Tampa Bay Buccaneers vs Houston Texans Prediction, 9/15/2025 NFL Picks, Best Bets & Odds Week 2
Game: Tampa Bay Buccaneers vs Houston Texans
Date: Monday, September 15, 2025
Location: NRG Stadium in Houston, TX
TV: ESPN
Odds-Point Spread: Texans (-2.5)
Total-Over-Under: 42.5
The Tampa Bay Buccaneers (1-0) are on their way to NRG Stadium on Monday where they will compete against the Houston Texans (0-1). Houston opens this game as 2.5-point favorites from Vegas oddsmakers. The betting total is set at 42.5.
The Tampa Bay Buccaneers head into this matchup 1-0 for this campaign. The last time they stepped on the football field, the Buccaneers stepped onto the field against the Atlanta Falcons and earned the victory with a final of 23-20. Baker Mayfield connected on 17-32 with 167 yds through the air and 3 TDs. He had a QB rating of 99.3 and walked away from the contest with no interceptions. Mike Evans left with an average of 10.2 yds per reception by notching 51 yds on 5 catches. Bucky Irving was the rushing leader for the Buccaneers with 14 carries for 37 yards (2.6 yards per carry). In the game, they tallied 55 plays which gave them 260 yds. The Tampa Bay Buccaneers ran the ball a total of 23 times and compiled 101 yards, which is an average of 4.4 yds per carry. When it came to stopping the run, the Buccaneers conceded 69 yards on 28 attempts, which calculates to 2.5 yds per run allowed. Tampa Bay gave up 27 completions on 42 attempts for 289 yards, and a completion rate of 64.3%.

The Buccaneers have recorded 260 yards over the course of the season. Tampa Bay has notched 10 first downs as a unit, and they have committed 5 penalties for 60 yards. If you look at putting the ball in the endzone, Tampa Bay has tallied 3 passing touchdowns and 0 touchdowns on the ground. They haven't turned the ball over yet. As a team, they're holding an average of 101.0 rush yds which has them ranking 17th in the league. If you're looking at scoring touchdowns, the group who plays in Tampa Bay hold an average of 23.0 points per game.
If you're looking at pass yds, the Buccaneers have relinquished 289 yards, putting them 29th in the NFL. They are surrendering a completion percentage of 64.3%. They have relinquished 1 touchdown via the pass, along with 1 touchdown via the ground game. On the whole, they are yielding 358.0 total yards per game, ranking them 23rd in pro football. They are allowing an average of 2.5 yds per running attempt and 69.0 rushing yds per outing over the course of this year. The Buccaneers currently sit 14th in the league when it comes to the opposition scoring, relinquishing 20.0 points per game.
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The Texans step on the gridiron with a record of 0-1 on the year. In their last game, the Texans took a loss by a score of 14-9 against the Los Angeles Rams. C.J. Stroud ended the game with 188 yards on 19-27 through the air while his QB rating was 74.3. He had 1 interception and his avg yards per attempt was 7.0 yards. Cade Stover was one of the featured targets for the Texans, bringing in 4 footballs for 22 yds (5.5 yards per reception). Nick Chubb carried the ball 13 times for 60 yds, walking away from the contest with 4.6 yards per carry for Houston. The Texans finished the game with 265 yards and they ran 54 plays (4.9 yards per play). Houston ran for 4.2 yards per carry, finishing with a total of 114 yds on 27 carries. Houston allowed 25 rush attempts for 72 yards (2.9 yds per rush). The Texans secondary gave up a completion percentage of 72.4%, surrendering 224 yards on 21 for 29 passing.
The Houston Texans maintain an average of 265.0 yards per game, putting them 23rd in the NFL. They have run for 114 yds. The Houston offense has relinquished 80 yards on 11 penalty flags, which has them ranking 6th in the league when it comes to helping out the other team. For the season, the Texans sit at 151 yards through the air which has them sitting 24th in the league. When talking about how much they score, the Texans rank 30th in professional football, with 9.0 points per game.
The Texans are relinquishing 14.0 PPG, which ranks 10th in professional football. They have relinquished 1 touchdown via the pass plus 224.0 pass yds per game, putting them 23rd in the NFL. Houston has granted a total of 72 running yards. The Texans defense has taken part in 57 plays from scrimmage, which is 12th in professional football. The D has tallied 1 turnover.
Who will win tonight's Buccaneers-Texans NFL game against the spread?
Josh's Pick: Take the Buccaneers +2.5
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Additional Resources:
Houston Texans - Twitter
Tampa Bay Buccaneers - Twitter