 yds on 20 carries. The Buccaneers finished the game with a total of 282 yards while running 48 plays (5.9 yards per play). The Buccaneers pass defense conceded a completion rate of 71.4%, surrendering 245 yards on 25 for 35 through the air. Tampa Bay gave up 27 rushing attempts for 106 yards (3.9 yds per carry).

The Tampa Bay Buccaneers have an average of 282.0 yards per game, which is 21st in pro football. They hold an average of 89.0 rushing yds per contest. They have granted 4 lost fumbles, and have been able to earn 12 1st downs as a unit. The Tampa Bay offense has yielded 39 yards by way of 8 penalty flags, putting them 12th in pro football when it comes to helping out the other team. For the season, the Buccaneers have thrown for 193 passing yds. If you analyze the points being put on the board, the Buccaneers currently sit 13th in the NFL, maintaining an average of 27.0 PPG.

The Buccaneers are giving up 33.0 points per contest, which is 26th in pro football. They have given up 1 touchdown through the air along with 245.0 pass yards per contest, which ranks them at 24th in the league. Tampa Bay has yielded a total of 106 running yds. The Buccaneers defense has participated in 63 plays from the line of scrimmage, ranking them 18th in pro football. The defense has notched 1 turnover so far this season. Overall, they have conceded 33 total points.

Who will win tonight's Browns-Buccaneers NFL game against the spread?

Tony's Pick: Take the Browns +8.5

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