2025 Arizona Cardinals Predictions with Odds to Win the Super Bowl and Season Win Totals

by Spencer Toth - 7/29/2025

Arizona Cardinals predictions Kyler Murray

The Arizona Cardinals will enter their seventh year of the Kyler Murray project, having a single Wild Card playoff defeat to show for it. They have retooled their roster in the offseason and will be looking to compete in a very competitive NFC West. Can the Cardinals find a way to regain their relevance, or will it be another lost season in Arizona?

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Offseason Recap

The Cardinals remained extremely consistent on the offensive side of the ball, with all 11 projected Week 1 starters having been a Cardinal last season. That is very rare in the modern-day NFL, but the Cardinals are still expecting to get better as Marvin Harrison Jr, Trey Benson, and Isiah Adams all enter their second year in the league. Rookie growth will be the primary target on offense, but the story could not be more different on the defensive side of the ball.

Arizona made pass rushing a priority in the offseason, picking up both Josh Sweat and Dalvin Tomlinson. Sweat is the marquee signing of the summer in Arizona, as he will make an instant impact for the Cardinals. The longtime Eagle is bringing plenty of playoff experience with him to Arizona, including a fantastic showing in Super Bowl LIX. Sweat has logged at least 6 sacks in five straight seasons and is also capable of slowing down the run. Tomlinson will not make as much of an instant impact, but he is still an NFL veteran capable of shutting down the run while providing a leadership presence the Cardinals have been missing. Once you factor in the impact first-round draft pick, Walter Nolen (DT) will make, this will suddenly be a daunting pass rush. Compared to most NFL teams, the Cardinals remained relatively quiet this offseason, but they will expect to be marginally better on both sides of the ball.

Season Expectations

The Arizona Cardinals will be expecting to qualify for the postseason, but it is hard to realistically say their expectations are much higher. Kyler Murray is an average NFL quarterback with an average set of skill players around him. His lack of physicality will always limit his ceiling, and he has been unable to make the plays on the move that the coaching staff expected. He is certainly capable of making a playoff run with Arizona. One of the big reasons Murray is set up for success is Marvin Harrison Jr. The 2024 fourth overall pick failed to live up to expectations last season, but he is due for a big jump in Year 2. Harrison Jr. can beat defenders with straight-line speed, but he can also make contested catches when he needs to.

Their run game was 7th in the league with James Conner leading the way last season, and they could get even better if Trey Benson proves to be a suitable one-two punch. Benson had an excellent rookie campaign, and the modern-day NFL offense thrives with a fresh running back tandem to punish teams on the ground. The ceiling for the Cardinals will only be as high as Kyler Murray takes them, as they have an average defense that could be slightly better this season. They will not suddenly become a lockdown team on that side of the ball, and simply need Murray to pull out a few magical moments if they hope to prevail in the NFC West. The Cardinals finished 8-9 despite finishing with a +21 point differential last season, so a few coin-flip games that fall in their direction, and this is suddenly a double-digit win team.

Schedule Breakdown

A team’s schedule can break or break their season. The Cardinals finished 8-9 in third place last season, and have the 7th easiest schedule based on last year’s win percentages. However, the Seahawks, Rams, and 49ers are all expected to improve, which will make winning the division that much harder. Arizona opens up the year with a pair of games against the Saints and Panthers. These are two of their easiest games on the schedule, and getting off to a hot start will be critical if they expect to play postseason football this year. To take it even further, the first 10 games of their schedule also include matchups against the Titans, Colts, and Jaguars. The Cardinals almost certainly need to go 6-4 or even 7-3 as their final five games are against the Bengals, Texans, Falcons, and two against the Rams.

Arizona Cardinals Odds

The Cardinals have a win total of 8.5 games, meaning they are expected to hover right around the .500 mark this season. Their relatively easy schedule certainly plays a role, as Arizona has only 16 wins in their last 3 seasons combined. Regarding the playoffs, the Cardinals are +125 to qualify for the postseason and have -150 odds to miss the playoffs. These are relatively accurate given the current state of the Cardinals and their division, as it will probably take 10 wins to make the playoffs in the NFC this season. Arizona is +425 to win the division, meaning the oddsmakers think their most likely path to playoff football is through the Wild Card, and I would have to agree. Don’t even think about taking a long shot with Arizona to win the NFC (+2500) or Super Bowl (+5000), as there are simply too many contenders to expect Arizona to win three or more playoff games.

2025 Arizona Cardinals Season Predictions and Best Bets

The Arizona Cardinals are expected to be a very average NFL team, but that is only if everything goes right. Kyler Murray has only won nine or more games once in his six-year NFL career, and getting 50/50 odds on him to do so again is not an accurate reflection of where this team is at. The Cardinals made some improvements on the defensive side of the ball, but their offense is still missing a true game-changer. Maybe this is the year Marvin Harrison Jr. breaks out and wins this team a few games, but more often than not, they fall into mediocrity again. I expect the Cardinals to have a respectable season, but to still be out of playoff contention with a couple of weeks left in the season. A 7-10 record sounds about right, making Under 8.5 wins at -110 odds a great pick to make. If you are looking for a future with a higher payout for the Cardinals, consider taking them to finish fourth in the NFC West at +220 odds. The Rams and 49ers are expected to compete for the division crown, but it is hard to be too confident that Arizona will finish ahead of Seattle. The Seahawks have undergone a massive overhaul to their offense, but they have the talent, experience, and coaching needed to edge out Arizona for third place. At +220 odds, you aren’t going to find a better bet around the Cardinals this offseason.

Pick: Arizona Cardinals Under 8.5 Wins -110

Top Pick: Arizona Cardinals to Finish 4th in the NFC West +220

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2025 Arizona Cardinals Predictions with Odds to Win the Super Bowl and Season Win Totals

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