Las Vegas Raiders vs Washington Commanders Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
Game: Las Vegas Raiders vs Washington Commanders
Date: Sunday, September 21, 2025
Location: Northwest Stadium in Landover, MD
TV: FOX
Odds-Point Spread: Commanders (-3.5)
Total-Over-Under: 44.5
The Washington Commanders (1-1) will play the Las Vegas Raiders (1-1) at Northwest Stadium on Sunday. Las Vegas is 3.5-point dogs from Vegas oddsmakers. The betting total comes in at 44.5.
The Las Vegas Raiders step on the gridiron 1-1 this year. In their last contest, the Raiders took on the Los Angeles Chargers and walked away from this one with a loss by a score of 20-9. Geno Smith finished 24-43 with 180 yards through the air. He had a QB rating of 37 and ended the contest with 3 picks. Ashton Jeanty was the best rusher for the Raiders with 11 attempts for 43 yards (3.9 yards per attempt). Jakobi Meyers had an average of 11.3 yards per catch by tallying 68 yds on 6 receptions. The Las Vegas Raiders ended up running the ball 19 times and accumulated 68 yards, which came out to an average of 3.6 yds per carry. On the day, they tallied 62 plays which converted into 218 yds. Las Vegas relinquished 19 pass completions on 27 tries for a total of 236 yds, and a completion rate of 70.4%. In the running game, the Raiders conceded 81 yards on 26 attempts, which averages out to 3.1 yards per rush surrendered.

The Raiders have recorded 607 yards over the course of this year. Las Vegas has produced 25 1st downs, and they have been called for 14 penalties for 124 yards. If you analyze putting the ball in the endzone, Las Vegas has racked up 1 passing touchdown and 1 rushing touchdown. They have surrendered the ball 4 different times. As a unit, they're holding an average of 62.0 running yds which has them ranked 31st in the NFL. When talking about getting in the endzone, the Las Vegas Raiders average 14.5 PPG.
The Raiders currently sit 5th in the NFL if you analyze opponents scoring, relinquishing 16.5 points per contest. They are giving up 3.2 yds per tote and 70.5 rushing yds per contest over the course of this year. If you analyze yards via the pass, the Raiders have surrendered 512 yards, ranking them 27th in football. They have allowed 256.0 yards per contest by way of the pass, and are allowing a completion% of 67.1%. On the whole, they are relinquishing 326.5 yards per contest, which is 19th in professional football. They have surrendered 3 touchdowns by way of the pass. Overall, they have allowed 141 yards via the ground game in 2 contests for the year.
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The Commanders step onto the field with a record of 1-1 on the season. In their last game, the Commanders took a loss by a final score of 27-18 against the Green Bay Packers. Jayden Daniels (2 TDs) walked away from the contest with 200 yards on 24-42 passing while his quarterback rate was 85.4. He didn't toss any picks and his Y-A was 4.8 yds. Zach Ertz was one of the featured targets for the Commanders, hauling in 6 balls for 64 yds (10.7 yds per reception). Jacory Croskey-Merritt ran the football 4 times for 17 yds, ending the game with 4.3 yards per attempt for Washington. The Commanders finished with a total of 230 yards and they ran 61 plays (3.8 yards per play). Washington ran for 2.7 yards per carry, totaling 51 yards on 19 carries. Washington gave up 30 running attempts for 135 yards (4.5 yards per carry). The Commanders pass defense allowed a completion percentage of 61.3%, relinquishing 269 yards on 19 out of 31 passing.
When talking about putting points on the board, the Commanders are ranking 23rd in professional football, holding an average of 19.5 PPG. This season, the Commanders have a total of 391 passing yds and average 195.5 passing yds per outing, which has them sitting 24th in the league. They hold an average of 135.5 running yds per game, and have run for 271 yds. The Washington Commanders have an average of 331.0 total yards per outing, which has them ranked 14th in the NFL. The Washington offense has granted 119 yds by way of 17 penalties, which is good for 8th in professional football when analyzing helping out the other team. They have obtained 21 first downs as a unit.
They have yielded 2 touchdowns via the pass in addition to 213.0 pass yards per contest, which is 18th in professional football. Washington has relinquished a total of 209 rushing yds (104.5 yards per game), in addition to 1 touchdown via the ground game so far this season. The D has recorded 0 turnovers. In total, they have surrendered 33 pts. The Commanders defense has taken the field for 125 plays from scrimmage, which has them sitting 17th in the league. The Commanders are conceding 16.5 PPG, ranking them 6th in football.
Who will win tonight's Raiders-Commanders NFL game against the spread?
Guy's Pick: Take the Commanders -3.5
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Additional Resources:
Washington Commanders - Twitter
Las Vegas Raiders - Twitter