Free College Football Picks: Today's Expert Picks Against the Spread, College Football Best Bets, Predictions and Parlays.

Boston College Eagles vs Stanford Cardinal Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Boston College Eagles (1-1) are headed to Stanford Stadium on Saturday, September 13, 2025 where they will play the Stanford Cardinal (0-1). Boston College is 10.5-point favorites. The betting total is set at 45. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Vanderbilt Commodores vs South Carolina Gamecocks Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

Williams-Brice Stadium is where the South Carolina Gamecocks (1-0) will compete against the Vanderbilt Commodores (2-0) on Saturday, September 13, 2025. South Carolina opens this contest as 5.5-point favorites. The total is 47. This matchup report includes Vegas odds and a free college football prediction for tonight.

Kansas State Wildcats vs Arizona Wildcats Prediction, 9/12/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Arizona Wildcats (1-0) will try to beat the Kansas State Wildcats (1-2) at Arizona Stadium on Friday, September 12, 2025. Kansas State opens this contest as 1.0-point dogs from oddsmakers. The total is 54.5. This matchup report includes football betting lines and our pick of the day for this game.

Oklahoma Sooners vs Temple Owls Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Lincoln Financial Field is the location where the Temple Owls (2-0) will play the Oklahoma Sooners (2-0) on Saturday, September 13, 2025. Oklahoma opens as 24.5-point favorites. The total comes in at 51. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

Western Michigan Broncos vs Illinois Fighting Illini Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Illinois Fighting Illini (2-0) will compete against the Western Michigan Broncos (0-2) at Memorial Stadium on Saturday, September 13, 2025. Western Michigan opens this matchup as 28.0-point dogs from oddsmakers. The total is 52. This matchup report includes odds, betting predictions and a free pick against the spread.

Wisconsin Badgers vs Alabama Crimson Tide Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Alabama Crimson Tide (1-1) are hosting the Wisconsin Badgers (2-0) at Bryant-Denny Stadium on Saturday, September 13, 2025. Alabama opens as 20.5-point favorites. The total comes in at 47. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

MTSU Blue Raiders vs Nevada Wolf Pack Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Nevada Wolf Pack (1-1) will take on the MTSU Blue Raiders (0-2) at Mackay Stadium on Saturday, September 13, 2025. Nevada opens this contest as 9.0-point favorites from oddsmakers. The total has been set at 47. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Eastern Michigan Eagles vs Kentucky Wildcats Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Kentucky Wildcats (1-1) will take on the Eastern Michigan Eagles (0-2) at Kroger Field on Saturday, September 13, 2025. Kentucky is 25.0-point favorites from Vegas oddsmakers. The betting total is set at 46.5. This report has odds and your NCAA football predictions for todays game against the spread.

Memphis Tigers vs Troy Trojans Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

Veterans Memorial Stadium is the location where the Troy Trojans (1-1) will attempt to beat the Memphis Tigers (2-0) on Saturday, September 13, 2025. Memphis opens this contest as 5.0-point favorites. The total comes in at 50. This report includes betting odds and our expert football picks for todays game.

Duke Blue Devils vs Tulane Green Wave Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

Yulman Stadium is the location where the Tulane Green Wave (2-0) will attempt to defeat the Duke Blue Devils (1-1) on Saturday, September 13, 2025. Duke opens this game as 3.0-point dogs. The total is 53. This report includes betting odds and our expert football picks for todays game.

Air Force Falcons vs Utah State Aggies Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

Maverik Stadium is the site where the Utah State Aggies (1-1) will play the Air Force Falcons (1-0) on Saturday, September 13, 2025. Air Force opens this game as 4.0-point favorites. The betting total is set at 52. This matchup report includes Vegas odds and a free college football prediction for tonight.

Old Dominion Monarchs vs Virginia Tech Hokies Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Old Dominion Monarchs (1-1) are headed to Lane Stadium on Saturday, September 13, 2025 where they will go up against the Virginia Tech Hokies (0-2). Old Dominion opens this contest as 7.5-point dogs. The over/under is 51. This matchup report includes Vegas odds and a free college football prediction for tonight.

Central Michigan Chippewas vs Michigan Wolverines Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Michigan Wolverines (1-1) are welcoming the Central Michigan Chippewas (1-1) at Michigan Stadium on Saturday, September 13, 2025. Central Michigan is 28.0-point underdogs. The total has been set at 42. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

UMass Minutemen vs Iowa Hawkeyes Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Iowa Hawkeyes (1-1) will play the UMass Minutemen (0-2) at Kinnick Stadium on Saturday, September 13, 2025. UMass is 34.0-point underdogs from Vegas oddsmakers. The betting total is set at 44.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Clemson Tigers vs Georgia Tech Yellow Jackets Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Georgia Tech Yellow Jackets (2-0) will try to defeat the Clemson Tigers (1-1) at Bobby Dodd Stadium on Saturday, September 13, 2025. Georgia Tech opens as 4.0-point underdogs. The total comes in at 52. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Jacksonville State Gamecocks vs Georgia Southern Eagles Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

Allen E. Paulson Stadium is the site where the Georgia Southern Eagles (0-2) will meet the Jacksonville State Gamecocks (1-1) on Saturday, September 13, 2025. Georgia Southern opens this contest as 3.5-point favorites from oddsmakers. The over/under is set at 58. This games report has current odds, betting predictions, and free picks against the spread.

