Thursday Night Football Picks: Dallas Cowboys at Philadelphia Eagles Predictions

by Mike Allen - 9/2/2025

We're now just days away from the 2025 NFL Kickoff Game between the defending Super Bowl Champion Philadelphia Eagles and the visiting NFC East Division rival Dallas Cowboys. The banners will be raised for the champs. How will this affect their emotions going into the game?

Will we see an adrenaline dump? I doubt it because these men are professionals, and I'm sure head coach Nick Sirianni has had them rehearse this as well as coached them on managing their emotions.

From there, we’ve got a home favorite above a touchdown at (-8). How did we get here? Well, it’s a story as old as time or as old as the first old timer, I should say.

The outspoken owner of the Dallas Cowboys, Jerry Jones, like many of our parents, is getting old. He had a generational talent on the edge who could rush the passer at an elite level, all the while beating ballcarriers, running backs, and QBs alike, to the corner.

There aren’t many players who can get fooled on a play action, recover, and still make a highlight tackle. The Cowboys trading him to an NFC contender solely for draft picks tells us all we need to know about his commitment to winning in 2025.

Even if ‘Dem Boys get behind each other and play with passion, it’ll probably only be for a half of football.

Doc’s Sports offers NFL expert picks for every game on our NFL predictions page.

Dallas Cowboys (+8) at Philadelphia Eagles (-8)

Losing Parsons is devastating for the Cowboys' defense, though. The line opened up at (-7) for Philly, and it even dipped to (-6.5) there for a few days. Then the news came in about the trade, and here we are above the key number of 7 in a division game.

Moneyline

Cowboys: +325

Eagles: -425

The Eagles weren't a bad moneyline parlay team if that's what you like, but the betting odds have shifted dramatically, and adding their moneyline to anything you have going won't bring enough value to be worth it.

Point Total: 47.5

As you probably know, 47 is a very key number in NFL point total betting. The sportsbooks want us to take the under. They know that we’re thinking about what we’ve learned in early seasons’ past when we’re in this position, and that is to take the under.

It typically takes offenses longer to click than defensive units. We can’t ignore the elephant in the room, though. Losing Parsons is a dagger for this defense.

Dallas Cowboys at Philadelphia Eagles Betting Analysis

A lot is riding on the shoulders of Dak Prescott this week, more than usual. Yes, he now has one of the best deep threats in the NFL with George Pickens. When you think about it, with the help of CeeDee Lamb, who can run elite short to medium routes, they could be the most effective wide receiver duo in the league.

An 8-point spread simply isn’t safe against firepower like that. Let’s attack this from a different angle. Pickens has betting odds of (-115) to go over 53.5 yards receiving.

In his time playing for the Steelers, he was the WR1, yes, but he didn’t have much help.

Now with a better quarterback and a legit WR1 lining up on the other side, Pickens will get a lot of deep looks from Prescott.

This also aligns with the game's narrative. I thought about taking him to go over his reception total of only 4.5.

The Cowboys will likely be in obvious passing downs. Philly showed us, though, in the Super Bowl, that they will take chances in the secondary. All we need is one long reception from Pickens and a screen or two.

His size is a problem.

Dallas Cowboys at Philadelphia Eagles Betting Pick

Pick: George Pickens Over 53.5 Yards Receiving (-115)

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Start:	September 23, 2025 @ 10:00 PM
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Thursday Night Football Picks: Dallas Cowboys at Philadelphia Eagles Predictions

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