New York Giants vs Washington Commanders Prediction, 9/7/2025 NFL Picks, Best Bets & Odds Week 1
Game: New York Giants vs Washington Commanders
Date: Sunday, September 7, 2025
Location: Northwest Stadium in Landover, MD
TV: FOX
Odds-Point Spread: Commanders (-6)
Total-Over-Under: 45.5
Northwest Stadium is the place where the Washington Commanders (12-5 last year) will try to defeat the New York Giants (3-14 last season) on Sunday. New York opens this matchup as 6-point underdogs from Vegas oddsmakers. The over-under is set at 45.5.
The New York Giants wrapped up their year with a 3-14 record. The last time they stepped on the football field, the Giants faced the Philadelphia Eagles and went home with a loss by a final score of 20-13. Drew Lock went 22-29 with 138 yards passing and 1 TD. He had a quarterback rating of 82.3 and walked away from the contest with 1 interception. Malik Nabers had an average of 12.8 yards per reception by accumulating 64 yds on 5 catches. Tyrone Tracy Jr. was the rushing leader for the Giants with 14 totes for 59 yards (4.2 yards per attempt). At the end of the game, they tallied 54 plays which gave them 238 yds. The New York Giants ended up rushing 25 different times and amassed 100 yds, which earned them an average of 4.0 yards per carry. When it came to stopping the run, the Giants gave up 51 yds on 25 attempts, which is an average of 2.0 yds per run allowed. New York gave up 27 completions on 41 attempts for a total of 252 yds, and a completion rate of 65.9%.

If you're looking at notching touchdowns, the Giants held an average of 16.1 points per contest. As a unit, they maintained an averaged of 104.9 running yards, which ranked 23rd in professional football. The Giants earned 5,011 yds in the previous season. New York produced 170 1st downs as a team, and they were flagged for 112 penalties for 928 yards. They surrendered the football 23 times (13 picks and 10 fumbles). New York accrued 15 passing TD's and 13 touchdowns on the ground.
The Giants ranked 21st in the NFL if you examine the other team scoring points, relinquishing 24.4 points per game. They gave up an average of 4.6 yds per tote and 136.2 running yards per game for the previous season. On the whole, they surrendered 2,316 yards via the ground game in 17 outings for the previous season. If you examine yards through the air, the Giants relinquished 3,580 yds ranking them 8th in football. They surrendered 210.6 yards per game by way of the pass, and conceded a completion% 69.4%. In total, they conceded 346.8 per contest, ranking them 24th in football. They relinquished 23 passing touchdowns, along with 18 to runners.
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The Commanders concluded the year having accumulated a 12-5 mark. When they last stepped on the football field, the Commanders walked away with a loss by a score of 55-23 when they faced the Philadelphia Eagles. Jayden Daniels (1 TD) finished the contest with 255 yards on 29-48 passing while his quarterback rating was 72.8. He threw 1 pick and his average yards per pass attempt was 5.3 yds. Jayden Daniels carried the football 6 times for 48 yds, finishing the game with 8.0 yards per attempt for Washington. Zach Ertz was featured in the passing game for the Commanders, snagging 11 passes for 104 yds (9.5 yards per reception). Washington ran the ball for 4.0 yds per carry, finishing with 99 yards on 25 carries. The Commanders finished the contest with a total of 350 yds and they ran 74 plays (4.7 yds per play). The Commanders passing defense allowed a completion rate of 71.4%, surrendering 230 yds on 20 for 28 through the air. Washington conceded 36 rush attempts for 229 yards (6.4 yards per carry).
Regarding the points being put on the board, the Commanders ranked 5th in the NFL, with 28.5 points per game. Last season, the Commanders had a previous total of 3,665 passing yards and averaged 215.6 passing yards per contest, which was 17th in professional football. They averaged 154.1 rush yards per outing, and toted the ball for 2,619 total yards. The Washington Commanders held an average of 369.6 yds per game, which had them ranked 7th in the NFL. The Washington offense conceded 960 yds by way of 111 infractions, ranking them 13th in football when analyzing helping out the other team.
They conceded 25 touchdowns via the pass and 189.5 passing yards per contest, which had them sitting 3rd in pro football. Washington surrendered a total of 2,337 rushing yds (137.5 yds per game), along with 18 touchdowns via the rush for the previous season. The D recorded 17 takeaways (10 fumbles forced and 7 picks) for the previous season. The Commanders defense participated in 1,029 plays, which ranked them 7th in professional football. The Commanders granted 23.0 points per game, which had them sitting 18th in the NFL.
Who will win tonight's Giants-Commanders NFL game against the spread?
Josh's Pick: Take the Giants +6
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Additional Resources:
Washington Commanders - Twitter
New York Giants - Twitter