Florida Gators vs LSU Tigers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The Florida Gators (1-1) are hitting the road to Tiger Stadium on Saturday, September 13, 2025 where they will go up against the LSU Tigers (2-0). LSU opens as 9.5-point favorites. The total is set at 50. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Liberty Flames vs Bowling Green Falcons Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Liberty Flames (1-1) are hitting the road to Doyt L. Perry Stadium on Saturday, September 13, 2025 where they will try to defeat the Bowling Green Falcons (1-1). Liberty opens this game as 6.5-point favorites. The total has been set at 51.5. This report includes betting odds and our expert football picks for todays game.

Texas A&M Aggies vs Notre Dame Fighting Irish Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/8/2025

The Texas A&M Aggies (2-0) are traveling to Notre Dame Stadium on Saturday, September 13, 2025 where they will compete against the Notre Dame Fighting Irish (0-1). Notre Dame opens this game as 6.5-point favorites from oddsmakers. The total has been set at 49. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Colorado Buffaloes vs Houston Cougars Prediction, 9/12/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

TDECU Stadium is the site where the Houston Cougars (2-0) will play the Colorado Buffaloes (1-1) on Friday, September 12, 2025. Colorado opens this game as 4.5-point dogs. The over/under is 44.5. This report includes betting predictions and our expert college football picks for todays game.

Utah Utes vs Wyoming Cowboys Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

War Memorial Stadium is the site where the Wyoming Cowboys (2-0) will attempt to defeat the Utah Utes (2-0) on Saturday, September 13, 2025. Utah opens this matchup as 23.5-point favorites. The total has been set at 48. This matchup report includes betting lines and our NCAA football pick of the day for this game.

USC Trojans vs Purdue Boilermakers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/8/2025

The Purdue Boilermakers (2-0) will play the USC Trojans (2-0) at Ross-Ade Stadium on Saturday, September 13, 2025. Purdue opens this contest as 21.0-point dogs. The over/under comes in at 58.5. This games report has current odds, betting predictions, and free picks against the spread.

Florida Atlantic Owls vs FIU Panthers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

The FIU Panthers (1-1) will go up against the Florida Atlantic Owls (1-1) at Pitbull Stadium on Saturday, September 13, 2025. FIU opens this game as 3.0-point favorites from Vegas oddsmakers. The betting total comes in at 57. This matchup report includes betting lines and our NCAA football pick of the day for this game.

Oregon State Beavers vs Texas Tech Red Raiders Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/8/2025

Jones AT&T Stadium is where the Texas Tech Red Raiders (2-0) will try to defeat the Oregon State Beavers (0-2) on Saturday, September 13, 2025. Texas Tech opens this game as 24.5-point favorites. The total is set at 61. This matchup report includes Vegas odds and a free college football prediction for tonight.

UAB Blazers vs Navy Midshipmen Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Navy-Marine Corps Memorial Stadium is where the Navy Midshipmen (1-0) will attempt to defeat the UAB Blazers (1-0) on Saturday, September 6, 2025. Navy opens as 21.0-point favorites. The total is 60. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Iowa Hawkeyes vs Iowa State Cyclones Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

The Iowa Hawkeyes (1-0) are en route to Jack Trice Stadium on Saturday, September 6, 2025 where they will compete against the Iowa State Cyclones (2-0). Iowa opens this game as 3.0-point underdogs. The over/under has been set at 41.5. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Central Michigan Chippewas vs Pittsburgh Panthers Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

The Pittsburgh Panthers (1-0) will compete against the Central Michigan Chippewas (1-0) at Acrisure Stadium on Saturday, September 6, 2025. Pittsburgh opens this game as 22.0-point favorites. The over/under has been set at 52. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Kennesaw State Owls vs Indiana Hoosiers Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Memorial Stadium is the site where the Indiana Hoosiers (1-0) will take on the Kennesaw State Owls (0-1) on Saturday, September 6, 2025. Indiana opens this game as 35.0-point favorites from Vegas oddsmakers. The betting total is set at 52.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Fresno State Bulldogs vs Oregon State Beavers Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Reser Stadium is where the Oregon State Beavers (0-1) will compete against the Fresno State Bulldogs (1-1) on Saturday, September 6, 2025. Fresno State opens this matchup as 3.0-point dogs. The total has been set at 47.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner.

Bowling Green Falcons vs Cincinnati Bearcats Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

Nippert Stadium is where the Cincinnati Bearcats (0-1) will meet the Bowling Green Falcons (1-0) on Saturday, September 6, 2025. Cincinnati is 21.5-point favorites. The betting total comes in at 46.5. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Utah State Aggies vs Texas A&M Aggies Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Kyle Field is where the Texas A&M Aggies (1-0) will try to defeat the Utah State Aggies (1-0) on Saturday, September 6, 2025. Texas A&M opens this matchup as 31.0-point favorites. The total has been set at 54. This report includes betting odds and our expert football picks for todays game.

