Tennessee Titans vs Denver Broncos Prediction, 9/7/2025 NFL Picks, Best Bets & Odds Week 1

Game: Tennessee Titans vs Denver Broncos

Date: Sunday, September 7, 2025

Location: Empower Field at Mile High in Denver, CO

TV: FOX

Odds-Point Spread: Broncos (-8)

Total-Over-Under: 42.5

Empower Field at Mile High is the location where the Denver Broncos (10-7 last year) will meet the Tennessee Titans (3-14 last season) on Sunday. Tennessee opens this contest as 8-point dogs from Vegas oddsmakers. The betting total is set at 42.5.

The Tennessee Titans wrapped up their year having a 3-14 record. The last time they stepped on the gridiron, the Titans faced the Houston Texans and took a loss by a score of 23-14. Will Levis connected on 9-17 with 175 yds through the air and 1 touchdown. He had a QB rating of 108.7 and finished the game without throwing a pick. Calvin Ridley averaged 25.3 yds per catch by accumulating 76 yards on 3 receptions. Tony Pollard was the rushing leader for the Titans with 22 totes for 62 yards (2.8 yards per carry). When the final whistle blew, they ran 58 plays which converted into 314 yds. The Tennessee Titans rushed the ball a total of 32 different times and recorded 85 yards, which earned them an average of 2.7 yards per attempt. When it came to stopping the run, the Titans gave up 207 yds on 29 attempts, which is an average of 7.1 yds per run allowed. Tennessee surrendered 18 pass completions on 28 attempts for 167 yards, and a completion rate of 64.3%.

Concerning getting in the endzone, the Titans averaged 18.3 PPG. As a team, they had an average of 109.1 rushing yds, putting them 20th in football. The Titans amassed 5,172 yards for the prior campaign. Tennessee had a total of 164 first downs as a team, and they were flagged for 132 infractions for 1030 yds. They coughed up the ball 34 times (21 INTs and 13 fumbles lost). Tennessee earned 22 passing touchdowns and 11 ground TD's.

The Titans were 30th in professional football if you're looking at their opponents scoring, granting 27.1 points per outing. They gave up an average of 4.5 yards per run and 133.9 rush yards per game in the previous season. Overall, they allowed 2,277 yards via the running game in 17 games over the course of last season. If you're looking at passing yds, the Titans surrendered 3,014 yds which had them ranked 2nd in the NFL. They conceded 177.3 yds per game via the pass, and gave up a completion percentage 66.4%. Overall, they granted 311.2 per game, which ranked 2nd in professional football. They conceded 27 passing TD's, and 21 by way of the ground game.

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The Broncos culminated the season having produced a 10-7 record. The last time they stepped on the gridiron, the Broncos walked away with a loss by a score of 31-7 against the Buffalo Bills. Bo Nix carried the ball 4 times for 43 yards, finishing the contest with 10.8 yards per attempt for Denver. Courtland Sutton was featured in the passing game for the Broncos, catching 5 footballs for 75 yards (15.0 yds per catch). Bo Nix (1 touchdown) walked away from the contest with 144 yards on 13-22 through the air while his quarterback rating was 93.7. He didn't throw any picks and his average yds per pass attempt was 6.5 yards. Denver conceded 44 running attempts for 210 yds (4.8 yds per carry). The Broncos pass defense allowed a completion rate of 76.9%, surrendering 261 yds on 20 for 26 passing. The Broncos finished the game with 224 yds and they ran 40 plays (5.6 yds per play). Denver rushed the ball for 4.6 yds per carry, finishing with a total of 79 yards on 17 carries.

If you examine how much they score, the Broncos were 10th in pro football, with an average of 25.0 points per contest. For the previous season, the Broncos had a previous total of 3,610 pass yards and averaged 212.4 pass yards per outing, which had them ranking 20th in football. They held an average of 112.2 rushing yds per game, and carried the ball for 1,908 yds. The Denver Broncos were sitting at 324.6 total yards per contest, which ranked them 19th in professional football. The Denver offense granted 941 yards by way of 108 violations, which ranked 20th in professional football if you're looking at helping out the opposition.

They relinquished 22 touchdowns by way of the pass along with 220.7 yards through the air per contest, ranking them 19th in football. Denver conceded a total of 1,639 rushing yds (96.4 yds per contest), along with 10 touchdowns to runners for the previous season. The D collected 25 takeaways (10 fumbles forced and 15 interceptions) last season. The Broncos defense took the field for 1,093 plays from the line of scrimmage, which had them sitting 28th in the NFL. The Broncos relinquished 18.3 points per game, which had them ranking 3rd in football.

Who will win tonight's Titans-Broncos NFL game against the spread?

Guy's Pick: Take the Titans +8

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