Detroit Lions vs Cincinnati Bengals Prediction, 10/5/2025 NFL Picks, Best Bets & Odds Week 5

Game: Detroit Lions vs Cincinnati Bengals

Date: Sunday, October 5, 2025

Location: Paycor Stadium in Cincinnati, OH

TV: FOX

Odds-Point Spread: Bengals (+10)

Total-Over-Under: 49

The Detroit Lions (3-1) are on their way to Paycor Stadium on Sunday where they will compete against the Cincinnati Bengals (2-2). Cincinnati opens this contest as 10-point dogs from Vegas oddsmakers. The total is set at 49.

The Detroit Lions come into this game holding a record of 3-1 for this campaign. The last time they stepped on the gridiron, the Lions played against the Cleveland Browns and notched a win by a score of 34-10. Jared Goff connected on 16-27 with 168 yards through the air and 2 touchdowns. He had a QB rate of 86.7 and walked away from the game with 1 interception. Amon-Ra St. Brown had an average of 10.0 yards per catch by recording 70 yds on 7 catches. Jahmyr Gibbs led the offense in rushing for the Lions with 15 carries for 91 yards (6.1 yds per attempt). Once the final whistle blew, they had 56 plays which gave them a total of 277 yds. The Detroit Lions ended up rushing 29 times and totaled 109 yds, which came out to an average of 3.8 yds per attempt. When it came to stopping the run, the Lions gave up 79 yards on 27 tries, which calculates to 2.9 yards per run allowed. Detroit relinquished 16 completions on 35 attempts for a total of 170 yds, and a completion percentage of 45.7%.

The Lions have attained 1,460 total yards this year. Detroit has produced 47 1st downs, and they have been hurt by 24 infractions for 171 total yards. If you're looking at scoring points, Detroit has amassed 9 touchdowns through the air and 7 rushing touchdowns. They have turned the football over 2 times. Offensively, they are sitting at 139.0 rushing yds which has them ranked 6th in the NFL. If you examine getting the ball in the endzone, the Detroit Lions average 34.3 points per outing.

The Lions are sitting 15th in professional football when examining opponents scoring, conceding 22.0 points per game. They are allowing 3.8 yds per rush and 94.0 rushing yards per contest for the season. When analyzing pass yards, the Lions have given up 796 yds, which has them ranked 13th in the NFL. They have surrendered 199.0 total yards per game via the pass, and are surrendering a completion percentage of 62.7%. Overall, they are allowing 293.0 yards per contest, putting them 12th in football. They have allowed 7 touchdowns by way of the pass, as well as 4 touchdowns via the rush. Overall, they have granted 376 yards on the ground through 4 games for the season.

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The Bengals head into this matchup 2-2 on the season. The last time they took the field, the Bengals took a loss by a score of 28-3 against the Denver Broncos. Jake Browning ended the game with 125 yds on 14-25 through the air while his QB rate was 69.6. He didn't toss any interceptions and his Y-A was 5.0 yards. Chase Brown ran the football 10 times for 40 yards, ending the contest with 4.0 yards per attempt for Cincinnati. Ja'Marr Chase was a featured target for the Bengals, grabbing 5 passes for 23 yds (4.6 yds per reception). Cincinnati ran the football for 3.5 yds per attempt, finishing the game with 53 yds on 15 carries. The Bengals finished the contest with a total of 159 yards while running 40 plays (4.0 yards per play). The Bengals pass defense gave up a completion percentage of 69.0%, relinquishing 326 yards on 29 for 42 passing. Cincinnati surrendered 38 attempts on the ground for 186 yds (4.9 yards per rush).

If you're looking at the points being put on the board, the Bengals are sitting 30th in football, holding an average of 15.3 points per outing. On the season, the Bengals have thrown for a total of 621 yards via the pass and hold an average of 155.3 yards via the pass per contest, putting them 30th in football. They have an average of 50.0 rushing yards per outing, and have carried the football for 200 yards. The Cincinnati Bengals average 205.3 yds per contest, which has them ranked 32nd in the NFL. The Cincinnati offense has granted 172 total yards on 25 violations, which is 24th in football if you examine hurting your team. They have a total of 5 picks while yielding 3 fumbles lost, and have been able to record 33 first downs as a team.

They have conceded 8 touchdowns by way of the pass plus 262.0 passing yds per outing, which has them ranked 30th in pro football. Cincinnati has surrendered a total of 543 rushing yds (135.8 total yards per game), in addition to 5 touchdowns via the rush for the year. The defense has a total of 5 takeaways for the year. On the whole, they have conceded 119 points. The Bengals defense has been on the field for 279 plays, which is good for 31st in professional football. The Bengals are yielding 29.8 points per outing, which is good for 27th in professional football.

Who will win tonight's Lions-Bengals NFL game against the spread?

Guy's Pick: Take the Lions -10

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