Texas State Bobcats vs UTSA Roadrunners Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/4/2025

The UTSA Roadrunners (0-1) host the Texas State Bobcats (1-0) at Alamodome on Saturday, September 6, 2025. Texas State opens this contest as 4.5-point underdogs from Vegas oddsmakers. The total comes in at 66. This report has odds and your NCAA football predictions for todays game against the spread.

West Virginia Mountaineers vs Ohio Bobcats Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Peden Stadium is the site where the Ohio Bobcats (0-1) will compete against the West Virginia Mountaineers (1-0) on Saturday, September 6, 2025. Ohio opens as 3.5-point dogs. The over/under is set at 60. This report includes betting odds and our expert football picks for todays game.

FIU Panthers vs Penn State Nittany Lions Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Parlays Pundit - 9/4/2025

Beaver Stadium is where the Penn State Nittany Lions (1-0) will go up against the FIU Panthers (1-0) on Saturday, September 6, 2025. Penn State opens this game as 41.5-point favorites. The betting total comes in at 54.5. We have included an expert college football pick and parlay for todays game against the spread.

NIU Huskies vs Maryland Terrapins Prediction, 9/5/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

The NIU Huskies (1-0) are en route to SECU Stadium on Friday, September 5, 2025 where they will take on the Maryland Terrapins (1-0). Maryland opens this contest as 18.0-point favorites. The over/under is 47.5. This report includes betting predictions and our expert college football picks for todays game.

Illinois Fighting Illini vs Duke Blue Devils Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

The Illinois Fighting Illini (1-0) are en route to Wallace Wade Stadium on Saturday, September 6, 2025 where they will try to defeat the Duke Blue Devils (1-0). Duke opens this game as 3.0-point dogs. The total is 49.5. This matchup report includes Vegas odds and a free college football prediction for tonight.

Arizona State Sun Devils vs Mississippi State Bulldogs Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Davis Wade Stadium is where the Mississippi State Bulldogs (1-0) will take on the Arizona State Sun Devils (1-0) on Saturday, September 6, 2025. Arizona State opens this matchup as 6.5-point favorites. The total comes in at 59. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup.

Baylor Bears vs SMU Mustangs Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/4/2025

The SMU Mustangs (1-0) will take on the Baylor Bears (0-1) at Gerald J. Ford Stadium on Saturday, September 6, 2025. Baylor opens this game as 2.5-point underdogs from Vegas oddsmakers. The over/under comes in at 65. This games report has current odds, betting predictions, and free picks against the spread.

Miami RedHawks vs Rutgers Scarlet Knights Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/4/2025

SHI Stadium is where the Rutgers Scarlet Knights (1-0) will compete against the Miami RedHawks (0-1) on Saturday, September 6, 2025. Rutgers opens as 15.0-point favorites. The over/under is set at 46.5. This games report has current odds, betting predictions, and free picks against the spread.

Connecticut Huskies vs Syracuse Orange Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

The Connecticut Huskies (1-0) are headed to JMA Wireless Dome on Saturday, September 6, 2025 where they will meet the Syracuse Orange (0-1). Connecticut is 6.5-point dogs. The total is 58. This matchup report includes Vegas odds and a free NCAA football pick for tonight.

San Diego State Aztecs vs Washington State Cougars Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Guy Bruhn - 9/4/2025

Martin Stadium is where the Washington State Cougars (1-0) will take on the San Diego State Aztecs (1-0) on Saturday, September 6, 2025. Washington State opens as 1.5-point favorites from oddsmakers. The over/under comes in at 45. This matchup report has your NCAA football pick of the day as well as college football odds for the game.

Liberty Flames vs Jacksonville State Gamecocks Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/4/2025

The Jacksonville State Gamecocks (0-1) are welcoming the Liberty Flames (1-0) at AmFirst Stadium on Saturday, September 6, 2025. Liberty opens this matchup as 6.0-point favorites. The over/under has been set at 50. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread.

San Jose State Spartans vs Texas Longhorns Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Josh Schonwald - 9/4/2025

DKR-Texas Memorial Stadium is where the Texas Longhorns (0-1) will take on the San Jose State Spartans (0-1) on Saturday, September 6, 2025. Texas opens this contest as 37.0-point favorites. The over/under comes in at 51.5. This matchup report includes football betting lines and our pick of the day for this game.

Army Black Knights vs Kansas State Wildcats Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
by Tony Sink - 9/4/2025

Bill Snyder Family Stadium is where the Kansas State Wildcats (1-1) will take on the Army Black Knights (0-1) on Saturday, September 6, 2025. Army opens this game as 17.0-point underdogs from Vegas oddsmakers. The over/under is set at 46.5. This matchup report includes odds, betting predictions and a free pick against the spread.